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The map label for this gene is pcaR [H]

Identifier: 148653335

GI number: 148653335

Start: 1880460

End: 1881407

Strand: Direct

Name: pcaR [H]

Synonym: PsycPRwf_1537

Alternate gene names: 148653335

Gene position: 1880460-1881407 (Clockwise)

Preceding gene: 148653332

Following gene: 148653338

Centisome position: 63.12

GC content: 47.78

Gene sequence:

>948_bases
ATGACACACCCCAAAAAGCAACCAAATGGCTTAGATATAGCTGCTGCCTCAGATCAGTCTGGCAGCGATCATGACCCACG
CTTTTATAAAGAAACAGTATCTAATAAAGACATAGCATCTTTGCCGACCCTAAAACCATCAGCAAATATTGGTCTACTTG
ACAGCCTCAGCCGCAGTTTAGAGCATGCCAAAATAACGGATGACAAGGCCTTTATTACAGCACTTGGACGAGGACTGCTG
TTGCTAAGTGCCTTTGAAGATGAGCAAGAGCTGACCCATCAGAGGCTGTGTGATAAGACTGCTTTGCCTAAAGCCACTGT
CAGCCGCCTATTGCATACGTTGCAGCAGTTAAACTTTATCAAGCGTAATAGCAATGACAGCTATAAGCTTGGCAAAAACC
TGCTCAAATTAAGCAGCAGTGTCTGGCAAGGGCAAGATATCGTTGAAGAGGCGATGCCGTTACTGCGAGAGTTTGCACTC
ACTCATCAGGTATCGGTCAATATTGCGACCGAAGATGAGGGCGAGATGCGTTATGTGGCGTGTTATCGCAGTCCAGCACG
ATTGGCGGTGAATCTTTCAGTGGGGTCAACGGTGCCACTTGAGAAGACGGCTTTAGGGCGGGCTTATTATGCTGCGATGA
CGCCATCTATGCAGCAGCAAGTGATAGATACTCTGCCCTATGCTGATGACTCTGAGCAACAGCTTGTGGCAATAAATAGG
CTTAATCAGGCAGCTGATTTTTATCACCAGCACGGCTACAGCTTGTCCGATGGGGAGTATTCACCCGATATCTTGGCAGT
GGCAATGCCGCTATACGACAGCATTCAGGGTAAATACACTCACGCCTTAAATGCCAGTGTTCCAAGGGCGCTGTGGGAGG
CCGACAGCTATATCAGTTATATTGTGCCGCACCTACAGGCTTTGGCCAAACAGATTGAGTCATTGTAA

Upstream 100 bases:

>100_bases
AAGCAGTTTTGACAGCCATCGACTAAACAACTTATTATGTGGTTTATTATCAATGGTTTAACTGCTATTTAAAATAAATA
TAAGCGGCGATGACTACCTT

Downstream 100 bases:

>100_bases
ACAAAAGGGTTTTACCTTATTGATGATAAAAAAAGAGTTGCCAGACATGTCTGACAACTCTTTTTTATTCAGTCAGTAAA
AGCTTATTTAACTAAGCTGT

Product: regulatory protein IclR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTHPKKQPNGLDIAAASDQSGSDHDPRFYKETVSNKDIASLPTLKPSANIGLLDSLSRSLEHAKITDDKAFITALGRGLL
LLSAFEDEQELTHQRLCDKTALPKATVSRLLHTLQQLNFIKRNSNDSYKLGKNLLKLSSSVWQGQDIVEEAMPLLREFAL
THQVSVNIATEDEGEMRYVACYRSPARLAVNLSVGSTVPLEKTALGRAYYAAMTPSMQQQVIDTLPYADDSEQQLVAINR
LNQAADFYHQHGYSLSDGEYSPDILAVAMPLYDSIQGKYTHALNASVPRALWEADSYISYIVPHLQALAKQIESL

Sequences:

>Translated_315_residues
MTHPKKQPNGLDIAAASDQSGSDHDPRFYKETVSNKDIASLPTLKPSANIGLLDSLSRSLEHAKITDDKAFITALGRGLL
LLSAFEDEQELTHQRLCDKTALPKATVSRLLHTLQQLNFIKRNSNDSYKLGKNLLKLSSSVWQGQDIVEEAMPLLREFAL
THQVSVNIATEDEGEMRYVACYRSPARLAVNLSVGSTVPLEKTALGRAYYAAMTPSMQQQVIDTLPYADDSEQQLVAINR
LNQAADFYHQHGYSLSDGEYSPDILAVAMPLYDSIQGKYTHALNASVPRALWEADSYISYIVPHLQALAKQIESL
>Mature_314_residues
THPKKQPNGLDIAAASDQSGSDHDPRFYKETVSNKDIASLPTLKPSANIGLLDSLSRSLEHAKITDDKAFITALGRGLLL
LSAFEDEQELTHQRLCDKTALPKATVSRLLHTLQQLNFIKRNSNDSYKLGKNLLKLSSSVWQGQDIVEEAMPLLREFALT
HQVSVNIATEDEGEMRYVACYRSPARLAVNLSVGSTVPLEKTALGRAYYAAMTPSMQQQVIDTLPYADDSEQQLVAINRL
NQAADFYHQHGYSLSDGEYSPDILAVAMPLYDSIQGKYTHALNASVPRALWEADSYISYIVPHLQALAKQIESL

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=233, Percent_Identity=22.7467811158798, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788581, Length=244, Percent_Identity=22.5409836065574, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 34889; Mature: 34758

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPKKQPNGLDIAAASDQSGSDHDPRFYKETVSNKDIASLPTLKPSANIGLLDSLSRSL
CCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EHAKITDDKAFITALGRGLLLLSAFEDEQELTHQRLCDKTALPKATVSRLLHTLQQLNFI
HHHHCCCCHHHHHHHHCHHEEEHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KRNSNDSYKLGKNLLKLSSSVWQGQDIVEEAMPLLREFALTHQVSVNIATEDEGEMRYVA
HCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEEEE
CYRSPARLAVNLSVGSTVPLEKTALGRAYYAAMTPSMQQQVIDTLPYADDSEQQLVAINR
EECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHH
LNQAADFYHQHGYSLSDGEYSPDILAVAMPLYDSIQGKYTHALNASVPRALWEADSYISY
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHH
IVPHLQALAKQIESL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
THPKKQPNGLDIAAASDQSGSDHDPRFYKETVSNKDIASLPTLKPSANIGLLDSLSRSL
CCCCCCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EHAKITDDKAFITALGRGLLLLSAFEDEQELTHQRLCDKTALPKATVSRLLHTLQQLNFI
HHHHCCCCHHHHHHHHCHHEEEHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KRNSNDSYKLGKNLLKLSSSVWQGQDIVEEAMPLLREFALTHQVSVNIATEDEGEMRYVA
HCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEEEE
CYRSPARLAVNLSVGSTVPLEKTALGRAYYAAMTPSMQQQVIDTLPYADDSEQQLVAINR
EECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHH
LNQAADFYHQHGYSLSDGEYSPDILAVAMPLYDSIQGKYTHALNASVPRALWEADSYISY
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHH
IVPHLQALAKQIESL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]