Click here to switch to the map view.

The map label for this gene is grxD [H]

Identifier: 148652770

GI number: 148652770

Start: 1149967

End: 1150302

Strand: Direct

Name: grxD [H]

Synonym: PsycPRwf_0963

Alternate gene names: 148652770

Gene position: 1149967-1150302 (Clockwise)

Preceding gene: 148652769

Following gene: 148652771

Centisome position: 38.6

GC content: 41.07

Gene sequence:

>336_bases
ATGACAGACCAAGCCCAAGACATCGAAACGTTAATTCGTAACCAGATTAAAGAAAACCCAGTGCTACTTTATATGAAAGG
TACGCCGCAGTTTCCGCAGTGTGGTTTTTCTGCTAAAGCCATTGAAGTATTAACTCAAATTGGTCGTCCATTTGCATTTG
TTAATATTTTAGAAAACCCTGAAATTCGTGCCACTTTGCCAAAAATTGCCAACTGGCCGACTTTCCCACAGCTTTGGATC
AATGGAGAGCTTATGGGTGGATCTGATATTATTCTAGAGATGTATCAATCAGGCGAGCTTAAGCCTTTAGTAGAAGAGCA
CAGCCCAGCTAACTAA

Upstream 100 bases:

>100_bases
TATTGACGCCTAGCTGACTCGGTACTAGCATTCACCAATTTGTTAAACTGTAGCTTTAAAACTGTAGTTGGCAACCTTGT
CTCACCATTAAGGAATTGAT

Downstream 100 bases:

>100_bases
TCGTTTAGCAGCGGTTGATTAAAATAAGTTAGTATCAAAGGCCCCGGAATGATTCTGGGGTTTTTTTTGGTCAAGAATTT
AAGAAGTAAAGCGATTTGAA

Product: glutaredoxin-like protein

Products: NA

Alternate protein names: Grx4; Monothiol glutaredoxin [H]

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MTDQAQDIETLIRNQIKENPVLLYMKGTPQFPQCGFSAKAIEVLTQIGRPFAFVNILENPEIRATLPKIANWPTFPQLWI
NGELMGGSDIILEMYQSGELKPLVEEHSPAN

Sequences:

>Translated_111_residues
MTDQAQDIETLIRNQIKENPVLLYMKGTPQFPQCGFSAKAIEVLTQIGRPFAFVNILENPEIRATLPKIANWPTFPQLWI
NGELMGGSDIILEMYQSGELKPLVEEHSPAN
>Mature_110_residues
TDQAQDIETLIRNQIKENPVLLYMKGTPQFPQCGFSAKAIEVLTQIGRPFAFVNILENPEIRATLPKIANWPTFPQLWIN
GELMGGSDIILEMYQSGELKPLVEEHSPAN

Specific function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters [H]

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI42516576, Length=86, Percent_Identity=45.3488372093023, Blast_Score=99, Evalue=5e-22,
Organism=Homo sapiens, GI95113651, Length=101, Percent_Identity=39.6039603960396, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787943, Length=97, Percent_Identity=62.8865979381443, Blast_Score=145, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17556042, Length=105, Percent_Identity=34.2857142857143, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988153, Length=86, Percent_Identity=37.2093023255814, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71988159, Length=80, Percent_Identity=37.5, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6325198, Length=105, Percent_Identity=45.7142857142857, Blast_Score=102, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321022, Length=78, Percent_Identity=47.4358974358974, Blast_Score=88, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320303, Length=74, Percent_Identity=50, Blast_Score=87, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24642023, Length=85, Percent_Identity=41.1764705882353, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI19921242, Length=101, Percent_Identity=34.6534653465347, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 12497; Mature: 12365

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQAQDIETLIRNQIKENPVLLYMKGTPQFPQCGFSAKAIEVLTQIGRPFAFVNILENP
CCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
EIRATLPKIANWPTFPQLWINGELMGGSDIILEMYQSGELKPLVEEHSPAN
CCEEECCCCCCCCCCCEEEECCEEECCHHHHHHHHHCCCCCCHHCCCCCCC
>Mature Secondary Structure 
TDQAQDIETLIRNQIKENPVLLYMKGTPQFPQCGFSAKAIEVLTQIGRPFAFVNILENP
CCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
EIRATLPKIANWPTFPQLWINGELMGGSDIILEMYQSGELKPLVEEHSPAN
CCEEECCCCCCCCCCCEEEECCEEECCHHHHHHHHHCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]