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The map label for this gene is prmA

Identifier: 148653420

GI number: 148653420

Start: 2007599

End: 2008522

Strand: Direct

Name: prmA

Synonym: PsycPRwf_1622

Alternate gene names: 148653420

Gene position: 2007599-2008522 (Clockwise)

Preceding gene: 148653419

Following gene: 148653421

Centisome position: 67.39

GC content: 48.81

Gene sequence:

>924_bases
ATGGATTGGCAACAACTGCACCTACAATGTGCAAAACAAGACGTTGACTTGGCAGAGAGCTTATTATTAGAAGAAGGTGC
GCTTTCAATTAGCCTAGAAGATGCTGGTGACCAGCCGTTATTTGAGCCACTTCCAGGTCAGTCGCCTTTGTGGGATGAAG
TTATTTTGACCGGCCTATTTACCGCTGACACGGCACAAGACATTGAGTCTATGGCACAGACTTTGGCCGCTCAAGTCAAC
GCTCGACGTGTTTGGACCACGGCACTGGCAGACACAGACTGGGAGCGTGAATGGATGTCGCATTACGTGCCTATTGAGTG
CACCAACAACTTGTGGATTGTGCCCAAGTGGATGACCCCGCCCAATCCAGATGCGGTAAATATCATGATGGATCCAGGCT
TAGCTTTTGGTACTGGCTATCACGCCACCACACGTCTTTGCTTAGATTGGCTCACTGATCAAGACTTAAGCGATAAAGTC
ATTATCGACTATGGCTGCGGCTCAGGTATCTTAGGCATTGCCGCCTTATTACTGGGCGCCAAGCAAGTGTACAGCGTAGA
CATCGATCCACAAGCGGTACTGGCCACTAAGCAGAACGCTGAGCGTAATGATGTCACCCATGCTCTTGAGGTGTATCTGC
CAGAGGATTTTGCCAAAGCCTTTGCTGCCGGTGATATCCCAAAAGCGGATATTATTACCGCCAATATCTTAGCCAAGCCT
TTAATGGAATTGGCACCCTATTTAGCCACTTTAATTAAGCCGAAAGGGGGTATCGTGCTGGCCGGACTTATCTCAGAGCA
GCTTGAGGATATGGTCCGCGCGTATGAGCCTTGGTTCAATCTAGATACCCGCCACTCTTATGAAAAAAGTGATGATCATG
ATGACTCGCACTGGCACCGTTTATCAGGCACCTTTACAGGCTAA

Upstream 100 bases:

>100_bases
AACGAGGCAAAAGCGGCTCTTTCAAGATAACCCCTATCAACACAGACGCTATCAAGCTAAAATAGAGCGTTTTATTAAAC
CGATTTATCTAAGGACACTT

Downstream 100 bases:

>100_bases
AAACACAGCCCAGTAACTATCAAAAGCACAGCTGCAAAAGTAAGCAGCTGTGCAAATTTAACCACTCTCACGCTTTTTAA
CCTTCATTGTACAGACTTAA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDWQQLHLQCAKQDVDLAESLLLEEGALSISLEDAGDQPLFEPLPGQSPLWDEVILTGLFTADTAQDIESMAQTLAAQVN
ARRVWTTALADTDWEREWMSHYVPIECTNNLWIVPKWMTPPNPDAVNIMMDPGLAFGTGYHATTRLCLDWLTDQDLSDKV
IIDYGCGSGILGIAALLLGAKQVYSVDIDPQAVLATKQNAERNDVTHALEVYLPEDFAKAFAAGDIPKADIITANILAKP
LMELAPYLATLIKPKGGIVLAGLISEQLEDMVRAYEPWFNLDTRHSYEKSDDHDDSHWHRLSGTFTG

Sequences:

>Translated_307_residues
MDWQQLHLQCAKQDVDLAESLLLEEGALSISLEDAGDQPLFEPLPGQSPLWDEVILTGLFTADTAQDIESMAQTLAAQVN
ARRVWTTALADTDWEREWMSHYVPIECTNNLWIVPKWMTPPNPDAVNIMMDPGLAFGTGYHATTRLCLDWLTDQDLSDKV
IIDYGCGSGILGIAALLLGAKQVYSVDIDPQAVLATKQNAERNDVTHALEVYLPEDFAKAFAAGDIPKADIITANILAKP
LMELAPYLATLIKPKGGIVLAGLISEQLEDMVRAYEPWFNLDTRHSYEKSDDHDDSHWHRLSGTFTG
>Mature_307_residues
MDWQQLHLQCAKQDVDLAESLLLEEGALSISLEDAGDQPLFEPLPGQSPLWDEVILTGLFTADTAQDIESMAQTLAAQVN
ARRVWTTALADTDWEREWMSHYVPIECTNNLWIVPKWMTPPNPDAVNIMMDPGLAFGTGYHATTRLCLDWLTDQDLSDKV
IIDYGCGSGILGIAALLLGAKQVYSVDIDPQAVLATKQNAERNDVTHALEVYLPEDFAKAFAAGDIPKADIITANILAKP
LMELAPYLATLIKPKGGIVLAGLISEQLEDMVRAYEPWFNLDTRHSYEKSDDHDDSHWHRLSGTFTG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=306, Percent_Identity=43.7908496732026, Blast_Score=222, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_PSYWF (A5WFX2)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001280513.1
- ProteinModelPortal:   A5WFX2
- SMR:   A5WFX2
- STRING:   A5WFX2
- GeneID:   5206488
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_1622
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- ProtClustDB:   PRK00517
- BioCyc:   PSP56811:PSYCPRWF_1622-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34006; Mature: 34006

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWQQLHLQCAKQDVDLAESLLLEEGALSISLEDAGDQPLFEPLPGQSPLWDEVILTGLF
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
TADTAQDIESMAQTLAAQVNARRVWTTALADTDWEREWMSHYVPIECTNNLWIVPKWMTP
CCCHHHHHHHHHHHHHHHHCCHHEEEHHHCCCCHHHHHHHCCCCEEECCCEEEEEECCCC
PNPDAVNIMMDPGLAFGTGYHATTRLCLDWLTDQDLSDKVIIDYGCGSGILGIAALLLGA
CCCCEEEEEECCCCEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCC
KQVYSVDIDPQAVLATKQNAERNDVTHALEVYLPEDFAKAFAAGDIPKADIITANILAKP
HHEEEECCCCCEEEEECCCCCHHHHHHHHHEECCHHHHHHHHCCCCCCHHHEEHHHHHHH
LMELAPYLATLIKPKGGIVLAGLISEQLEDMVRAYEPWFNLDTRHSYEKSDDHDDSHWHR
HHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHEE
LSGTFTG
CCCCCCC
>Mature Secondary Structure
MDWQQLHLQCAKQDVDLAESLLLEEGALSISLEDAGDQPLFEPLPGQSPLWDEVILTGLF
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
TADTAQDIESMAQTLAAQVNARRVWTTALADTDWEREWMSHYVPIECTNNLWIVPKWMTP
CCCHHHHHHHHHHHHHHHHCCHHEEEHHHCCCCHHHHHHHCCCCEEECCCEEEEEECCCC
PNPDAVNIMMDPGLAFGTGYHATTRLCLDWLTDQDLSDKVIIDYGCGSGILGIAALLLGA
CCCCEEEEEECCCCEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCC
KQVYSVDIDPQAVLATKQNAERNDVTHALEVYLPEDFAKAFAAGDIPKADIITANILAKP
HHEEEECCCCCEEEEECCCCCHHHHHHHHHEECCHHHHHHHHCCCCCCHHHEEHHHHHHH
LMELAPYLATLIKPKGGIVLAGLISEQLEDMVRAYEPWFNLDTRHSYEKSDDHDDSHWHR
HHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHEE
LSGTFTG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA