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The map label for this gene is ilvE [H]

Identifier: 148652788

GI number: 148652788

Start: 1166995

End: 1167924

Strand: Direct

Name: ilvE [H]

Synonym: PsycPRwf_0981

Alternate gene names: 148652788

Gene position: 1166995-1167924 (Clockwise)

Preceding gene: 148652787

Following gene: 148652799

Centisome position: 39.17

GC content: 47.1

Gene sequence:

>930_bases
ATGAGTATGGCAACAACGGAAGGCAAGCTTTGGCTAAACGGTGAAATGGTCAATCAGCCTGATGCCAAAGTGCATGTGTT
AACGCACAGTTTGCATTATGGTATGGCAGTATTTGAAGGGGTGCGTGCTTATCAAACAGAAGATGGCCGTACTGCAATCT
TTAGATTAGAAGATCACACCGATCGCCTAATGGGCTCTGCCAAAATCTTTCAATTAAATGTCCCCTTTGATAAAGCCACT
TTGAATCAAGCCCAAAAAGAGGTCGTTAAACAAAATGGCTTTGAGTCGGCCTATATTCGTCCGCTTATCTGGGTGGGCGC
TGAAAAACTAGGACTCTCCTCACGAGATAATAGTATCAATGCCATGGTTGCCGCTTGGAAATGGGGCGCTTATTTGGGCG
AGGAGGGCATCCAAAAAGGAATCCGGGTGAAAACCTCATCCTATACCCACCATATGACCAACGTCACCATGTGTAAGGCC
AAAGCAGCGAGCAACTATCCAGTGTCTATTATGGCCAACCAAGAGGTGACTCGCAACGGCTATGACGAAGCCATCTTGAT
GGACTCTCAAGGCTATGTGTGCCAAGGTTCAGGCGAAAACTTATTTATGGTAAAAAATGGCGAGCTACATACGCCAGATT
TGGCAGGTGGGGCATTAGATGGGATTACCCGCCGTACGATGATTCAGTTCGCTGAGGATTTAGGCATTAAAGTGGTCGAA
CGCCGTATTACTCGCGATGAGTTTTATTTAGCCGATGAGGTGTTTATGACCGGTACTGCCGCTGAAGTGACGCCCATCCG
TGAATACGATGATCGCACCATTGGTAATGGCGGACGCGGTGACATCACACAGAAGCTGCAGAGCTTATATTTTGATGTGG
TACATGGCCGCAATGAGCAGTACATGGATTGGCTGAGCTTTGTTGATTAG

Upstream 100 bases:

>100_bases
GATATACTAAAATGATTGACCTCTCCTAAATATGCTGTTTATTATAAGGGGAGATCATGCAGGCTCGATTGACGATTATT
GGCGTAAAGGGAACAATATT

Downstream 100 bases:

>100_bases
TTAAGCGGTATAGCTGTTATGCTCTAAGCCCTTATTTTAGGGATGGCTTAATTATAAAAAAAATCCGGACATGATGTTCG
GATTTTTTTATGTGAAGTGT

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSMATTEGKLWLNGEMVNQPDAKVHVLTHSLHYGMAVFEGVRAYQTEDGRTAIFRLEDHTDRLMGSAKIFQLNVPFDKAT
LNQAQKEVVKQNGFESAYIRPLIWVGAEKLGLSSRDNSINAMVAAWKWGAYLGEEGIQKGIRVKTSSYTHHMTNVTMCKA
KAASNYPVSIMANQEVTRNGYDEAILMDSQGYVCQGSGENLFMVKNGELHTPDLAGGALDGITRRTMIQFAEDLGIKVVE
RRITRDEFYLADEVFMTGTAAEVTPIREYDDRTIGNGGRGDITQKLQSLYFDVVHGRNEQYMDWLSFVD

Sequences:

>Translated_309_residues
MSMATTEGKLWLNGEMVNQPDAKVHVLTHSLHYGMAVFEGVRAYQTEDGRTAIFRLEDHTDRLMGSAKIFQLNVPFDKAT
LNQAQKEVVKQNGFESAYIRPLIWVGAEKLGLSSRDNSINAMVAAWKWGAYLGEEGIQKGIRVKTSSYTHHMTNVTMCKA
KAASNYPVSIMANQEVTRNGYDEAILMDSQGYVCQGSGENLFMVKNGELHTPDLAGGALDGITRRTMIQFAEDLGIKVVE
RRITRDEFYLADEVFMTGTAAEVTPIREYDDRTIGNGGRGDITQKLQSLYFDVVHGRNEQYMDWLSFVD
>Mature_308_residues
SMATTEGKLWLNGEMVNQPDAKVHVLTHSLHYGMAVFEGVRAYQTEDGRTAIFRLEDHTDRLMGSAKIFQLNVPFDKATL
NQAQKEVVKQNGFESAYIRPLIWVGAEKLGLSSRDNSINAMVAAWKWGAYLGEEGIQKGIRVKTSSYTHHMTNVTMCKAK
AASNYPVSIMANQEVTRNGYDEAILMDSQGYVCQGSGENLFMVKNGELHTPDLAGGALDGITRRTMIQFAEDLGIKVVER
RITRDEFYLADEVFMTGTAAEVTPIREYDDRTIGNGGRGDITQKLQSLYFDVVHGRNEQYMDWLSFVD

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=299, Percent_Identity=26.7558528428094, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI258614015, Length=261, Percent_Identity=26.0536398467433, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI48994963, Length=301, Percent_Identity=44.1860465116279, Blast_Score=270, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI17565728, Length=304, Percent_Identity=25, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322608, Length=263, Percent_Identity=26.615969581749, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322002, Length=266, Percent_Identity=25.187969924812, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34615; Mature: 34483

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMATTEGKLWLNGEMVNQPDAKVHVLTHSLHYGMAVFEGVRAYQTEDGRTAIFRLEDHT
CCCCCCCCEEEECCEECCCCCCEEEEEEHHHHHHHHHHHHHHHEECCCCCEEEEEEECHH
DRLMGSAKIFQLNVPFDKATLNQAQKEVVKQNGFESAYIRPLIWVGAEKLGLSSRDNSIN
HHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHCEEEEECHHHHCCCCCCCCCE
AMVAAWKWGAYLGEEGIQKGIRVKTSSYTHHMTNVTMCKAKAASNYPVSIMANQEVTRNG
EEEEEEHHHHHHCHHHHHCCCEEEECCCEEECCEEEEEEECCCCCCCEEEEECCCHHCCC
YDEAILMDSQGYVCQGSGENLFMVKNGELHTPDLAGGALDGITRRTMIQFAEDLGIKVVE
CCCEEEECCCCCEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
RRITRDEFYLADEVFMTGTAAEVTPIREYDDRTIGNGGRGDITQKLQSLYFDVVHGRNEQ
HHHCCCCEEEECCEEEECCCCEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
YMDWLSFVD
HHHHHHHCC
>Mature Secondary Structure 
SMATTEGKLWLNGEMVNQPDAKVHVLTHSLHYGMAVFEGVRAYQTEDGRTAIFRLEDHT
CCCCCCCEEEECCEECCCCCCEEEEEEHHHHHHHHHHHHHHHEECCCCCEEEEEEECHH
DRLMGSAKIFQLNVPFDKATLNQAQKEVVKQNGFESAYIRPLIWVGAEKLGLSSRDNSIN
HHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHCEEEEECHHHHCCCCCCCCCE
AMVAAWKWGAYLGEEGIQKGIRVKTSSYTHHMTNVTMCKAKAASNYPVSIMANQEVTRNG
EEEEEEHHHHHHCHHHHHCCCEEEECCCEEECCEEEEEEECCCCCCCEEEEECCCHHCCC
YDEAILMDSQGYVCQGSGENLFMVKNGELHTPDLAGGALDGITRRTMIQFAEDLGIKVVE
CCCEEEECCCCCEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
RRITRDEFYLADEVFMTGTAAEVTPIREYDDRTIGNGGRGDITQKLQSLYFDVVHGRNEQ
HHHCCCCEEEECCEEEECCCCEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
YMDWLSFVD
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]