Click here to switch to the map view.

The map label for this gene is lplT [H]

Identifier: 148653406

GI number: 148653406

Start: 1986547

End: 1987866

Strand: Direct

Name: lplT [H]

Synonym: PsycPRwf_1608

Alternate gene names: 148653406

Gene position: 1986547-1987866 (Clockwise)

Preceding gene: 148653403

Following gene: 148653408

Centisome position: 66.69

GC content: 41.36

Gene sequence:

>1320_bases
ATGGCATCACAATTTACCCTGTTTCGCAGTCGCCGCTTTACGCCGATGTTTTTTACCCAATTTTTGGGTGCTTTTAATGA
TAACTTTTTTAAACAAGCGCTGCTTTTGGTTCTAACCTATAGTGCAGCGGCCAAGTTAGGTGCCTCAGTTAGTTTACTGA
ACAATTTGGCCGCCATGTTGTTTATTTTGCCTTTTTTCTTATTTTCTGCCCTAGCAGGACAATTGGCCGATAAATATGAA
AAGTCACGCCTAACTTGGTATATCAAAGTGTTAGAAGTGGTCATTATGCTACTGGCCGCTTTTGGGCTGATTTTTGAAAT
TTATTGGCTGCTATTTTTGGCGCTATTTTTATTAGGTGCCCAGTCCACTTTCTTTGGCCCCATTAAATACGCTTATTTGC
CTCAAGCGATGCAAAAAGATGAGCTGGTCGGTGCCAATGGCCTGTTTCAAACCGGCACGTCCCTGTCGATCCTAACCGGT
ATGATGTTTGCCGGCTTATTTACCCAAATGGAAAACCATTTGTATTGGGTCAGTGCCATGGCGTTACTGATTGCCGCTTT
GGGCTTGTTGGCCGCCAAATTTATTCCAAGAATGCCTGCCGTACAGCCTGACTTAAAAGTGAACTGGAATATCTTTAGCA
CCAGTATGGACACCATTAAGTATCTGTATTCGCTGCCATTGTTGTTTTTTATCATCTTAGGTAACAGCTGGTTTTGGTTC
TATGGCGCTACCTTTTTGACCCAGACTCCTGAGTTTAGTAAGGTTATTTTACAAGGCAATGAATCTGTGGTTATCTTTTT
ACTCACCTTATTCTCAGTGGGGGTCGCTTCAGGGTCTTTGTTATGTAAAACATTGACCAAAAATCAGGTGAGCTTTAAGT
TACTGCCCTTTGGTATCGCAGGGCTCAGCCTATTTGCCATAGATTTATATTTTTCGTTATCTGCACTTACTATCAGTACT
GGCAGCTTATTAGGTATTGCGGAGTTGTCTGAGGTGAGCGGTAGCTTTCGGGTATTTGCAGATCTATTTTTCTTAGGCTT
TAGTGGCGGTATTTATATTGTGCCTTTGTATGCGGCGATGCAGGCTTACTCACCTATTAGTCACAGGGCGCGAGTCATTG
GCGCCAACAATATCTTTAATGCCATTTTTATGGTCAGCTCCGCCATCTTTTCTATCGTGATTTTAAATCTATTAAAAATG
CCTTTGCCGCAGCTGTTCTTAGTGACGGGTATCTTAAATATCTTATTTGGGATAATGCTATATTTTAAATTAAAAAAATA
TCAAGGCACCCTGAGTATTCAAGAAGACGCGCTTATCTAA

Upstream 100 bases:

>100_bases
TGAACATAATTATCAGTGAAAAATTATCGCTCAAATCTTGATGAATACTATGAGCTATTTGAGATAGCCACTATTTTGTA
CTTATATTAGGAAGCCGCAT

Downstream 100 bases:

>100_bases
ACGCACAAAGCGTTCACAACCACACACATTAGAGATTTAAGCGAGCCGCTGCTTTGACGTGGTAAACCATAAAAAAGCCA
ACCTTTAACAATAAAGGTTG

Product: major facilitator transporter

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MASQFTLFRSRRFTPMFFTQFLGAFNDNFFKQALLLVLTYSAAAKLGASVSLLNNLAAMLFILPFFLFSALAGQLADKYE
KSRLTWYIKVLEVVIMLLAAFGLIFEIYWLLFLALFLLGAQSTFFGPIKYAYLPQAMQKDELVGANGLFQTGTSLSILTG
MMFAGLFTQMENHLYWVSAMALLIAALGLLAAKFIPRMPAVQPDLKVNWNIFSTSMDTIKYLYSLPLLFFIILGNSWFWF
YGATFLTQTPEFSKVILQGNESVVIFLLTLFSVGVASGSLLCKTLTKNQVSFKLLPFGIAGLSLFAIDLYFSLSALTIST
GSLLGIAELSEVSGSFRVFADLFFLGFSGGIYIVPLYAAMQAYSPISHRARVIGANNIFNAIFMVSSAIFSIVILNLLKM
PLPQLFLVTGILNILFGIMLYFKLKKYQGTLSIQEDALI

Sequences:

>Translated_439_residues
MASQFTLFRSRRFTPMFFTQFLGAFNDNFFKQALLLVLTYSAAAKLGASVSLLNNLAAMLFILPFFLFSALAGQLADKYE
KSRLTWYIKVLEVVIMLLAAFGLIFEIYWLLFLALFLLGAQSTFFGPIKYAYLPQAMQKDELVGANGLFQTGTSLSILTG
MMFAGLFTQMENHLYWVSAMALLIAALGLLAAKFIPRMPAVQPDLKVNWNIFSTSMDTIKYLYSLPLLFFIILGNSWFWF
YGATFLTQTPEFSKVILQGNESVVIFLLTLFSVGVASGSLLCKTLTKNQVSFKLLPFGIAGLSLFAIDLYFSLSALTIST
GSLLGIAELSEVSGSFRVFADLFFLGFSGGIYIVPLYAAMQAYSPISHRARVIGANNIFNAIFMVSSAIFSIVILNLLKM
PLPQLFLVTGILNILFGIMLYFKLKKYQGTLSIQEDALI
>Mature_438_residues
ASQFTLFRSRRFTPMFFTQFLGAFNDNFFKQALLLVLTYSAAAKLGASVSLLNNLAAMLFILPFFLFSALAGQLADKYEK
SRLTWYIKVLEVVIMLLAAFGLIFEIYWLLFLALFLLGAQSTFFGPIKYAYLPQAMQKDELVGANGLFQTGTSLSILTGM
MFAGLFTQMENHLYWVSAMALLIAALGLLAAKFIPRMPAVQPDLKVNWNIFSTSMDTIKYLYSLPLLFFIILGNSWFWFY
GATFLTQTPEFSKVILQGNESVVIFLLTLFSVGVASGSLLCKTLTKNQVSFKLLPFGIAGLSLFAIDLYFSLSALTISTG
SLLGIAELSEVSGSFRVFADLFFLGFSGGIYIVPLYAAMQAYSPISHRARVIGANNIFNAIFMVSSAIFSIVILNLLKMP
LPQLFLVTGILNILFGIMLYFKLKKYQGTLSIQEDALI

Specific function: Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family [H]

Homologues:

Organism=Escherichia coli, GI1789200, Length=372, Percent_Identity=25.2688172043011, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: 2.3.1.51

Molecular weight: Translated: 48769; Mature: 48638

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCEECCCCCCC
>Mature Secondary Structure 
ASQFTLFRSRRFTPMFFTQFLGAFNDNFFKQALLLVLTYSAAAKLGASVSLLNNLAAML
CCCHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
FILPFFLFSALAGQLADKYEKSRLTWYIKVLEVVIMLLAAFGLIFEIYWLLFLALFLLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSTFFGPIKYAYLPQAMQKDELVGANGLFQTGTSLSILTGMMFAGLFTQMENHLYWVSAM
CCHHCCCHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLIAALGLLAAKFIPRMPAVQPDLKVNWNIFSTSMDTIKYLYSLPLLFFIILGNSWFWF
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEH
YGATFLTQTPEFSKVILQGNESVVIFLLTLFSVGVASGSLLCKTLTKNQVSFKLLPFGIA
HHHHHHCCCCCHHHHEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECHHHH
GLSLFAIDLYFSLSALTISTGSLLGIAELSEVSGSFRVFADLFFLGFSGGIYIVPLYAAM
HHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHH
QAYSPISHRARVIGANNIFNAIFMVSSAIFSIVILNLLKMPLPQLFLVTGILNILFGIML
HHCCCHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
YFKLKKYQGTLSIQEDALI
HHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]