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The map label for this gene is queC

Identifier: 148653563

GI number: 148653563

Start: 2186488

End: 2187258

Strand: Direct

Name: queC

Synonym: PsycPRwf_1766

Alternate gene names: 148653563

Gene position: 2186488-2187258 (Clockwise)

Preceding gene: 148653562

Following gene: 148653564

Centisome position: 73.4

GC content: 49.94

Gene sequence:

>771_bases
ATGACTGATGCCTCAGCAGATGCTTTAACCTCACCCTCTAACAGTGGCGCAAGCCAAGATACTTCTCAGCAAAACGCGGT
GGTACTTCTCTCAGGCGGGCTAGACTCTGTCACTTGCTTATACTGGGCAAAAGCGCGCTATGCCAAAGTCACGGCTGTGA
GTTTTAACTATGGTCAACGTCATAACAGTGAATTGGTCGCAGCCAAAAGCATCGCTGGCCAAGCTGGCGTCAATCATAAA
ATCATCGATATCGATATTGCGCAGTTAGGCGGCTCTTCATTAACTGACCATGATATGACCGTTCCAGATGGCGATGCGGA
CAAATTCCCAACGCATACCGATGACATTGACAACCAAGCCATCCCGAATACCTATGTCCCTGCGCGCAACACCATATTTT
TATCCTACGCGCTAGCTGTCGCAGAGGTTACCGATGCCAACCACATCGTCATTGGCGTAAGCTCAGTCGACTATTCAGGC
TATCCAGATTGTCGCCCTGAATATATCGAAGCCTTTGAAGTGATGGCAAACTTAGCCACCAAAGCGGGAGTGACCGGCCA
CAAACTACACATCCAGACACCACTACAAAAGCTTAGCAAAGCACAGACTATTCAGCTCGGCAACTCATTGGGTGTAGACT
ACTCGCAAACCATTTCGTGTTACAAAGCTGACAGCGAAGGCCGAGCTTGCGGTATCTGTGACAGCTGCACTCTGCGCAAA
AGAGGCTTTAGTGATGCCGGATTGGCCGACCCTACCCGTTATGCCGGCTAA

Upstream 100 bases:

>100_bases
CCCAGTGGCGTCATTTTTGTTAAAATAGACGGTTTTTATTGCCCCATTGTTATTTTAATAACTGCCATTTTTAATTTTTT
AAGCCTTTTAGGACACCCTT

Downstream 100 bases:

>100_bases
TAAAATGGCTTTATCGCATTGGCGTTGGCCGTTATGTAACGGCCTAGTAACATTTATTTGCAACTGAATAGCAAAATTCA
TTATCAATCTCACTATGAGC

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTDASADALTSPSNSGASQDTSQQNAVVLLSGGLDSVTCLYWAKARYAKVTAVSFNYGQRHNSELVAAKSIAGQAGVNHK
IIDIDIAQLGGSSLTDHDMTVPDGDADKFPTHTDDIDNQAIPNTYVPARNTIFLSYALAVAEVTDANHIVIGVSSVDYSG
YPDCRPEYIEAFEVMANLATKAGVTGHKLHIQTPLQKLSKAQTIQLGNSLGVDYSQTISCYKADSEGRACGICDSCTLRK
RGFSDAGLADPTRYAG

Sequences:

>Translated_256_residues
MTDASADALTSPSNSGASQDTSQQNAVVLLSGGLDSVTCLYWAKARYAKVTAVSFNYGQRHNSELVAAKSIAGQAGVNHK
IIDIDIAQLGGSSLTDHDMTVPDGDADKFPTHTDDIDNQAIPNTYVPARNTIFLSYALAVAEVTDANHIVIGVSSVDYSG
YPDCRPEYIEAFEVMANLATKAGVTGHKLHIQTPLQKLSKAQTIQLGNSLGVDYSQTISCYKADSEGRACGICDSCTLRK
RGFSDAGLADPTRYAG
>Mature_255_residues
TDASADALTSPSNSGASQDTSQQNAVVLLSGGLDSVTCLYWAKARYAKVTAVSFNYGQRHNSELVAAKSIAGQAGVNHKI
IDIDIAQLGGSSLTDHDMTVPDGDADKFPTHTDDIDNQAIPNTYVPARNTIFLSYALAVAEVTDANHIVIGVSSVDYSGY
PDCRPEYIEAFEVMANLATKAGVTGHKLHIQTPLQKLSKAQTIQLGNSLGVDYSQTISCYKADSEGRACGICDSCTLRKR
GFSDAGLADPTRYAG

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=238, Percent_Identity=36.1344537815126, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_PSYWF (A5WGB5)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001280656.1
- ProteinModelPortal:   A5WGB5
- SMR:   A5WGB5
- STRING:   A5WGB5
- GeneID:   5205798
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_1766
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK839057
- BioCyc:   PSP56811:PSYCPRWF_1766-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 27115; Mature: 26984

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDASADALTSPSNSGASQDTSQQNAVVLLSGGLDSVTCLYWAKARYAKVTAVSFNYGQR
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEHHCCEEEEEEEEECCCCC
HNSELVAAKSIAGQAGVNHKIIDIDIAQLGGSSLTDHDMTVPDGDADKFPTHTDDIDNQA
CCCCEEEHHHHCCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
IPNTYVPARNTIFLSYALAVAEVTDANHIVIGVSSVDYSGYPDCRPEYIEAFEVMANLAT
CCCCCCCCCCEEEEEEHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
KAGVTGHKLHIQTPLQKLSKAQTIQLGNSLGVDYSQTISCYKADSEGRACGICDSCTLRK
HCCCCCCEEEECCHHHHHHHHHEEECCCCCCCCHHHEEEEEECCCCCCEEECCCCCCHHH
RGFSDAGLADPTRYAG
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDASADALTSPSNSGASQDTSQQNAVVLLSGGLDSVTCLYWAKARYAKVTAVSFNYGQR
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEHHCCEEEEEEEEECCCCC
HNSELVAAKSIAGQAGVNHKIIDIDIAQLGGSSLTDHDMTVPDGDADKFPTHTDDIDNQA
CCCCEEEHHHHCCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
IPNTYVPARNTIFLSYALAVAEVTDANHIVIGVSSVDYSGYPDCRPEYIEAFEVMANLAT
CCCCCCCCCCEEEEEEHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
KAGVTGHKLHIQTPLQKLSKAQTIQLGNSLGVDYSQTISCYKADSEGRACGICDSCTLRK
HCCCCCCEEEECCHHHHHHHHHEEECCCCCCCCHHHEEEEEECCCCCCEEECCCCCCHHH
RGFSDAGLADPTRYAG
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA