Click here to switch to the map view.

The map label for this gene is ubiB [C]

Identifier: 148653222

GI number: 148653222

Start: 1743449

End: 1744909

Strand: Direct

Name: ubiB [C]

Synonym: PsycPRwf_1420

Alternate gene names: 148653222

Gene position: 1743449-1744909 (Clockwise)

Preceding gene: 148653221

Following gene: 148653224

Centisome position: 58.53

GC content: 46.61

Gene sequence:

>1461_bases
ATGGCAAATTCATCATCCTCGATACCACCACAGCCTGAGTTACAAGCCACTACCCAAAATGAGCTAAGTGAGCTTAAAAC
CTCTCGCTTAGACCGTCGTCTATCTATGGCCAAAACCTCGTTAAATCTAGGCAGACGCTGGGCGGGTAATAGCTTTAGTG
GGCTGTTTTTAAGTAAAGAAGAAAAAGCCTCGCGCAACCAAGCCTTTATGAAAGAGCAAGCCGCTTATCTGGCAGATGAG
CTTGGCAAGCTTAAAGGCTCTGTGGTGAAGATTGGCCAAATGCTTGCCTTATATGGAGAGCATTTTTTGCATCCTGAGAT
TACCGAAGCCCTACATCGTCTCAATGACAGTACAGCAAGCTTGTCTTGGCCGGTGGTGGAGCGTGCATTAATCGAGCAGC
TGGGTCAGCAGCGTCTTAATGAGCTCGACATTAGCCGCACCCCTATTGGTACCGCCTCATTGGCACAAGTACACCGTGCC
ACTATCAAGGCCACTGGCAAACAGGTGGTGCTCAAAGTCCAGTACCCAGGTGTGGCCGATGCCATTGATTCAGACTTAAG
CTTATTTAAGCATTTGCTAAAAGTTACCAATGCTGTGCCACAGACTAAAGCATTAGATGAGTGGTTTAATGAAATCAGTG
ACCTACTAAAAGTTGAGGTGGACTATCTGGCTGAAGCCCAGACCACCATCCGCTTCTACACACGATTAAAGCAAGATGAG
CGCTATGTGGTGCCAGAGGTGATTGAGGCCTATTCTACTGCCCGCGTATTGTGCTTAAGTTTTGAGGAGGGGGTGCCGGT
CACCAATGCTAATTTAAAAGCTCTGCCGCAAGCCCGCCGTGACGCGCTAGGCAAAGCTGCCATTGACATTATGCTCAATG
AAATCTTTGTTTGGGGCGAGATGCAAACCGACCCAAACTTTGGCAATTATCTGATTCGCTCAGAGCCTGCTGATAAGCCT
GATGGCAAAGACAAACTAATTTTATTAGACTTCGGCGCCATGCGTCAGTTCGATGAGCATCTGCTTAAGATTGCCCGTAA
CTTAATGCTGGCAGGCTTTAATTATGATAAATCGCAAATGATGCAGGCCATGCAGGGCTATGAGTTCTTTGATGGTATGA
GTGCTGAGGTTAAAGCCAATATGGCTGATGTATTCTTATTGGCCACCGAGCCTTTTAGAGCGCCTAACCTGCAGCAGACG
ACCATTCCCTCGCTCGTTGATGCCCAAGGCTATTATCATTGGGCCAAAAGCAACTTACATAAGCGGTTAATGGAAAGCTC
AGGCAATGCCATGCAGTCTCGTGAATTTAGCTTACCTCCCAAAGAGTTTATGTTTATTAGTCGCAAATTTATCGGTGCTT
ACACCTTTTTAACGGTATTAGATGCACGCACCAATACTTATGATACCTTGAGTAAGTTTGTGCCAATTAACATGATTGCC
AGTGGTACCCCTAACGCTTAG

Upstream 100 bases:

>100_bases
CCATTCATGGTCTTACTAGAACCTCCCATCCTAATTACTTATATTGCCCTCTCATTGGCACACGCCACGAGATGGCTTTA
GTTTCCAATATGGTTAAAAC

Downstream 100 bases:

>100_bases
TCGTCTTATATGAGTTTAAATCGCTCATTCAAAAAGCGGCCAAATCACAAGATTTGGCCGCTTTTTTGTCAGTTTTTATC
CGCTTTATCAAAAGCAAGCT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MANSSSSIPPQPELQATTQNELSELKTSRLDRRLSMAKTSLNLGRRWAGNSFSGLFLSKEEKASRNQAFMKEQAAYLADE
LGKLKGSVVKIGQMLALYGEHFLHPEITEALHRLNDSTASLSWPVVERALIEQLGQQRLNELDISRTPIGTASLAQVHRA
TIKATGKQVVLKVQYPGVADAIDSDLSLFKHLLKVTNAVPQTKALDEWFNEISDLLKVEVDYLAEAQTTIRFYTRLKQDE
RYVVPEVIEAYSTARVLCLSFEEGVPVTNANLKALPQARRDALGKAAIDIMLNEIFVWGEMQTDPNFGNYLIRSEPADKP
DGKDKLILLDFGAMRQFDEHLLKIARNLMLAGFNYDKSQMMQAMQGYEFFDGMSAEVKANMADVFLLATEPFRAPNLQQT
TIPSLVDAQGYYHWAKSNLHKRLMESSGNAMQSREFSLPPKEFMFISRKFIGAYTFLTVLDARTNTYDTLSKFVPINMIA
SGTPNA

Sequences:

>Translated_486_residues
MANSSSSIPPQPELQATTQNELSELKTSRLDRRLSMAKTSLNLGRRWAGNSFSGLFLSKEEKASRNQAFMKEQAAYLADE
LGKLKGSVVKIGQMLALYGEHFLHPEITEALHRLNDSTASLSWPVVERALIEQLGQQRLNELDISRTPIGTASLAQVHRA
TIKATGKQVVLKVQYPGVADAIDSDLSLFKHLLKVTNAVPQTKALDEWFNEISDLLKVEVDYLAEAQTTIRFYTRLKQDE
RYVVPEVIEAYSTARVLCLSFEEGVPVTNANLKALPQARRDALGKAAIDIMLNEIFVWGEMQTDPNFGNYLIRSEPADKP
DGKDKLILLDFGAMRQFDEHLLKIARNLMLAGFNYDKSQMMQAMQGYEFFDGMSAEVKANMADVFLLATEPFRAPNLQQT
TIPSLVDAQGYYHWAKSNLHKRLMESSGNAMQSREFSLPPKEFMFISRKFIGAYTFLTVLDARTNTYDTLSKFVPINMIA
SGTPNA
>Mature_485_residues
ANSSSSIPPQPELQATTQNELSELKTSRLDRRLSMAKTSLNLGRRWAGNSFSGLFLSKEEKASRNQAFMKEQAAYLADEL
GKLKGSVVKIGQMLALYGEHFLHPEITEALHRLNDSTASLSWPVVERALIEQLGQQRLNELDISRTPIGTASLAQVHRAT
IKATGKQVVLKVQYPGVADAIDSDLSLFKHLLKVTNAVPQTKALDEWFNEISDLLKVEVDYLAEAQTTIRFYTRLKQDER
YVVPEVIEAYSTARVLCLSFEEGVPVTNANLKALPQARRDALGKAAIDIMLNEIFVWGEMQTDPNFGNYLIRSEPADKPD
GKDKLILLDFGAMRQFDEHLLKIARNLMLAGFNYDKSQMMQAMQGYEFFDGMSAEVKANMADVFLLATEPFRAPNLQQTT
IPSLVDAQGYYHWAKSNLHKRLMESSGNAMQSREFSLPPKEFMFISRKFIGAYTFLTVLDARTNTYDTLSKFVPINMIAS
GTPNA

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI27363457, Length=404, Percent_Identity=26.4851485148515, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI34147522, Length=391, Percent_Identity=26.3427109974425, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI217416386, Length=370, Percent_Identity=26.2162162162162, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI40254938, Length=269, Percent_Identity=30.4832713754647, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI41393593, Length=258, Percent_Identity=31.7829457364341, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI217035081, Length=205, Percent_Identity=32.6829268292683, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI2367309, Length=279, Percent_Identity=24.0143369175627, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI32565180, Length=413, Percent_Identity=27.8450363196126, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17559152, Length=280, Percent_Identity=32.5, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321319, Length=395, Percent_Identity=28.1012658227848, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6323282, Length=324, Percent_Identity=24.6913580246914, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI18859849, Length=397, Percent_Identity=27.9596977329975, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI22024280, Length=286, Percent_Identity=27.972027972028, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24662575, Length=255, Percent_Identity=27.843137254902, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 54524; Mature: 54393

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSSSSIPPQPELQATTQNELSELKTSRLDRRLSMAKTSLNLGRRWAGNSFSGLFLSKE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCH
EKASRNQAFMKEQAAYLADELGKLKGSVVKIGQMLALYGEHFLHPEITEALHRLNDSTAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
LSWPVVERALIEQLGQQRLNELDISRTPIGTASLAQVHRATIKATGKQVVLKVQYPGVAD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHH
AIDSDLSLFKHLLKVTNAVPQTKALDEWFNEISDLLKVEVDYLAEAQTTIRFYTRLKQDE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RYVVPEVIEAYSTARVLCLSFEEGVPVTNANLKALPQARRDALGKAAIDIMLNEIFVWGE
CEEHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHEEEEE
MQTDPNFGNYLIRSEPADKPDGKDKLILLDFGAMRQFDEHLLKIARNLMLAGFNYDKSQM
CCCCCCCCCEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MQAMQGYEFFDGMSAEVKANMADVFLLATEPFRAPNLQQTTIPSLVDAQGYYHWAKSNLH
HHHHHCCHHHCCCCHHHHCCCEEEEEEECCCCCCCCCCHHCCCHHHHCCCHHHHHHHHHH
KRLMESSGNAMQSREFSLPPKEFMFISRKFIGAYTFLTVLDARTNTYDTLSKFVPINMIA
HHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEE
SGTPNA
CCCCCC
>Mature Secondary Structure 
ANSSSSIPPQPELQATTQNELSELKTSRLDRRLSMAKTSLNLGRRWAGNSFSGLFLSKE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCH
EKASRNQAFMKEQAAYLADELGKLKGSVVKIGQMLALYGEHFLHPEITEALHRLNDSTAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
LSWPVVERALIEQLGQQRLNELDISRTPIGTASLAQVHRATIKATGKQVVLKVQYPGVAD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHH
AIDSDLSLFKHLLKVTNAVPQTKALDEWFNEISDLLKVEVDYLAEAQTTIRFYTRLKQDE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RYVVPEVIEAYSTARVLCLSFEEGVPVTNANLKALPQARRDALGKAAIDIMLNEIFVWGE
CEEHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHEEEEE
MQTDPNFGNYLIRSEPADKPDGKDKLILLDFGAMRQFDEHLLKIARNLMLAGFNYDKSQM
CCCCCCCCCEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MQAMQGYEFFDGMSAEVKANMADVFLLATEPFRAPNLQQTTIPSLVDAQGYYHWAKSNLH
HHHHHCCHHHCCCCHHHHCCCEEEEEEECCCCCCCCCCHHCCCHHHHCCCHHHHHHHHHH
KRLMESSGNAMQSREFSLPPKEFMFISRKFIGAYTFLTVLDARTNTYDTLSKFVPINMIA
HHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEE
SGTPNA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]