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The map label for this gene is hit [H]

Identifier: 148652759

GI number: 148652759

Start: 1138667

End: 1139098

Strand: Direct

Name: hit [H]

Synonym: PsycPRwf_0952

Alternate gene names: 148652759

Gene position: 1138667-1139098 (Clockwise)

Preceding gene: 148652758

Following gene: 148652760

Centisome position: 38.22

GC content: 44.44

Gene sequence:

>432_bases
ATGAGCATTAAGCATTACGAAGACGATAATATTTTTGCTAAGATTTTATCGGGTGATATCCCTTGTCACAAGGTATACGA
AGATGACAAGACCTTAGCTTTTATGGATATCATGCCGCAAGCTAAAGGTCATGTGTTGGTTATTCCTAAACAAAAAGCGG
TAGAGCTTTCGCAGCTTGAGCCTGAGTATGCCAGTGCGGTACTGATGACGGCCAAAAAGGTAATGGCAGCACAGCGTAAA
GTATTTGATCGTGAAGGCATTATTCAAATGCAGTTAAATGGCGCTGAGGCAGGTCAAACCGTCTTCCATTATCATGTGCA
TCTCATTCCCTCTAATATCCATGAGCTGGGTAAACATGCTGTGGTTCAAGCAGACATGGCAGAGCTTGCACAGCAGGCTG
AGCAGCTAGCAGCAGCGATTGAGCACGCTTAA

Upstream 100 bases:

>100_bases
TGCAACTTGTCAGCGGTTGGTGTTGAATAGTTGGATAAATACGACTGATGTTGAGGTAAACGTATGCCTCATATAAACCA
CAACAAATAAGGACATAACA

Downstream 100 bases:

>100_bases
CAGGCCGCTTTGGGCGCTGAGTGTCTAAACTTTAGGTTTTGAGTTAACGCTTGAGTTTTAGGTATTAGCCCTTACAATAA
CGGCAGGATAAAACGGGCTT

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MSIKHYEDDNIFAKILSGDIPCHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVELSQLEPEYASAVLMTAKKVMAAQRK
VFDREGIIQMQLNGAEAGQTVFHYHVHLIPSNIHELGKHAVVQADMAELAQQAEQLAAAIEHA

Sequences:

>Translated_143_residues
MSIKHYEDDNIFAKILSGDIPCHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVELSQLEPEYASAVLMTAKKVMAAQRK
VFDREGIIQMQLNGAEAGQTVFHYHVHLIPSNIHELGKHAVVQADMAELAQQAEQLAAAIEHA
>Mature_142_residues
SIKHYEDDNIFAKILSGDIPCHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVELSQLEPEYASAVLMTAKKVMAAQRKV
FDREGIIQMQLNGAEAGQTVFHYHVHLIPSNIHELGKHAVVQADMAELAQQAEQLAAAIEHA

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=103, Percent_Identity=38.8349514563107, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17506713, Length=106, Percent_Identity=35.8490566037736, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320078, Length=134, Percent_Identity=32.8358208955224, Blast_Score=68, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28574010, Length=105, Percent_Identity=38.0952380952381, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581222, Length=104, Percent_Identity=38.4615384615385, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15899; Mature: 15767

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKHYEDDNIFAKILSGDIPCHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVELSQLE
CCCCCCCCCHHHHHHHCCCCCCHHCCCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHCC
PEYASAVLMTAKKVMAAQRKVFDREGIIQMQLNGAEAGQTVFHYHVHLIPSNIHELGKHA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEECCHHHHHHHHHH
VVQADMAELAQQAEQLAAAIEHA
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIKHYEDDNIFAKILSGDIPCHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVELSQLE
CCCCCCCCHHHHHHHCCCCCCHHCCCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHCC
PEYASAVLMTAKKVMAAQRKVFDREGIIQMQLNGAEAGQTVFHYHVHLIPSNIHELGKHA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEECCHHHHHHHHHH
VVQADMAELAQQAEQLAAAIEHA
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]