Click here to switch to the map view.

The map label for this gene is yfcX [C]

Identifier: 148652889

GI number: 148652889

Start: 1306463

End: 1307734

Strand: Direct

Name: yfcX [C]

Synonym: PsycPRwf_1082

Alternate gene names: 148652889

Gene position: 1306463-1307734 (Clockwise)

Preceding gene: 148652888

Following gene: 148652890

Centisome position: 43.86

GC content: 47.96

Gene sequence:

>1272_bases
ATGGTCATTGCTGTTATCTTTTTTATTTATAAAATTATTGAAACTGGGGCAAATATTGACATGCAATTTAATGATAAAAG
TGAAGCAGCTCAGGGCATAATGGCTGCTGATAGCGAAGAAGTGGTATTTGAACGCATCCAAATTAAGCAAGGCCTAATCA
TCGGCTTGGTGCGCTTAAACCGTGAAAAATCGCTCAATGCGTTAAGCACTCACATGTGCAAGCTAATAAGCGCACAGCTG
ACACAGTGGGAGAAGCTTGATAATCTTGTGGCAGTGGTGATACGCGGGGCAGGCGAGCGCGCATTATGTGCCGGTGGCGA
TATCCGTCAGTTGTATCAAGCTCGCCAGCAGTGGGATAAAGAGTGCATGGCGCCGCCAGAGGCCATTGATTTTTTCGCCA
GTGAGTATCATTTAGACACTCAAATGCATGAGTATCACAAGCCCATTATTATCTGGGGCAGCGGTATTGTGATGGGCGGC
GGCATGGGGTTATTAAGCAGTAGCAGCCACCGCATTGTGACCGAGACCACCCGTGCGGCGATGCCAGAGGTGAATATCGG
CCTGTTTCCTGATGCGACAGGCAGCTGGTTTTTACAACGATTTCCTGCCAAGACCGGTCTGTTTATGGGCTTGACCGGTG
CGGACGCCAACGCCAATGACGCACTGCTGTGTAATTTGGCTGATTTTAAAATGAGCAGCCAACACTTTGATGCCATGCTG
CAAAGCTTATGTGAGGCAGATTGGCGCGAGGCTTTGGGTCAACCCACTCTAAATAGCCTAAGCAGTAAGCTGCATCAAAT
CACAACCAAAACCCTCAGCGAGTTTAGCAAGCAATCTGTTAAAAGCGTCGAATTTGCACCAAGCAATATTGCTAAGTTTA
TGGTGCCGATACAGCACTTAATGAGCTGTGGCGGTCTGGATAAAATTGATGCTATTTTGCAGTCGGACTCGGCCATTGAG
CAGTTTTATCCAGAGTTTGCCAGCAGTGCGTGGTTTCAGGCGGCCGTGGGGAATTATCGCTATGGTTGTCCGGTGACCAA
AGCCATTACTTACGAGATGTATCAGCGAGCCCACAACTTATCATTAGCCGAAATTATGGCACTTGAAACCAATGTGGCGC
TGCACTGCGTCAACTATCCTGACTTTAGTGAAGGGGTGCGTGCTTTACTGATAGACAAAGACCGCAAGCCGCAGTGGAGT
CGCAGCCTAGCTGAGTGTTTAGATATTGAAGGTCAAGCCTACATTCAACAACACTTTCAAGCGCTATCCTAG

Upstream 100 bases:

>100_bases
GCCCCCTTATGAAAAATAGGTGTGATAATGGGCAAATGTCACACCCACTAAGGATAAAGCAAGCACAGGCATCAAGGCCA
TAAGCCGATTAATTGTGCTT

Downstream 100 bases:

>100_bases
GTTTTTCAGCCTGACACGACATGATGTGTCATTTACGCCTATAAAAATTTTATACGAGACAAGATATGAGCAAGGCAGGC
TTCAGCGCTGCCTTGCTTTT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MVIAVIFFIYKIIETGANIDMQFNDKSEAAQGIMAADSEEVVFERIQIKQGLIIGLVRLNREKSLNALSTHMCKLISAQL
TQWEKLDNLVAVVIRGAGERALCAGGDIRQLYQARQQWDKECMAPPEAIDFFASEYHLDTQMHEYHKPIIIWGSGIVMGG
GMGLLSSSSHRIVTETTRAAMPEVNIGLFPDATGSWFLQRFPAKTGLFMGLTGADANANDALLCNLADFKMSSQHFDAML
QSLCEADWREALGQPTLNSLSSKLHQITTKTLSEFSKQSVKSVEFAPSNIAKFMVPIQHLMSCGGLDKIDAILQSDSAIE
QFYPEFASSAWFQAAVGNYRYGCPVTKAITYEMYQRAHNLSLAEIMALETNVALHCVNYPDFSEGVRALLIDKDRKPQWS
RSLAECLDIEGQAYIQQHFQALS

Sequences:

>Translated_423_residues
MVIAVIFFIYKIIETGANIDMQFNDKSEAAQGIMAADSEEVVFERIQIKQGLIIGLVRLNREKSLNALSTHMCKLISAQL
TQWEKLDNLVAVVIRGAGERALCAGGDIRQLYQARQQWDKECMAPPEAIDFFASEYHLDTQMHEYHKPIIIWGSGIVMGG
GMGLLSSSSHRIVTETTRAAMPEVNIGLFPDATGSWFLQRFPAKTGLFMGLTGADANANDALLCNLADFKMSSQHFDAML
QSLCEADWREALGQPTLNSLSSKLHQITTKTLSEFSKQSVKSVEFAPSNIAKFMVPIQHLMSCGGLDKIDAILQSDSAIE
QFYPEFASSAWFQAAVGNYRYGCPVTKAITYEMYQRAHNLSLAEIMALETNVALHCVNYPDFSEGVRALLIDKDRKPQWS
RSLAECLDIEGQAYIQQHFQALS
>Mature_423_residues
MVIAVIFFIYKIIETGANIDMQFNDKSEAAQGIMAADSEEVVFERIQIKQGLIIGLVRLNREKSLNALSTHMCKLISAQL
TQWEKLDNLVAVVIRGAGERALCAGGDIRQLYQARQQWDKECMAPPEAIDFFASEYHLDTQMHEYHKPIIIWGSGIVMGG
GMGLLSSSSHRIVTETTRAAMPEVNIGLFPDATGSWFLQRFPAKTGLFMGLTGADANANDALLCNLADFKMSSQHFDAML
QSLCEADWREALGQPTLNSLSSKLHQITTKTLSEFSKQSVKSVEFAPSNIAKFMVPIQHLMSCGGLDKIDAILQSDSAIE
QFYPEFASSAWFQAAVGNYRYGCPVTKAITYEMYQRAHNLSLAEIMALETNVALHCVNYPDFSEGVRALLIDKDRKPQWS
RSLAECLDIEGQAYIQQHFQALS

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=386, Percent_Identity=32.1243523316062, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI37594469, Length=340, Percent_Identity=30.8823529411765, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI194097323, Length=171, Percent_Identity=30.9941520467836, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=370, Percent_Identity=29.1891891891892, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI25144157, Length=370, Percent_Identity=29.1891891891892, Blast_Score=161, Evalue=8e-40,
Organism=Saccharomyces cerevisiae, GI6320241, Length=360, Percent_Identity=29.1666666666667, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28571729, Length=345, Percent_Identity=32.1739130434783, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28571730, Length=345, Percent_Identity=32.1739130434783, Blast_Score=167, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 47043; Mature: 47043

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIAVIFFIYKIIETGANIDMQFNDKSEAAQGIMAADSEEVVFERIQIKQGLIIGLVRLN
CHHHHHHHHHHHHHCCCCCEEEECCHHHHHCCHHCCCCHHHHHHHHHHHCCCEEEHHHHC
REKSLNALSTHMCKLISAQLTQWEKLDNLVAVVIRGAGERALCAGGDIRQLYQARQQWDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHH
ECMAPPEAIDFFASEYHLDTQMHEYHKPIIIWGSGIVMGGGMGLLSSSSHRIVTETTRAA
HHCCCHHHHHHHHHHHHCCHHHHHHCCCEEEEECCEEEECCCCCCCCCCCEEEEHHHHHH
MPEVNIGLFPDATGSWFLQRFPAKTGLFMGLTGADANANDALLCNLADFKMSSQHFDAML
CCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEHHHCCCHHHHHHHH
QSLCEADWREALGQPTLNSLSSKLHQITTKTLSEFSKQSVKSVEFAPSNIAKFMVPIQHL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
MSCGGLDKIDAILQSDSAIEQFYPEFASSAWFQAAVGNYRYGCPVTKAITYEMYQRAHNL
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
SLAEIMALETNVALHCVNYPDFSEGVRALLIDKDRKPQWSRSLAECLDIEGQAYIQQHFQ
CHHHHHHHCCCEEEEEECCCCHHHHHHEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHH
ALS
HCC
>Mature Secondary Structure
MVIAVIFFIYKIIETGANIDMQFNDKSEAAQGIMAADSEEVVFERIQIKQGLIIGLVRLN
CHHHHHHHHHHHHHCCCCCEEEECCHHHHHCCHHCCCCHHHHHHHHHHHCCCEEEHHHHC
REKSLNALSTHMCKLISAQLTQWEKLDNLVAVVIRGAGERALCAGGDIRQLYQARQQWDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHH
ECMAPPEAIDFFASEYHLDTQMHEYHKPIIIWGSGIVMGGGMGLLSSSSHRIVTETTRAA
HHCCCHHHHHHHHHHHHCCHHHHHHCCCEEEEECCEEEECCCCCCCCCCCEEEEHHHHHH
MPEVNIGLFPDATGSWFLQRFPAKTGLFMGLTGADANANDALLCNLADFKMSSQHFDAML
CCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEHHHCCCHHHHHHHH
QSLCEADWREALGQPTLNSLSSKLHQITTKTLSEFSKQSVKSVEFAPSNIAKFMVPIQHL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
MSCGGLDKIDAILQSDSAIEQFYPEFASSAWFQAAVGNYRYGCPVTKAITYEMYQRAHNL
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
SLAEIMALETNVALHCVNYPDFSEGVRALLIDKDRKPQWSRSLAECLDIEGQAYIQQHFQ
CHHHHHHHCCCEEEEEECCCCHHHHHHEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHH
ALS
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA