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The map label for this gene is hscB [H]

Identifier: 148653430

GI number: 148653430

Start: 2017875

End: 2018426

Strand: Direct

Name: hscB [H]

Synonym: PsycPRwf_1632

Alternate gene names: 148653430

Gene position: 2017875-2018426 (Clockwise)

Preceding gene: 148653429

Following gene: 148653431

Centisome position: 67.74

GC content: 43.3

Gene sequence:

>552_bases
ATGTCTGATACTGCCCCTACTTTTGCCAACTTCTTCGCTTTATTTGAGCTGCCTGTTGCTTTTGACATCGATACTAACAA
GCTTAGTGAACGCTTAAGGCAACTACAAAGCCAGTTCCATCCTGACAAGCTTAGCGCTTTAGATAAAGCCTCATCAGAGC
AAAACTCTGCGGTTATCAACCATGCTTATGACATCCTGCTACACCCTGATAGCCGAGCCAATTATCTATTAGAGCTGTCC
GGTCAAGAGCTTAATACCGATCATTCTATTGCTGATTTGGATTTTTTAGATGACGCGATGGACATGCGTATGGCCTTAGA
TGATGCCGAAGCTAAAACAGATTTGCTACGTATTGAGCAGCTCAAAGTTACCGCAGATGATCGCATTGCTACCCAATCTC
AGCGTTTTATCCAAGCTTATGACCATCATGACTGGCCAATGGCGATGGATGCGACTCAAAAGCTTAAGTTTTTGGTCAAG
CTAAAAAAAGATATGGACACAGCGGTAGATAACAGCCAGCGTCAGCCAGATGATGATGACTTATATCTGTAA

Upstream 100 bases:

>100_bases
TAGTGACTGAGTTTGAGCCCTTGCTGACGACCTTGCTCGTCAGCTTTGAGCTTTTAAACCAGTATAATTCGCCTCAACCC
ACAGTAAGCATCCTAATCCT

Downstream 100 bases:

>100_bases
CATCATCTACGTATTTACTGAGCGTCTTATTTTTTGATCATGATCGTACCGACTGTGTTATTTTAAATTCTTTTATCATT
TGCTATAAATAAATTGAGTG

Product: co-chaperone Hsc20

Products: NA

Alternate protein names: Hsc20 [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSDTAPTFANFFALFELPVAFDIDTNKLSERLRQLQSQFHPDKLSALDKASSEQNSAVINHAYDILLHPDSRANYLLELS
GQELNTDHSIADLDFLDDAMDMRMALDDAEAKTDLLRIEQLKVTADDRIATQSQRFIQAYDHHDWPMAMDATQKLKFLVK
LKKDMDTAVDNSQRQPDDDDLYL

Sequences:

>Translated_183_residues
MSDTAPTFANFFALFELPVAFDIDTNKLSERLRQLQSQFHPDKLSALDKASSEQNSAVINHAYDILLHPDSRANYLLELS
GQELNTDHSIADLDFLDDAMDMRMALDDAEAKTDLLRIEQLKVTADDRIATQSQRFIQAYDHHDWPMAMDATQKLKFLVK
LKKDMDTAVDNSQRQPDDDDLYL
>Mature_182_residues
SDTAPTFANFFALFELPVAFDIDTNKLSERLRQLQSQFHPDKLSALDKASSEQNSAVINHAYDILLHPDSRANYLLELSG
QELNTDHSIADLDFLDDAMDMRMALDDAEAKTDLLRIEQLKVTADDRIATQSQRFIQAYDHHDWPMAMDATQKLKFLVKL
KKDMDTAVDNSQRQPDDDDLYL

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=164, Percent_Identity=33.5365853658537, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788876, Length=157, Percent_Identity=36.9426751592357, Blast_Score=100, Evalue=5e-23,
Organism=Drosophila melanogaster, GI161084223, Length=161, Percent_Identity=29.8136645962733, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20937; Mature: 20805

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTAPTFANFFALFELPVAFDIDTNKLSERLRQLQSQFHPDKLSALDKASSEQNSAVIN
CCCCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHH
HAYDILLHPDSRANYLLELSGQELNTDHSIADLDFLDDAMDMRMALDDAEAKTDLLRIEQ
HHEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKVTADDRIATQSQRFIQAYDHHDWPMAMDATQKLKFLVKLKKDMDTAVDNSQRQPDDDD
EEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LYL
CCC
>Mature Secondary Structure 
SDTAPTFANFFALFELPVAFDIDTNKLSERLRQLQSQFHPDKLSALDKASSEQNSAVIN
CCCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHH
HAYDILLHPDSRANYLLELSGQELNTDHSIADLDFLDDAMDMRMALDDAEAKTDLLRIEQ
HHEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKVTADDRIATQSQRFIQAYDHHDWPMAMDATQKLKFLVKLKKDMDTAVDNSQRQPDDDD
EEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LYL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA