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The map label for this gene is kdsC [H]

Identifier: 148652632

GI number: 148652632

Start: 978038

End: 978565

Strand: Direct

Name: kdsC [H]

Synonym: PsycPRwf_0823

Alternate gene names: 148652632

Gene position: 978038-978565 (Clockwise)

Preceding gene: 148652631

Following gene: 148652633

Centisome position: 32.83

GC content: 43.56

Gene sequence:

>528_bases
ATGCAAGACTTAATCCAAGCTGCAGGCAAAGTAAAATTGTTGGTGCTCGATGTAGATGGCATCTTATCTAATGGCTATAT
TATTTATGATGGCGAAGAGATAGAGACCAAGTGTTTTAATGTGAAAGATGGCATGGGCATCAAAGCAGTAAAATGGGCCG
GCGTTAAAACGGCCATTATCACAGGTCGATCAAGTCCTATGGTCAATAAAAGGGCCAAAGAGATGGGTATTGATTATGTA
ATCCAAGGCCGTGATGATAAGCTTGAAGCGCTTAATCAGCTCCTATTAGATTTGCCAATAAGCTTAGAGCAGTGTGCTTA
TATGGGTGATGATCTGCCAGATATTAAGGCCCTGCAGTCGGTGGGTTTCTCTGCTACAGTAGCTAATGCCCATGCTGAGG
TATTAAGCCGAGTGATGATGGTCACCACGCGCGCAGGTGGAGAGGGTGCCGTACGTGAGGTTTGTGATTTGATTTTAAAA
GGTCATGGCAAGTACGAGCAATATATTAGCCAGTATGTGCTTGATTAA

Upstream 100 bases:

>100_bases
ATAAAAGGCTGTGCGCTTTTTACAGCTGTTGAGCCACTAAATACTGTCTTATTTTTTAATACATTTCAATTCGCGACGAC
ACATAGGGTAAGTAGATATT

Downstream 100 bases:

>100_bases
TCAGCACTTAACACCATTTATTTTTTGTTATGGTCATAAAGAGGTGTAATGAATACCCGATTTTTATTTATCCTATCCTT
GCTTGTGGCAGTGTTTGCGG

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MQDLIQAAGKVKLLVLDVDGILSNGYIIYDGEEIETKCFNVKDGMGIKAVKWAGVKTAIITGRSSPMVNKRAKEMGIDYV
IQGRDDKLEALNQLLLDLPISLEQCAYMGDDLPDIKALQSVGFSATVANAHAEVLSRVMMVTTRAGGEGAVREVCDLILK
GHGKYEQYISQYVLD

Sequences:

>Translated_175_residues
MQDLIQAAGKVKLLVLDVDGILSNGYIIYDGEEIETKCFNVKDGMGIKAVKWAGVKTAIITGRSSPMVNKRAKEMGIDYV
IQGRDDKLEALNQLLLDLPISLEQCAYMGDDLPDIKALQSVGFSATVANAHAEVLSRVMMVTTRAGGEGAVREVCDLILK
GHGKYEQYISQYVLD
>Mature_175_residues
MQDLIQAAGKVKLLVLDVDGILSNGYIIYDGEEIETKCFNVKDGMGIKAVKWAGVKTAIITGRSSPMVNKRAKEMGIDYV
IQGRDDKLEALNQLLLDLPISLEQCAYMGDDLPDIKALQSVGFSATVANAHAEVLSRVMMVTTRAGGEGAVREVCDLILK
GHGKYEQYISQYVLD

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=150, Percent_Identity=28.6666666666667, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI2367202, Length=171, Percent_Identity=44.4444444444444, Blast_Score=141, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19082; Mature: 19082

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLIQAAGKVKLLVLDVDGILSNGYIIYDGEEIETKCFNVKDGMGIKAVKWAGVKTAII
CCHHHHHCCCEEEEEEECCCHHHCCEEEECCCCHHHEEECCCCCCCEEEEEECCCEEEEE
TGRSSPMVNKRAKEMGIDYVIQGRDDKLEALNQLLLDLPISLEQCAYMGDDLPDIKALQS
ECCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHH
VGFSATVANAHAEVLSRVMMVTTRAGGEGAVREVCDLILKGHGKYEQYISQYVLD
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQDLIQAAGKVKLLVLDVDGILSNGYIIYDGEEIETKCFNVKDGMGIKAVKWAGVKTAII
CCHHHHHCCCEEEEEEECCCHHHCCEEEECCCCHHHEEECCCCCCCEEEEEECCCEEEEE
TGRSSPMVNKRAKEMGIDYVIQGRDDKLEALNQLLLDLPISLEQCAYMGDDLPDIKALQS
ECCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHH
VGFSATVANAHAEVLSRVMMVTTRAGGEGAVREVCDLILKGHGKYEQYISQYVLD
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]