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The map label for this gene is mreB [H]

Identifier: 148652232

GI number: 148652232

Start: 516770

End: 517798

Strand: Direct

Name: mreB [H]

Synonym: PsycPRwf_0420

Alternate gene names: 148652232

Gene position: 516770-517798 (Clockwise)

Preceding gene: 148652228

Following gene: 148652233

Centisome position: 17.35

GC content: 48.49

Gene sequence:

>1029_bases
ATGAACCCGTTTGGATTTCTATCTAACAATATCGCCATTGACCTTGGTACTGCCAACACATTGATTTATGCGCCTGGAAA
GGGTGTGGTTCTCGACGAGCCCACGGTAGTGGCTCTGCGTAGTAATCGCACTCAAAATCCAACGGTAGCTGCTGTCGGCA
TCGATGCAAAGCAAATGCTGGGTCGTACACCGGACAATATCACCGCCATTCGCCCGTTAAAAGATGGGGTTATTGCAGAT
TTTGAGGTCACTCAAAAAATGCTAAAACACTTCATCAATAAAGTAAAAGCGCGTCGCTTTTTGGCTCAGCCAAACGTTGT
GGTTTGTGTGCCTTGCAAATCGACCTTAGTTGAGCGTCGTGCCATTCGTGAAGCGGTATCTTCTGCTGGCGCCAACAAAG
TCTTTTTATTAGAAGAGCCGATGGCAGCTGCCATTGGTGCCGACCTGCCAGTGCATGAAGCCAGTGGCTCTATGGTTGTG
GATATCGGTGGTGGTACCACTGAGATTGCCGTCATCTCATTATCAGGCTGCGTCTATGCCGACTCTATCCGTATCGGCGG
CGACATCTTTGATGAGGCGATTATCACGCACGTTCGCCGCAATCATGGCTGCGTAATTGGTGAAACCACAGCTGAGCGTA
TCAAGCAAAGCGTAGGCTCGGCCATTGATGAAGATGCCAAGCTTGAAGTTGAAGTGCGCGGCCGTAGTATGGCTGAAGGG
GTGCCTAAGACCTTAACGGTGACCTCTGAAGAAGTTCAAAAGGCATTAAGCGACTCATTAACCGGTATTGTTAGTGCGGT
AAAAACTGCCCTAGAACAGACGCCACCTGAATTGTCATCAGACATCGCTGAGCGTGGTATCGTGTTAACCGGTGGCGGCG
CTTTGTTGCGTAACTTTGATAAATTATTGTCAAAAGAAACCGGTCTACCGGTTACCGTTGCAGAAGACCCCTTAACGTGT
GTGAGCCGTGGCGGCGGTGCTGCATTAGCATTTATCAATAATAAAAGTCTTAATATGATTTTTGTGTAG

Upstream 100 bases:

>100_bases
TTAGTAAATCAAACTCACTTATTTGAGAGCCAATCTTAGCGAATTAACGGCTGATGATGACGGCTTCTCTTTAACTCGCA
ATACGCTGGAAACACGATAC

Downstream 100 bases:

>100_bases
CCGATGAGTTTATAAATTTAATATGCCAACAAGCATCTTTGCTCAGTACAGTCTATCGTTACGAAAAACAGCGGCCGTGT
TATTGGTCGCTATGATTTTG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNPFGFLSNNIAIDLGTANTLIYAPGKGVVLDEPTVVALRSNRTQNPTVAAVGIDAKQMLGRTPDNITAIRPLKDGVIAD
FEVTQKMLKHFINKVKARRFLAQPNVVVCVPCKSTLVERRAIREAVSSAGANKVFLLEEPMAAAIGADLPVHEASGSMVV
DIGGGTTEIAVISLSGCVYADSIRIGGDIFDEAIITHVRRNHGCVIGETTAERIKQSVGSAIDEDAKLEVEVRGRSMAEG
VPKTLTVTSEEVQKALSDSLTGIVSAVKTALEQTPPELSSDIAERGIVLTGGGALLRNFDKLLSKETGLPVTVAEDPLTC
VSRGGGAALAFINNKSLNMIFV

Sequences:

>Translated_342_residues
MNPFGFLSNNIAIDLGTANTLIYAPGKGVVLDEPTVVALRSNRTQNPTVAAVGIDAKQMLGRTPDNITAIRPLKDGVIAD
FEVTQKMLKHFINKVKARRFLAQPNVVVCVPCKSTLVERRAIREAVSSAGANKVFLLEEPMAAAIGADLPVHEASGSMVV
DIGGGTTEIAVISLSGCVYADSIRIGGDIFDEAIITHVRRNHGCVIGETTAERIKQSVGSAIDEDAKLEVEVRGRSMAEG
VPKTLTVTSEEVQKALSDSLTGIVSAVKTALEQTPPELSSDIAERGIVLTGGGALLRNFDKLLSKETGLPVTVAEDPLTC
VSRGGGAALAFINNKSLNMIFV
>Mature_342_residues
MNPFGFLSNNIAIDLGTANTLIYAPGKGVVLDEPTVVALRSNRTQNPTVAAVGIDAKQMLGRTPDNITAIRPLKDGVIAD
FEVTQKMLKHFINKVKARRFLAQPNVVVCVPCKSTLVERRAIREAVSSAGANKVFLLEEPMAAAIGADLPVHEASGSMVV
DIGGGTTEIAVISLSGCVYADSIRIGGDIFDEAIITHVRRNHGCVIGETTAERIKQSVGSAIDEDAKLEVEVRGRSMAEG
VPKTLTVTSEEVQKALSDSLTGIVSAVKTALEQTPPELSSDIAERGIVLTGGGALLRNFDKLLSKETGLPVTVAEDPLTC
VSRGGGAALAFINNKSLNMIFV

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=234, Percent_Identity=28.6324786324786, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI24234686, Length=257, Percent_Identity=26.8482490272374, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI5729877, Length=257, Percent_Identity=26.8482490272374, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI124256496, Length=234, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI16507237, Length=313, Percent_Identity=24.6006389776358, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI13676857, Length=257, Percent_Identity=26.0700389105058, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI167466173, Length=268, Percent_Identity=25.7462686567164, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI194248072, Length=268, Percent_Identity=25.7462686567164, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082236, Length=331, Percent_Identity=67.97583081571, Blast_Score=452, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17534015, Length=356, Percent_Identity=25.8426966292135, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17534013, Length=356, Percent_Identity=25.8426966292135, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17541098, Length=250, Percent_Identity=24.4, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507981, Length=362, Percent_Identity=24.585635359116, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24647034, Length=301, Percent_Identity=25.9136212624585, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24647038, Length=301, Percent_Identity=25.9136212624585, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24647036, Length=301, Percent_Identity=25.9136212624585, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17737967, Length=301, Percent_Identity=25.9136212624585, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28571721, Length=301, Percent_Identity=25.9136212624585, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28571719, Length=301, Percent_Identity=25.9136212624585, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17647515, Length=221, Percent_Identity=26.6968325791855, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36057; Mature: 36057

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFGFLSNNIAIDLGTANTLIYAPGKGVVLDEPTVVALRSNRTQNPTVAAVGIDAKQML
CCCCCEECCCEEEEECCCCEEEECCCCCEEECCCEEEEEECCCCCCCEEEEEECCHHHHH
GRTPDNITAIRPLKDGVIADFEVTQKMLKHFINKVKARRFLAQPNVVVCVPCKSTLVERR
CCCCCCCEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
AIREAVSSAGANKVFLLEEPMAAAIGADLPVHEASGSMVVDIGGGTTEIAVISLSGCVYA
HHHHHHHHCCCCEEEEECCCHHHHHCCCCCEEECCCCEEEEECCCCEEEEEEEECCEEEE
DSIRIGGDIFDEAIITHVRRNHGCVIGETTAERIKQSVGSAIDEDAKLEVEVRGRSMAEG
CCEEECCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCHHHCC
VPKTLTVTSEEVQKALSDSLTGIVSAVKTALEQTPPELSSDIAERGIVLTGGGALLRNFD
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECCHHHHHHHH
KLLSKETGLPVTVAEDPLTCVSRGGGAALAFINNKSLNMIFV
HHHHHCCCCEEEECCCCHHHHCCCCCEEEEEEECCCEEEEEC
>Mature Secondary Structure
MNPFGFLSNNIAIDLGTANTLIYAPGKGVVLDEPTVVALRSNRTQNPTVAAVGIDAKQML
CCCCCEECCCEEEEECCCCEEEECCCCCEEECCCEEEEEECCCCCCCEEEEEECCHHHHH
GRTPDNITAIRPLKDGVIADFEVTQKMLKHFINKVKARRFLAQPNVVVCVPCKSTLVERR
CCCCCCCEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
AIREAVSSAGANKVFLLEEPMAAAIGADLPVHEASGSMVVDIGGGTTEIAVISLSGCVYA
HHHHHHHHCCCCEEEEECCCHHHHHCCCCCEEECCCCEEEEECCCCEEEEEEEECCEEEE
DSIRIGGDIFDEAIITHVRRNHGCVIGETTAERIKQSVGSAIDEDAKLEVEVRGRSMAEG
CCEEECCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCHHHCC
VPKTLTVTSEEVQKALSDSLTGIVSAVKTALEQTPPELSSDIAERGIVLTGGGALLRNFD
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECCHHHHHHHH
KLLSKETGLPVTVAEDPLTCVSRGGGAALAFINNKSLNMIFV
HHHHHCCCCEEEECCCCHHHHCCCCCEEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]