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The map label for this gene is lysN [H]

Identifier: 148652709

GI number: 148652709

Start: 1073165

End: 1074364

Strand: Direct

Name: lysN [H]

Synonym: PsycPRwf_0902

Alternate gene names: 148652709

Gene position: 1073165-1074364 (Clockwise)

Preceding gene: 148652708

Following gene: 148652713

Centisome position: 36.02

GC content: 44.67

Gene sequence:

>1200_bases
ATGCAGTACGAGTTTTCAGAGGTGATTAACGGATTAAAACCCTCATTTATCCGCGAAATATTAAAGTTAACGGTTAAACC
AGAGATTATCTCCTTCGCCGGTGGTTTGCCAGATCCTACCTTGTTCCCACATCAGACCATCAAAGATGCCAGCAATGCCA
TGTTTGACCGCCAAGACAATGGTATCTTTCAGTATACCACCACTGAAGGTCACTTAGGCCTGCGCCAGTGGATTGCTAAG
CGTTTCTCAGATGCTCATGATGTACAAGTCGATGCAGATCAAGTGATGATTGTGTCCGGCTCACAGCAAGCACTAGATTT
ATTTGGCAAAATCTATATCAACCCACAAGATGGCGTGGTAATGGAGGCGCCGACCTATCTTGGGGCAATCCAAGCTTTTC
GTATGTACCAGCCTGAGTTTAAAGAAGTTGAACTGTTAGAGGATGGAATAGATACCGATCAGTTTCGCACTACCATGACG
CAGTCAGACAGTAAGTTTTTTTATGGTATTCCAAACTTCCAAAACCCAACGGGTTTAACTTATTCTGCTGATAAGCGTCA
GCAAGTGGCCGATATCTTACAAGATAGCGGCAAGCTGATGCTAGAAGATGACCCTTATGGCGCCTTATTGTTTGATGATC
CAAATACTCAAGGTATGACCACTCGTCCGATTTATGCACTGGCTCCTGAGCATGTAGTGTATATGGGCTCGTTCTCTAAA
GTATTTGTCCCCGGATTTAGATTGGGATGGGTAATTGCACCTAAGCCTGTGTTGGCTAAAATGGTCATCGCCAAGCAAGC
AGCTGACTTGCACACCAACTCATTTGTGCAGGAGCTGCTGTATCAGTATGTCACCACCAATGACTTAGATGCCCACATTG
ATGTCATTCGCCAGACCTATTCTGCTAAGAAAAGCTGCATGGTAGAGGCCATTCATACTTATCTAGGCGATGAGGTTGAG
ATGGCACCAGCCAATGGCGGTATGTTTATTTGGGTACGTGTACCGGGCGTGGCCGTGATGGATCTGCTTAAATATGCCAT
TGATAATAATGTCGCTTACGTGCCAGGTGAAGCCTTCTCATTGTCAGGTGAATATAAAGACTATATGCGTCTAAACTTCA
CAAGCTTAGATGATGAGCAGATTATTGAAGGAATTAAGCGCTTAAAAGCAGCACTGGATGCTTATCGTGCGGCTCAATAA

Upstream 100 bases:

>100_bases
ATGATAATAATTTACGTCAAATACTGGCCCAAAAAAGCACGCTAGCAATTATAAGCCCATCTACGCCAGTCAACCCAACT
TGTTATAAAAAGAGAGCGAT

Downstream 100 bases:

>100_bases
TATCGCAATAATTCATTGAGTCAGTCGTAATTTTGCAGGTGCAGACAGTAAAAAGTCACCGATTAATCGGTGACTTTTTT
AACGGCTATTTTTACTGCTT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MQYEFSEVINGLKPSFIREILKLTVKPEIISFAGGLPDPTLFPHQTIKDASNAMFDRQDNGIFQYTTTEGHLGLRQWIAK
RFSDAHDVQVDADQVMIVSGSQQALDLFGKIYINPQDGVVMEAPTYLGAIQAFRMYQPEFKEVELLEDGIDTDQFRTTMT
QSDSKFFYGIPNFQNPTGLTYSADKRQQVADILQDSGKLMLEDDPYGALLFDDPNTQGMTTRPIYALAPEHVVYMGSFSK
VFVPGFRLGWVIAPKPVLAKMVIAKQAADLHTNSFVQELLYQYVTTNDLDAHIDVIRQTYSAKKSCMVEAIHTYLGDEVE
MAPANGGMFIWVRVPGVAVMDLLKYAIDNNVAYVPGEAFSLSGEYKDYMRLNFTSLDDEQIIEGIKRLKAALDAYRAAQ

Sequences:

>Translated_399_residues
MQYEFSEVINGLKPSFIREILKLTVKPEIISFAGGLPDPTLFPHQTIKDASNAMFDRQDNGIFQYTTTEGHLGLRQWIAK
RFSDAHDVQVDADQVMIVSGSQQALDLFGKIYINPQDGVVMEAPTYLGAIQAFRMYQPEFKEVELLEDGIDTDQFRTTMT
QSDSKFFYGIPNFQNPTGLTYSADKRQQVADILQDSGKLMLEDDPYGALLFDDPNTQGMTTRPIYALAPEHVVYMGSFSK
VFVPGFRLGWVIAPKPVLAKMVIAKQAADLHTNSFVQELLYQYVTTNDLDAHIDVIRQTYSAKKSCMVEAIHTYLGDEVE
MAPANGGMFIWVRVPGVAVMDLLKYAIDNNVAYVPGEAFSLSGEYKDYMRLNFTSLDDEQIIEGIKRLKAALDAYRAAQ
>Mature_399_residues
MQYEFSEVINGLKPSFIREILKLTVKPEIISFAGGLPDPTLFPHQTIKDASNAMFDRQDNGIFQYTTTEGHLGLRQWIAK
RFSDAHDVQVDADQVMIVSGSQQALDLFGKIYINPQDGVVMEAPTYLGAIQAFRMYQPEFKEVELLEDGIDTDQFRTTMT
QSDSKFFYGIPNFQNPTGLTYSADKRQQVADILQDSGKLMLEDDPYGALLFDDPNTQGMTTRPIYALAPEHVVYMGSFSK
VFVPGFRLGWVIAPKPVLAKMVIAKQAADLHTNSFVQELLYQYVTTNDLDAHIDVIRQTYSAKKSCMVEAIHTYLGDEVE
MAPANGGMFIWVRVPGVAVMDLLKYAIDNNVAYVPGEAFSLSGEYKDYMRLNFTSLDDEQIIEGIKRLKAALDAYRAAQ

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=400, Percent_Identity=26.75, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI33469970, Length=400, Percent_Identity=26.75, Blast_Score=153, Evalue=3e-37,
Organism=Escherichia coli, GI1787710, Length=379, Percent_Identity=27.7044854881267, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1790797, Length=340, Percent_Identity=26.7647058823529, Blast_Score=119, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6321236, Length=486, Percent_Identity=23.6625514403292, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321000, Length=438, Percent_Identity=22.6027397260274, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321929, Length=286, Percent_Identity=23.7762237762238, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356535, Length=405, Percent_Identity=25.9259259259259, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 44822; Mature: 44822

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYEFSEVINGLKPSFIREILKLTVKPEIISFAGGLPDPTLFPHQTIKDASNAMFDRQDN
CCCCHHHHHCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCC
GIFQYTTTEGHLGLRQWIAKRFSDAHDVQVDADQVMIVSGSQQALDLFGKIYINPQDGVV
CEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHCEEEEEECCCCCEE
MEAPTYLGAIQAFRMYQPEFKEVELLEDGIDTDQFRTTMTQSDSKFFYGIPNFQNPTGLT
EECCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCE
YSADKRQQVADILQDSGKLMLEDDPYGALLFDDPNTQGMTTRPIYALAPEHVVYMGSFSK
ECCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCEECCEEEECCCEEEEECCCCC
VFVPGFRLGWVIAPKPVLAKMVIAKQAADLHTNSFVQELLYQYVTTNDLDAHIDVIRQTY
EECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
SAKKSCMVEAIHTYLGDEVEMAPANGGMFIWVRVPGVAVMDLLKYAIDNNVAYVPGEAFS
HHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCEEECCCCCEE
LSGEYKDYMRLNFTSLDDEQIIEGIKRLKAALDAYRAAQ
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQYEFSEVINGLKPSFIREILKLTVKPEIISFAGGLPDPTLFPHQTIKDASNAMFDRQDN
CCCCHHHHHCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCC
GIFQYTTTEGHLGLRQWIAKRFSDAHDVQVDADQVMIVSGSQQALDLFGKIYINPQDGVV
CEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHCEEEEEECCCCCEE
MEAPTYLGAIQAFRMYQPEFKEVELLEDGIDTDQFRTTMTQSDSKFFYGIPNFQNPTGLT
EECCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCE
YSADKRQQVADILQDSGKLMLEDDPYGALLFDDPNTQGMTTRPIYALAPEHVVYMGSFSK
ECCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCEECCEEEECCCEEEEECCCCC
VFVPGFRLGWVIAPKPVLAKMVIAKQAADLHTNSFVQELLYQYVTTNDLDAHIDVIRQTY
EECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
SAKKSCMVEAIHTYLGDEVEMAPANGGMFIWVRVPGVAVMDLLKYAIDNNVAYVPGEAFS
HHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCEEECCCCCEE
LSGEYKDYMRLNFTSLDDEQIIEGIKRLKAALDAYRAAQ
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA