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The map label for this gene is erg3 [H]

Identifier: 148653010

GI number: 148653010

Start: 1474076

End: 1475023

Strand: Direct

Name: erg3 [H]

Synonym: PsycPRwf_1204

Alternate gene names: 148653010

Gene position: 1474076-1475023 (Clockwise)

Preceding gene: 148653009

Following gene: 148653011

Centisome position: 49.48

GC content: 44.09

Gene sequence:

>948_bases
ATGAATGGAATCACGGAGCAGTTAAATGCTCTAAAAGACACATTAAATGATGGTGTTTTAACTATCGCTCCTGAAGCCAT
ACACCCTACTTTGGTGAGTATATTGCCCCAACACTGGCAGGAGTGGTTATTGCCTTTAATGGGTGGGCCCTTTGTTTTGA
TATTTCTACTTGAGTGGTTTTATCAAAGCCGCCGCGGGCAAGCTGAACAATTTTCAGCCAAAAGAGCCCTGACTAACTTT
AGCTTAGGCGGCACCTACATCACCTTTGAGCTGATTATTCAGGCGTTGATAGTGCTGCCAATTTGCTTGTGGTTGTATCA
ATTTCGGTTATTTACCATTGATGTCACTTGGCTTAGTGCCCTGCCTATCTTTATTGCCGTTGAGTTTTGTTATTACTGGT
TCCACCGCGCCTCGCACCGGATCAGCTGGTTTTGGTCGGCACACATAGTGCATCACACTGATGATCGTATGAATTTATCG
ACTGCCATGCGCCAAAGCTTACTGTATTCGGTTACCGGTTGGTGGCTGTTTTTTACCCCGCTGATGCTGCTAGGCGTGCA
TCCGGTCTGGGTGTTCTTCTTCTACGCGCTTGATTTAATTTATCAATTCTTCATTCATACCGAAACTGTCGGCAAGCTCC
CTAAATGGGTGGAATATGTCTTTGATACCCCCTCTAACCATAGAGCCCATCATGGCACCAATGCCGCTTATGTCGATAAA
AACTATGGCGGCGTACTGATTATTTTTGACCGCTTATTTGGTACTTATGTTGAAGAAGACCCCCTCAATAATCCTGTACG
ATTTGGCGCTTATGGTGAGAAAAGCAATGACAACCTCTTTGGGCTGATATTTTCTTTTTTTGGTCGCATGTGGCACAAAG
CTTTAAGCGCTCAAGGGCTAAAACAAAAACTAAAAGCCTTTATTCATCCCCCCAGTGAGATAAAATAA

Upstream 100 bases:

>100_bases
GGGTTGCCTCCCTGATAACTGCTAAACTCAGAGAGATACTTGTGCTTAACGCCGTTATCTTTCACAGCGACGTCATATTT
AACAAGGTAGTGAGGTAACT

Downstream 100 bases:

>100_bases
CAAAACAAGCGACACTGCTAACTTGGTAAACGTATTTTTCGCTTTGATGTTTACTGTGATTTATACTATTAATTTGATCA
ATATTTGAGTCCTTTATGAC

Product: sterol desaturase-like protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNGITEQLNALKDTLNDGVLTIAPEAIHPTLVSILPQHWQEWLLPLMGGPFVLIFLLEWFYQSRRGQAEQFSAKRALTNF
SLGGTYITFELIIQALIVLPICLWLYQFRLFTIDVTWLSALPIFIAVEFCYYWFHRASHRISWFWSAHIVHHTDDRMNLS
TAMRQSLLYSVTGWWLFFTPLMLLGVHPVWVFFFYALDLIYQFFIHTETVGKLPKWVEYVFDTPSNHRAHHGTNAAYVDK
NYGGVLIIFDRLFGTYVEEDPLNNPVRFGAYGEKSNDNLFGLIFSFFGRMWHKALSAQGLKQKLKAFIHPPSEIK

Sequences:

>Translated_315_residues
MNGITEQLNALKDTLNDGVLTIAPEAIHPTLVSILPQHWQEWLLPLMGGPFVLIFLLEWFYQSRRGQAEQFSAKRALTNF
SLGGTYITFELIIQALIVLPICLWLYQFRLFTIDVTWLSALPIFIAVEFCYYWFHRASHRISWFWSAHIVHHTDDRMNLS
TAMRQSLLYSVTGWWLFFTPLMLLGVHPVWVFFFYALDLIYQFFIHTETVGKLPKWVEYVFDTPSNHRAHHGTNAAYVDK
NYGGVLIIFDRLFGTYVEEDPLNNPVRFGAYGEKSNDNLFGLIFSFFGRMWHKALSAQGLKQKLKAFIHPPSEIK
>Mature_315_residues
MNGITEQLNALKDTLNDGVLTIAPEAIHPTLVSILPQHWQEWLLPLMGGPFVLIFLLEWFYQSRRGQAEQFSAKRALTNF
SLGGTYITFELIIQALIVLPICLWLYQFRLFTIDVTWLSALPIFIAVEFCYYWFHRASHRISWFWSAHIVHHTDDRMNLS
TAMRQSLLYSVTGWWLFFTPLMLLGVHPVWVFFFYALDLIYQFFIHTETVGKLPKWVEYVFDTPSNHRAHHGTNAAYVDK
NYGGVLIIFDRLFGTYVEEDPLNNPVRFGAYGEKSNDNLFGLIFSFFGRMWHKALSAQGLKQKLKAFIHPPSEIK

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=145, Percent_Identity=46.2068965517241, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI25144659, Length=280, Percent_Identity=30.3571428571429, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 36706; Mature: 36706

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGITEQLNALKDTLNDGVLTIAPEAIHPTLVSILPQHWQEWLLPLMGGPFVLIFLLEWF
CCCHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
YQSRRGQAEQFSAKRALTNFSLGGTYITFELIIQALIVLPICLWLYQFRLFTIDVTWLSA
HHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHH
LPIFIAVEFCYYWFHRASHRISWFWSAHIVHHTDDRMNLSTAMRQSLLYSVTGWWLFFTP
HHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMLLGVHPVWVFFFYALDLIYQFFIHTETVGKLPKWVEYVFDTPSNHRAHHGTNAAYVDK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEC
NYGGVLIIFDRLFGTYVEEDPLNNPVRFGAYGEKSNDNLFGLIFSFFGRMWHKALSAQGL
CCCCEEEEHHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KQKLKAFIHPPSEIK
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MNGITEQLNALKDTLNDGVLTIAPEAIHPTLVSILPQHWQEWLLPLMGGPFVLIFLLEWF
CCCHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
YQSRRGQAEQFSAKRALTNFSLGGTYITFELIIQALIVLPICLWLYQFRLFTIDVTWLSA
HHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHH
LPIFIAVEFCYYWFHRASHRISWFWSAHIVHHTDDRMNLSTAMRQSLLYSVTGWWLFFTP
HHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMLLGVHPVWVFFFYALDLIYQFFIHTETVGKLPKWVEYVFDTPSNHRAHHGTNAAYVDK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEC
NYGGVLIIFDRLFGTYVEEDPLNNPVRFGAYGEKSNDNLFGLIFSFFGRMWHKALSAQGL
CCCCEEEEHHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KQKLKAFIHPPSEIK
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]