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The map label for this gene is clpB [H]

Identifier: 148652685

GI number: 148652685

Start: 1038758

End: 1041346

Strand: Direct

Name: clpB [H]

Synonym: PsycPRwf_0876

Alternate gene names: 148652685

Gene position: 1038758-1041346 (Clockwise)

Preceding gene: 148652684

Following gene: 148652686

Centisome position: 34.87

GC content: 48.36

Gene sequence:

>2589_bases
ATGAGATTTGATAAATTCACTCAAAAGCTACAAGCAGCGCTCCAACAAGCTCAAAGTCTGGCCATCGGTCGAGACCACAC
CAGTATTGGACCGGTGCATATTATGGCCGCTTTATTAGAAGATGAGTCTAATATCTCGGTATGTCAGCAAGCCGGTGCCA
GTATTCCGGCACTAAAAAATGGCGTGGCCAAAGCCTTGGACAATCAGGCAGTGATTGCCAATCCAACTGGTGAAGTCAAC
TTAAGCCCAGATGCGGTGAAAGTGCTTAACTTAGCTGACCGTCAAGCCCAAAAAGCGGGCGATGATTATATTGCTACCGA
ATGGTTATTATTGGTGTTAGCGGAACAAGGCGATACCAAAAAACTGTTTAATACAGCCGGTGTTACTGCTGAGAAATTAA
AAGCGGTTATCGAACAATTGCGGGGAGAGCAGACTGTGGACAATCAAAATGCTGAAGATCAACGTGATGCGTTAAATAAA
TATACCATTAACCTAACTGAGCGTGCCGAGCTTGGTAAGCTTGATCCTGTGATTGGCCGAGATGAAGAGATTCGTCGTAC
CATTCAGGTGTTGTCACGCCGTACTAAGAATAATCCAGTACTTATCGGTGAGCCTGGTGTGGGTAAAACCGCCATTGTTG
AGGGTTTGGCTCAAAAAATCGTTAATGGCGATGTGCCAGAGGGTCTGCGCCGTAAAGAGGTGTTATCGTTAGACTTAGGT
GCCCTAATTGCTGGTGCAAAATATCGCGGTGAGTTTGAGGAGCGTCTAAAAAGCGTGCTCAATGATTTGGCCAAGCAAGA
AGGCAATGTCATCTTATTTATCGATGAGCTACACACGATGGTGGGCGCAGGTAAGTCGGATGGGGCGATGGATGCTGGCA
ACATGTTAAAGCCTGCTTTAGCACGTGGTGAGCTACACTGTGTGGGTGCAACAACGCTGGATGAATACCGTCAGTATATT
GAAAAAGATGCTGCCCTTGAGCGCCGTTTCCAAAAAGTATTGGTCGATGAGCCAACAGTCGAGGACACCATTGCCATCTT
GCGTGGTCTAAAAGAGCGCTATGAGCTGCACCACGGGGTAGATATCCAAGACAGCGCTATTATTGCTGCGGCGCGCATGA
GTCATCGTTATATCACCGACCGTAAGCTGCCTGATAAAGCCATTGACCTGGTGGATGAGGCCGCAAGCCGTCTGCGTATG
GAGATGGACAGCAAGCCTGAAGCCTTAGGTAAGCTTGACAGCCGCTTAATTCAGCTAAAAATGCAGCGTGAAGTCTTAAA
AAATGAAGAAGATGCTGGCGCTCAAGCAGAACGTAAGGTATTAGATGAGCAGATTGAAGAGCTTGAAAAAGAGTATGCTG
ATCTTAACGAGATTTGGCAGGCAGAAAAAGCGCTGGTCAAAGGCAGTCAGCAGCTAAAAGACGAGCTGGATAAAGCGCGT
ATTGCTTATGACAAAGCCAGCCGTGAGGGTGACTATGAGACCATGAGTAAGCTGCAGTATGAGACCATTCCGCAGTTAGA
AAAACGCATCACCGAATCTGACTTAGCTGAGCAAAAAGAGCAGACGGGTGAAGGCAATGGTATCAAGCTGCTGCGCAATA
AGGTAACCGATAACGAAATTGCTGAAGTGGTGGCGGCGGCTACCGGTATTCCGGTCAACAGAATGCTACAAGGTGAGCGT
GAGAAGATGCTGACGATGGAGGAGCGCTTGCATGAGCGAGTCGTCGGTCAAGATGAAGCGGTGCAGTCAGTGGCCAATGC
GGTGCGTCGTAGCCGTGCAGGTCTATCAGACCCCAACCGTCCATCAGGCTCTTTCTTATTCTTAGGCCCAACCGGTGTGG
GTAAAACTGAGCTGACCAAATCACTGGCCAACTTCTTGTTCGATAGTGAGGATGCGATGGTGCGTATCGACATGAGTGAA
TTCATGGAGAAGCACAGTGTCAGCCGCTTAGTCGGTGCGCCTCCTGGCTATGTGGGCTATGAAGAGGGCGGTGTATTGAC
CGAAGCGGTTCGCCGTAAGCCTTATAGCGTTATCTTGTTCGATGAGGTAGAAAAAGCGCATCCTGATGTGTTTAACATTC
TACTTCAGGTGCTTGATGATGGCCGTTTAACAGATTCACAGGGGCGAGTGGTGGATTTCAAAAACACAGTCATTATCATG
ACCAGTAACTTAGGCTCGCACAAAATCCAAGAGATGGCCGGTGATGATTATGAAGAAATCAAAGCATCAGTCATGGAGTC
TGTCGGTCAGCATTTCCGCCCTGAGTTTGTGAACCGTATCGATGAGATTGTGGTTTTCCATCCACTTGGTATGTCACAGA
TGGCCGGTATTGCCGACATCCAACTGGATCGTTTACGCAGCCGCTTAAAAGAGCGTGAGATGGACATCAAGCTGTCTGCT
GATGCGATGCATATGCTGGTGGCTGTGGGTTATGACCCTGTGTATGGCGCACGTCCGCTAAAACGTGCTATCCAGCAGCA
GATCGAAAACCCCTTGTCATTAAAGCTGTTGTCGGGTGAATTTGTCGCCGGTGATACCATCCAAGTGGATGTGGATGACG
AAGATAACCTGGTTTTCACCAAAGCCTAA

Upstream 100 bases:

>100_bases
AGTTAACAACAGGTGTATAGTATTTATGCCTTAAGTTAAAGATTGCTTTTAGACAATTGATATAAAAAATATAAAATACG
CCTATTACAAGGACAATCCT

Downstream 100 bases:

>100_bases
CTGTGCTTAGAGCAGACGGATAGGCAACTGGATTTATCACACAGCACACCCCTTATCTACGTAAGTAGGTAAGGGGTTTT
TTACTTTTAAGCCACAAGTC

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 862; Mature: 862

Protein sequence:

>862_residues
MRFDKFTQKLQAALQQAQSLAIGRDHTSIGPVHIMAALLEDESNISVCQQAGASIPALKNGVAKALDNQAVIANPTGEVN
LSPDAVKVLNLADRQAQKAGDDYIATEWLLLVLAEQGDTKKLFNTAGVTAEKLKAVIEQLRGEQTVDNQNAEDQRDALNK
YTINLTERAELGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVNGDVPEGLRRKEVLSLDLG
ALIAGAKYRGEFEERLKSVLNDLAKQEGNVILFIDELHTMVGAGKSDGAMDAGNMLKPALARGELHCVGATTLDEYRQYI
EKDAALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGVDIQDSAIIAAARMSHRYITDRKLPDKAIDLVDEAASRLRM
EMDSKPEALGKLDSRLIQLKMQREVLKNEEDAGAQAERKVLDEQIEELEKEYADLNEIWQAEKALVKGSQQLKDELDKAR
IAYDKASREGDYETMSKLQYETIPQLEKRITESDLAEQKEQTGEGNGIKLLRNKVTDNEIAEVVAAATGIPVNRMLQGER
EKMLTMEERLHERVVGQDEAVQSVANAVRRSRAGLSDPNRPSGSFLFLGPTGVGKTELTKSLANFLFDSEDAMVRIDMSE
FMEKHSVSRLVGAPPGYVGYEEGGVLTEAVRRKPYSVILFDEVEKAHPDVFNILLQVLDDGRLTDSQGRVVDFKNTVIIM
TSNLGSHKIQEMAGDDYEEIKASVMESVGQHFRPEFVNRIDEIVVFHPLGMSQMAGIADIQLDRLRSRLKEREMDIKLSA
DAMHMLVAVGYDPVYGARPLKRAIQQQIENPLSLKLLSGEFVAGDTIQVDVDDEDNLVFTKA

Sequences:

>Translated_862_residues
MRFDKFTQKLQAALQQAQSLAIGRDHTSIGPVHIMAALLEDESNISVCQQAGASIPALKNGVAKALDNQAVIANPTGEVN
LSPDAVKVLNLADRQAQKAGDDYIATEWLLLVLAEQGDTKKLFNTAGVTAEKLKAVIEQLRGEQTVDNQNAEDQRDALNK
YTINLTERAELGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVNGDVPEGLRRKEVLSLDLG
ALIAGAKYRGEFEERLKSVLNDLAKQEGNVILFIDELHTMVGAGKSDGAMDAGNMLKPALARGELHCVGATTLDEYRQYI
EKDAALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGVDIQDSAIIAAARMSHRYITDRKLPDKAIDLVDEAASRLRM
EMDSKPEALGKLDSRLIQLKMQREVLKNEEDAGAQAERKVLDEQIEELEKEYADLNEIWQAEKALVKGSQQLKDELDKAR
IAYDKASREGDYETMSKLQYETIPQLEKRITESDLAEQKEQTGEGNGIKLLRNKVTDNEIAEVVAAATGIPVNRMLQGER
EKMLTMEERLHERVVGQDEAVQSVANAVRRSRAGLSDPNRPSGSFLFLGPTGVGKTELTKSLANFLFDSEDAMVRIDMSE
FMEKHSVSRLVGAPPGYVGYEEGGVLTEAVRRKPYSVILFDEVEKAHPDVFNILLQVLDDGRLTDSQGRVVDFKNTVIIM
TSNLGSHKIQEMAGDDYEEIKASVMESVGQHFRPEFVNRIDEIVVFHPLGMSQMAGIADIQLDRLRSRLKEREMDIKLSA
DAMHMLVAVGYDPVYGARPLKRAIQQQIENPLSLKLLSGEFVAGDTIQVDVDDEDNLVFTKA
>Mature_862_residues
MRFDKFTQKLQAALQQAQSLAIGRDHTSIGPVHIMAALLEDESNISVCQQAGASIPALKNGVAKALDNQAVIANPTGEVN
LSPDAVKVLNLADRQAQKAGDDYIATEWLLLVLAEQGDTKKLFNTAGVTAEKLKAVIEQLRGEQTVDNQNAEDQRDALNK
YTINLTERAELGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVNGDVPEGLRRKEVLSLDLG
ALIAGAKYRGEFEERLKSVLNDLAKQEGNVILFIDELHTMVGAGKSDGAMDAGNMLKPALARGELHCVGATTLDEYRQYI
EKDAALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGVDIQDSAIIAAARMSHRYITDRKLPDKAIDLVDEAASRLRM
EMDSKPEALGKLDSRLIQLKMQREVLKNEEDAGAQAERKVLDEQIEELEKEYADLNEIWQAEKALVKGSQQLKDELDKAR
IAYDKASREGDYETMSKLQYETIPQLEKRITESDLAEQKEQTGEGNGIKLLRNKVTDNEIAEVVAAATGIPVNRMLQGER
EKMLTMEERLHERVVGQDEAVQSVANAVRRSRAGLSDPNRPSGSFLFLGPTGVGKTELTKSLANFLFDSEDAMVRIDMSE
FMEKHSVSRLVGAPPGYVGYEEGGVLTEAVRRKPYSVILFDEVEKAHPDVFNILLQVLDDGRLTDSQGRVVDFKNTVIIM
TSNLGSHKIQEMAGDDYEEIKASVMESVGQHFRPEFVNRIDEIVVFHPLGMSQMAGIADIQLDRLRSRLKEREMDIKLSA
DAMHMLVAVGYDPVYGARPLKRAIQQQIENPLSLKLLSGEFVAGDTIQVDVDDEDNLVFTKA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=323, Percent_Identity=38.6996904024768, Blast_Score=221, Evalue=3e-57,
Organism=Escherichia coli, GI1788943, Length=862, Percent_Identity=66.1252900232019, Blast_Score=1137, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=319, Percent_Identity=43.2601880877743, Blast_Score=275, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6320464, Length=715, Percent_Identity=53.5664335664336, Blast_Score=763, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=875, Percent_Identity=42.6285714285714, Blast_Score=671, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95658; Mature: 95658

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDKFTQKLQAALQQAQSLAIGRDHTSIGPVHIMAALLEDESNISVCQQAGASIPALKN
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCHHHH
GVAKALDNQAVIANPTGEVNLSPDAVKVLNLADRQAQKAGDDYIATEWLLLVLAEQGDTK
HHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHH
KLFNTAGVTAEKLKAVIEQLRGEQTVDNQNAEDQRDALNKYTINLTERAELGKLDPVIGR
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEEEECHHHCCCCCCCCCC
DEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVNGDVPEGLRRKEVLSLDLG
CHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ALIAGAKYRGEFEERLKSVLNDLAKQEGNVILFIDELHTMVGAGKSDGAMDAGNMLKPAL
HHHHCCHHCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHH
ARGELHCVGATTLDEYRQYIEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGV
HCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
DIQDSAIIAAARMSHRYITDRKLPDKAIDLVDEAASRLRMEMDSKPEALGKLDSRLIQLK
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MQREVLKNEEDAGAQAERKVLDEQIEELEKEYADLNEIWQAEKALVKGSQQLKDELDKAR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
IAYDKASREGDYETMSKLQYETIPQLEKRITESDLAEQKEQTGEGNGIKLLRNKVTDNEI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHH
AEVVAAATGIPVNRMLQGEREKMLTMEERLHERVVGQDEAVQSVANAVRRSRAGLSDPNR
HHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
PSGSFLFLGPTGVGKTELTKSLANFLFDSEDAMVRIDMSEFMEKHSVSRLVGAPPGYVGY
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCC
EEGGVLTEAVRRKPYSVILFDEVEKAHPDVFNILLQVLDDGRLTDSQGRVVDFKNTVIIM
CCCCHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEE
TSNLGSHKIQEMAGDDYEEIKASVMESVGQHFRPEFVNRIDEIVVFHPLGMSQMAGIADI
ECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCCHHHHCCHHHH
QLDRLRSRLKEREMDIKLSADAMHMLVAVGYDPVYGARPLKRAIQQQIENPLSLKLLSGE
HHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCC
FVAGDTIQVDVDDEDNLVFTKA
EEECCEEEEEECCCCCEEEECC
>Mature Secondary Structure
MRFDKFTQKLQAALQQAQSLAIGRDHTSIGPVHIMAALLEDESNISVCQQAGASIPALKN
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCHHHH
GVAKALDNQAVIANPTGEVNLSPDAVKVLNLADRQAQKAGDDYIATEWLLLVLAEQGDTK
HHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHH
KLFNTAGVTAEKLKAVIEQLRGEQTVDNQNAEDQRDALNKYTINLTERAELGKLDPVIGR
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEEEECHHHCCCCCCCCCC
DEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVNGDVPEGLRRKEVLSLDLG
CHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ALIAGAKYRGEFEERLKSVLNDLAKQEGNVILFIDELHTMVGAGKSDGAMDAGNMLKPAL
HHHHCCHHCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHH
ARGELHCVGATTLDEYRQYIEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGV
HCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
DIQDSAIIAAARMSHRYITDRKLPDKAIDLVDEAASRLRMEMDSKPEALGKLDSRLIQLK
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MQREVLKNEEDAGAQAERKVLDEQIEELEKEYADLNEIWQAEKALVKGSQQLKDELDKAR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
IAYDKASREGDYETMSKLQYETIPQLEKRITESDLAEQKEQTGEGNGIKLLRNKVTDNEI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHH
AEVVAAATGIPVNRMLQGEREKMLTMEERLHERVVGQDEAVQSVANAVRRSRAGLSDPNR
HHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
PSGSFLFLGPTGVGKTELTKSLANFLFDSEDAMVRIDMSEFMEKHSVSRLVGAPPGYVGY
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCC
EEGGVLTEAVRRKPYSVILFDEVEKAHPDVFNILLQVLDDGRLTDSQGRVVDFKNTVIIM
CCCCHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEE
TSNLGSHKIQEMAGDDYEEIKASVMESVGQHFRPEFVNRIDEIVVFHPLGMSQMAGIADI
ECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCCHHHHCCHHHH
QLDRLRSRLKEREMDIKLSADAMHMLVAVGYDPVYGARPLKRAIQQQIENPLSLKLLSGE
HHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCC
FVAGDTIQVDVDDEDNLVFTKA
EEECCEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]