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The map label for this gene is dppA [H]

Identifier: 148653324

GI number: 148653324

Start: 1865892

End: 1867526

Strand: Direct

Name: dppA [H]

Synonym: PsycPRwf_1526

Alternate gene names: 148653324

Gene position: 1865892-1867526 (Clockwise)

Preceding gene: 148653323

Following gene: 148653325

Centisome position: 62.64

GC content: 44.46

Gene sequence:

>1635_bases
ATGAAATACCCTATTTTTAAGCTTAGCCTATTAGCCGCAGCAACCATTGGTATCACCGCTTGTGGCGGTGGTGGTGATAA
AGCGGCCTCATCTGCCGGTGCTGCTGAAGGCGGCAAGACTTTAATCTACTGCTCTGAGGGTAGCCCTGCAGGCTTCGACC
CTGCTCAATATACTGCCGGCACCGATTTTGATGCCAGTGCCTATCCTATCTACAATGGCTTGGTTGAATTCAAACGTGGT
GAAACAGAGATTCAACCTGCTCTAGCAGAAAAATGGGACATCAGTGAAGACGGAAAAACCTACACCCTACATCTACGTAA
AGGGGTTAAATTTGGTAAGACTGACTTCTTCACCCCTACCCGTGACTTCAATGCTGACGATGTGGTATTTACCCTAAAGC
GTCTGACTGACCCTAATTTTGAATTTAATAAAGCATACCCAGCTGAATTTCCTTATTCAGTCGACATGGGCCTTCCTGAT
AACATTGCCAATATCGAAAAAATTGACGACTACACGGTAAAAATCACCTTAAAAGAAGTGAACGCGCCTTTCTTACAAAA
CCTTGCCATGCCGTTTGCTTATATTGACTCTGCTGAATATGCGCAGTCTTTAATGGATGCAGGTAAAGCAGCTGACTTAA
ATACCAAACCTGTGGGCACCGGTCCGTTTATCTTCAATTCATACCAAAAAGACTCACAAATTCGCTATACCAAAAACCCA
GATTATTGGAATAAAGACGACATTCACATTGATAACCTAGTTTTCGTTATCACCAAAGATTCAGCCGTACGTGCTCAAAA
AGTACAAGCGGGTGAGTGTCATGTTTCCGCCTATGCCAACCCCTCTGAGGTTGAGTCTGCTAAAGCCTCAGGTAAAGCAA
AAGTACTAGAAGAGCCAGGCTTTAACGTAGGTTATATTGCCTATAACACAGAGCGACCTGAGCTAAAAGATCCTAAAGTA
CGTGCGGCGCTTGATATGGCAATCAATAAAGACGCACTAATCGATGCTGTTTATCAAGGTGCTGGCGTAAAAACAGCCAA
TCCGATGCCACCTACTCAGTGGGGCTTTAACGATCAGCTAAAAGATGCCCCTTATGACACCGAAAAAGCCAAAGCATTAA
TGGCAGAAGCAGGTGTTAAAGGCTTTGATATTGATCTGTGGTATATGCCTGTTCAACGTCCTTATAACCCCAACGCTAAG
CTGATGGCCGAAATGCTTCAAGCTGACTGGGCAAAAATTGGGGTCAAAGCCAATTTAAAAACCTTTGAATGGGGCGAGTA
CTTAAAGCGTGCCAACAAAGGGGAACACGACATTATCCTAGCTGGCTGGACGGGCGACAATGGTGACCCTGATAACTGGT
TGGGCGTCTTATTATCTTGTGATGCCGTCAATGGCAATAACTATGCCCGCTGGTGTAACAAAGACTTTGATAAGCTGATT
ATGGATGCCCGCTCTAACACCAACCAAGAAGAGCGCATTGCTAATTACAAACAAGCTCAGGAGATTTTCAAGCAAGATCT
ACCCTGGACCACAGTGGCCAACTCAGTAGTAACGGTGTTAACCACACCGAATGTGAAGGATTATAAAATCAGTCCTTTAG
GCTCAATTCGTTTTGATGGTGTGGATGTCGAATAA

Upstream 100 bases:

>100_bases
CGGATTTGAGCGGCACCCAAAGACAGCCTGTCGGGCTTGGGCTGAATGACTCGAGAAACCCTCCGCGAGATTCAGTCAAC
TAGCGACACAGGAAGTTTTT

Downstream 100 bases:

>100_bases
TCGATTTATTCCATACCAGTAAACAACCTAACTCTATAATTTAGGTAAGACGGCTGGTTCAGAAACCTCTCTGTTCCAGC
CTTTTTTGATTTTGAGGATA

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MKYPIFKLSLLAAATIGITACGGGGDKAASSAGAAEGGKTLIYCSEGSPAGFDPAQYTAGTDFDASAYPIYNGLVEFKRG
ETEIQPALAEKWDISEDGKTYTLHLRKGVKFGKTDFFTPTRDFNADDVVFTLKRLTDPNFEFNKAYPAEFPYSVDMGLPD
NIANIEKIDDYTVKITLKEVNAPFLQNLAMPFAYIDSAEYAQSLMDAGKAADLNTKPVGTGPFIFNSYQKDSQIRYTKNP
DYWNKDDIHIDNLVFVITKDSAVRAQKVQAGECHVSAYANPSEVESAKASGKAKVLEEPGFNVGYIAYNTERPELKDPKV
RAALDMAINKDALIDAVYQGAGVKTANPMPPTQWGFNDQLKDAPYDTEKAKALMAEAGVKGFDIDLWYMPVQRPYNPNAK
LMAEMLQADWAKIGVKANLKTFEWGEYLKRANKGEHDIILAGWTGDNGDPDNWLGVLLSCDAVNGNNYARWCNKDFDKLI
MDARSNTNQEERIANYKQAQEIFKQDLPWTTVANSVVTVLTTPNVKDYKISPLGSIRFDGVDVE

Sequences:

>Translated_544_residues
MKYPIFKLSLLAAATIGITACGGGGDKAASSAGAAEGGKTLIYCSEGSPAGFDPAQYTAGTDFDASAYPIYNGLVEFKRG
ETEIQPALAEKWDISEDGKTYTLHLRKGVKFGKTDFFTPTRDFNADDVVFTLKRLTDPNFEFNKAYPAEFPYSVDMGLPD
NIANIEKIDDYTVKITLKEVNAPFLQNLAMPFAYIDSAEYAQSLMDAGKAADLNTKPVGTGPFIFNSYQKDSQIRYTKNP
DYWNKDDIHIDNLVFVITKDSAVRAQKVQAGECHVSAYANPSEVESAKASGKAKVLEEPGFNVGYIAYNTERPELKDPKV
RAALDMAINKDALIDAVYQGAGVKTANPMPPTQWGFNDQLKDAPYDTEKAKALMAEAGVKGFDIDLWYMPVQRPYNPNAK
LMAEMLQADWAKIGVKANLKTFEWGEYLKRANKGEHDIILAGWTGDNGDPDNWLGVLLSCDAVNGNNYARWCNKDFDKLI
MDARSNTNQEERIANYKQAQEIFKQDLPWTTVANSVVTVLTTPNVKDYKISPLGSIRFDGVDVE
>Mature_544_residues
MKYPIFKLSLLAAATIGITACGGGGDKAASSAGAAEGGKTLIYCSEGSPAGFDPAQYTAGTDFDASAYPIYNGLVEFKRG
ETEIQPALAEKWDISEDGKTYTLHLRKGVKFGKTDFFTPTRDFNADDVVFTLKRLTDPNFEFNKAYPAEFPYSVDMGLPD
NIANIEKIDDYTVKITLKEVNAPFLQNLAMPFAYIDSAEYAQSLMDAGKAADLNTKPVGTGPFIFNSYQKDSQIRYTKNP
DYWNKDDIHIDNLVFVITKDSAVRAQKVQAGECHVSAYANPSEVESAKASGKAKVLEEPGFNVGYIAYNTERPELKDPKV
RAALDMAINKDALIDAVYQGAGVKTANPMPPTQWGFNDQLKDAPYDTEKAKALMAEAGVKGFDIDLWYMPVQRPYNPNAK
LMAEMLQADWAKIGVKANLKTFEWGEYLKRANKGEHDIILAGWTGDNGDPDNWLGVLLSCDAVNGNNYARWCNKDFDKLI
MDARSNTNQEERIANYKQAQEIFKQDLPWTTVANSVVTVLTTPNVKDYKISPLGSIRFDGVDVE

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=523, Percent_Identity=51.8164435946463, Blast_Score=553, Evalue=1e-158,
Organism=Escherichia coli, GI1787551, Length=502, Percent_Identity=33.4661354581673, Blast_Score=314, Evalue=1e-86,
Organism=Escherichia coli, GI1787052, Length=540, Percent_Identity=28.7037037037037, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1787762, Length=510, Percent_Identity=25.6862745098039, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787495, Length=551, Percent_Identity=24.5009074410163, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789397, Length=506, Percent_Identity=24.901185770751, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87081878, Length=513, Percent_Identity=24.5614035087719, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1789887, Length=520, Percent_Identity=24.0384615384615, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60074; Mature: 60074

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYPIFKLSLLAAATIGITACGGGGDKAASSAGAAEGGKTLIYCSEGSPAGFDPAQYTAG
CCCCCHHHHHHHHHHHCEEEECCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCHHCCCC
TDFDASAYPIYNGLVEFKRGETEIQPALAEKWDISEDGKTYTLHLRKGVKFGKTDFFTPT
CCCCCCCCHHHHHHHHHCCCCCHHCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
RDFNADDVVFTLKRLTDPNFEFNKAYPAEFPYSVDMGLPDNIANIEKIDDYTVKITLKEV
CCCCCCHHEEEHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHCCCCEEEEEEEEEC
NAPFLQNLAMPFAYIDSAEYAQSLMDAGKAADLNTKPVGTGPFIFNSYQKDSQIRYTKNP
CCHHHHHHCCCHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCEEEECCC
DYWNKDDIHIDNLVFVITKDSAVRAQKVQAGECHVSAYANPSEVESAKASGKAKVLEEPG
CCCCCCCEEECCEEEEEECCCCHHHHHCCCCCEEEEECCCHHHHHHHHCCCCEEEECCCC
FNVGYIAYNTERPELKDPKVRAALDMAINKDALIDAVYQGAGVKTANPMPPTQWGFNDQL
CCEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
KDAPYDTEKAKALMAEAGVKGFDIDLWYMPVQRPYNPNAKLMAEMLQADWAKIGVKANLK
CCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEECCC
TFEWGEYLKRANKGEHDIILAGWTGDNGDPDNWLGVLLSCDAVNGNNYARWCNKDFDKLI
CCHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHEEEEEEEEECCCCCHHHHHCCCHHHHH
MDARSNTNQEERIANYKQAQEIFKQDLPWTTVANSVVTVLTTPNVKDYKISPLGSIRFDG
HHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCEEECCCCCEEECC
VDVE
CCCC
>Mature Secondary Structure
MKYPIFKLSLLAAATIGITACGGGGDKAASSAGAAEGGKTLIYCSEGSPAGFDPAQYTAG
CCCCCHHHHHHHHHHHCEEEECCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCHHCCCC
TDFDASAYPIYNGLVEFKRGETEIQPALAEKWDISEDGKTYTLHLRKGVKFGKTDFFTPT
CCCCCCCCHHHHHHHHHCCCCCHHCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
RDFNADDVVFTLKRLTDPNFEFNKAYPAEFPYSVDMGLPDNIANIEKIDDYTVKITLKEV
CCCCCCHHEEEHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHCCCCEEEEEEEEEC
NAPFLQNLAMPFAYIDSAEYAQSLMDAGKAADLNTKPVGTGPFIFNSYQKDSQIRYTKNP
CCHHHHHHCCCHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCEEEECCC
DYWNKDDIHIDNLVFVITKDSAVRAQKVQAGECHVSAYANPSEVESAKASGKAKVLEEPG
CCCCCCCEEECCEEEEEECCCCHHHHHCCCCCEEEEECCCHHHHHHHHCCCCEEEECCCC
FNVGYIAYNTERPELKDPKVRAALDMAINKDALIDAVYQGAGVKTANPMPPTQWGFNDQL
CCEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
KDAPYDTEKAKALMAEAGVKGFDIDLWYMPVQRPYNPNAKLMAEMLQADWAKIGVKANLK
CCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEECCC
TFEWGEYLKRANKGEHDIILAGWTGDNGDPDNWLGVLLSCDAVNGNNYARWCNKDFDKLI
CCHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHEEEEEEEEECCCCCHHHHHCCCHHHHH
MDARSNTNQEERIANYKQAQEIFKQDLPWTTVANSVVTVLTTPNVKDYKISPLGSIRFDG
HHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCEEECCCCCEEECC
VDVE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]