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The map label for this gene is trpD

Identifier: 148653444

GI number: 148653444

Start: 2035861

End: 2036970

Strand: Direct

Name: trpD

Synonym: PsycPRwf_1647

Alternate gene names: 148653444

Gene position: 2035861-2036970 (Clockwise)

Preceding gene: 148653443

Following gene: 148653445

Centisome position: 68.34

GC content: 46.94

Gene sequence:

>1110_bases
ATGCCAAATACCGCCTTATCTACCGCTGAGCTGACTGATGATCAAGTTCATGACATTCTCACCACAGCCTTAGCCCGCAT
ACTCAGACGTATTGATCTAACGCAACAAGAGATGCGTCAAATTATGACCATTATTATGGATGGTCGTTGCCCTGATGCCA
TGCTAGGCGCCCTACTTACAGGGCTTAATATGAAGAGTGAGTCTATTGATGAGATTACTGCCTCTGCCAGTGTGATGCTT
GATTTTGCCAAAAAAATTGAACCAAAAAACCGCACAAATATGGTCGATATTGTTGGTACGGGAGGCGATGGCAGTAACTT
ATTTAACGTCTCTACTGCCTCAGCATTCGTGGCCGCTGCTGCAGGTGCGACTGTCGCCAAACATGGTAACCGCGGGGTAT
CATCAAAATCTGGTAGCTCAGACTTACTGGAGCAGGCAGGTCTTAATCTGAACATCACCCCAGAGCAAACGCGCGAATGT
ATTGAGACTCAAGGCATCGGCTTTTTGTTTGCACCCAATCACCATACGGCGATGAAGCATGCCATTCCCGTACGCCGAGC
TTTAAAAGTACGAACCATATTTAATATTCTAGGCCCGCTGACCAACCCAGCTGGGGTCAAAAACTTAGTGGTTGGGGTAT
TTACTGATAATATGTGTGAGCCTTTAGCACACGTATTCAAAAACTTAGGCGCCAAGCATGTGATGGTGGTCGGCTCAAAA
GATAGACTGGATGAAATCAGCCTGGCAACCAGTACCAAAGTGGCAGAATTAAAAGACGGTGAGGTTACCGTGTATGACAT
CTTCCCAGAAGATGCCGGTATTGACTCTCAGACCTTAGTCGGACTTGACGTCAACTCTTCTGAACAAAGCCTGCAACTGA
TACAAGCCGCGCTATCTGGTAAAGAGACCAATGACTTTGGTATTGCCCAAAACAAGGTCAATAAAGCGCGTGACATGATT
GCCTTAAACGCAGGCGCTGCCATCTATGTCGCCGGATTGGCCAGTAACTTCCCTAATGGGGTAAATCAGGCCCAAAACAT
CCTCCAAAGCGGTAAAGCCCTGCAAAAAATGCAGGCATTGGCTGAATATACCCAAACCTTTGATCGCTAG

Upstream 100 bases:

>100_bases
TGCAGCACAATTTATTACCAAGCTAACATCATAAGCTTGATTGTGTATAATAAATAACACCCACCCCTTTATTTCTTATC
CCAACATAGTGTTCGAACTT

Downstream 100 bases:

>100_bases
TTTTTGCTAAATTCATTATTGATAACCCTACGAGCCCAATATGACGCATGATGCCATCCCCTCAATCCTAAAAAAAATTG
TGCTGACCAAAGAGTCTGAA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MPNTALSTAELTDDQVHDILTTALARILRRIDLTQQEMRQIMTIIMDGRCPDAMLGALLTGLNMKSESIDEITASASVML
DFAKKIEPKNRTNMVDIVGTGGDGSNLFNVSTASAFVAAAAGATVAKHGNRGVSSKSGSSDLLEQAGLNLNITPEQTREC
IETQGIGFLFAPNHHTAMKHAIPVRRALKVRTIFNILGPLTNPAGVKNLVVGVFTDNMCEPLAHVFKNLGAKHVMVVGSK
DRLDEISLATSTKVAELKDGEVTVYDIFPEDAGIDSQTLVGLDVNSSEQSLQLIQAALSGKETNDFGIAQNKVNKARDMI
ALNAGAAIYVAGLASNFPNGVNQAQNILQSGKALQKMQALAEYTQTFDR

Sequences:

>Translated_369_residues
MPNTALSTAELTDDQVHDILTTALARILRRIDLTQQEMRQIMTIIMDGRCPDAMLGALLTGLNMKSESIDEITASASVML
DFAKKIEPKNRTNMVDIVGTGGDGSNLFNVSTASAFVAAAAGATVAKHGNRGVSSKSGSSDLLEQAGLNLNITPEQTREC
IETQGIGFLFAPNHHTAMKHAIPVRRALKVRTIFNILGPLTNPAGVKNLVVGVFTDNMCEPLAHVFKNLGAKHVMVVGSK
DRLDEISLATSTKVAELKDGEVTVYDIFPEDAGIDSQTLVGLDVNSSEQSLQLIQAALSGKETNDFGIAQNKVNKARDMI
ALNAGAAIYVAGLASNFPNGVNQAQNILQSGKALQKMQALAEYTQTFDR
>Mature_368_residues
PNTALSTAELTDDQVHDILTTALARILRRIDLTQQEMRQIMTIIMDGRCPDAMLGALLTGLNMKSESIDEITASASVMLD
FAKKIEPKNRTNMVDIVGTGGDGSNLFNVSTASAFVAAAAGATVAKHGNRGVSSKSGSSDLLEQAGLNLNITPEQTRECI
ETQGIGFLFAPNHHTAMKHAIPVRRALKVRTIFNILGPLTNPAGVKNLVVGVFTDNMCEPLAHVFKNLGAKHVMVVGSKD
RLDEISLATSTKVAELKDGEVTVYDIFPEDAGIDSQTLVGLDVNSSEQSLQLIQAALSGKETNDFGIAQNKVNKARDMIA
LNAGAAIYVAGLASNFPNGVNQAQNILQSGKALQKMQALAEYTQTFDR

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=284, Percent_Identity=41.9014084507042, Blast_Score=205, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6320561, Length=370, Percent_Identity=28.3783783783784, Blast_Score=119, Evalue=5e-28,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_PSYWF (A5WFZ6)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001280537.1
- ProteinModelPortal:   A5WFZ6
- SMR:   A5WFZ6
- STRING:   A5WFZ6
- GeneID:   5205655
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_1647
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- ProtClustDB:   PRK00188
- BioCyc:   PSP56811:PSYCPRWF_1647-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 39393; Mature: 39262

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTALSTAELTDDQVHDILTTALARILRRIDLTQQEMRQIMTIIMDGRCPDAMLGALLT
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
GLNMKSESIDEITASASVMLDFAKKIEPKNRTNMVDIVGTGGDGSNLFNVSTASAFVAAA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHH
AGATVAKHGNRGVSSKSGSSDLLEQAGLNLNITPEQTRECIETQGIGFLFAPNHHTAMKH
HCCHHHHCCCCCCCCCCCCHHHHHHCCCCEEECHHHHHHHHHHCCCEEEECCCCCHHHHH
AIPVRRALKVRTIFNILGPLTNPAGVKNLVVGVFTDNMCEPLAHVFKNLGAKHVMVVGSK
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEHHHHHHHHHHHHHHHCCCCEEEEECCC
DRLDEISLATSTKVAELKDGEVTVYDIFPEDAGIDSQTLVGLDVNSSEQSLQLIQAALSG
CCCHHHHHHCCCCCEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCC
KETNDFGIAQNKVNKARDMIALNAGAAIYVAGLASNFPNGVNQAQNILQSGKALQKMQAL
CCCCCCCCHHHHHHHHHHEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AEYTQTFDR
HHHHHHHCC
>Mature Secondary Structure 
PNTALSTAELTDDQVHDILTTALARILRRIDLTQQEMRQIMTIIMDGRCPDAMLGALLT
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
GLNMKSESIDEITASASVMLDFAKKIEPKNRTNMVDIVGTGGDGSNLFNVSTASAFVAAA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHH
AGATVAKHGNRGVSSKSGSSDLLEQAGLNLNITPEQTRECIETQGIGFLFAPNHHTAMKH
HCCHHHHCCCCCCCCCCCCHHHHHHCCCCEEECHHHHHHHHHHCCCEEEECCCCCHHHHH
AIPVRRALKVRTIFNILGPLTNPAGVKNLVVGVFTDNMCEPLAHVFKNLGAKHVMVVGSK
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEHHHHHHHHHHHHHHHCCCCEEEEECCC
DRLDEISLATSTKVAELKDGEVTVYDIFPEDAGIDSQTLVGLDVNSSEQSLQLIQAALSG
CCCHHHHHHCCCCCEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCC
KETNDFGIAQNKVNKARDMIALNAGAAIYVAGLASNFPNGVNQAQNILQSGKALQKMQAL
CCCCCCCCHHHHHHHHHHEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AEYTQTFDR
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA