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The map label for this gene is rfk

Identifier: 148643317

GI number: 148643317

Start: 1262146

End: 1262520

Strand: Reverse

Name: rfk

Synonym: Msm_1257

Alternate gene names: 148643317

Gene position: 1262520-1262146 (Counterclockwise)

Preceding gene: 148643319

Following gene: 148643316

Centisome position: 68.13

GC content: 30.4

Gene sequence:

>375_bases
ATGAAAATTGATGGAACAGTTACAACTGGTTTAGGCAAAGCCGCTTATTTTTTATCACAGGATTTTTATGTTAATAATTT
TAAAAAAAATTGTGGATTTCGCCCGTATCCAGGAACTTTAAATGTTATAGTTCCAGAAGAGTACCTTCCTCAAATCAACA
AAGTGAAAAATGAATGTAAAAATATTATAAAACCTGATGAAGGTTTTGGTGCTGTTAAATATATAAAAGCAAGATTAAAT
GATGAAGTTACTGGGGCTATTGTATTTCCGGCTAAAACTACACATGAAGAAAATTATTTGGAGTTTATAGCTAAAGATAA
ACTTAGGGATAAGCTAAATCTTGAAGACGGAGATACGGTAAGTGTTGAATTTTAA

Upstream 100 bases:

>100_bases
TAAAATTTATTCTGAAATAGCTACTTTTAATTAAATTAATTATATAGTCAATAATTTTTAATCAAATTATAATTCATTGT
ATATATTTGGAGGTTTTTTA

Downstream 100 bases:

>100_bases
AAATGTTTTAAGAAACTTTTTATAATATAATTTATATATTATTTCATTGTACAATTCTCAGGGCGGAGTGAAATTCTCCA
CCGGTGGTGTTTCTGAAATA

Product: riboflavin kinase

Products: NA

Alternate protein names: RFK; CTP-dependent riboflavin kinase; CTP:riboflavin 5'-phosphotransferase; Flavokinase

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MKIDGTVTTGLGKAAYFLSQDFYVNNFKKNCGFRPYPGTLNVIVPEEYLPQINKVKNECKNIIKPDEGFGAVKYIKARLN
DEVTGAIVFPAKTTHEENYLEFIAKDKLRDKLNLEDGDTVSVEF

Sequences:

>Translated_124_residues
MKIDGTVTTGLGKAAYFLSQDFYVNNFKKNCGFRPYPGTLNVIVPEEYLPQINKVKNECKNIIKPDEGFGAVKYIKARLN
DEVTGAIVFPAKTTHEENYLEFIAKDKLRDKLNLEDGDTVSVEF
>Mature_124_residues
MKIDGTVTTGLGKAAYFLSQDFYVNNFKKNCGFRPYPGTLNVIVPEEYLPQINKVKNECKNIIKPDEGFGAVKYIKARLN
DEVTGAIVFPAKTTHEENYLEFIAKDKLRDKLNLEDGDTVSVEF

Specific function: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN)

COG id: COG1339

COG function: function code KH; Transcriptional regulator of a riboflavin/FAD biosynthetic operon

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal riboflavin kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIFK_METS3 (A5UMN4)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273830.1
- ProteinModelPortal:   A5UMN4
- SMR:   A5UMN4
- STRING:   A5UMN4
- GeneID:   5215775
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_1257
- eggNOG:   arNOG10832
- HOGENOM:   HBG553349
- OMA:   KTTHEEN
- ProtClustDB:   PRK14132
- HAMAP:   MF_01285
- InterPro:   IPR015865
- InterPro:   IPR002834
- Gene3D:   G3DSA:2.40.30.30

Pfam domain/function: PF01982 CTP-dep_RFKase

EC number: =2.7.1.161

Molecular weight: Translated: 14013; Mature: 14013

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: BINDING 93-93 BINDING 101-101

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDGTVTTGLGKAAYFLSQDFYVNNFKKNCGFRPYPGTLNVIVPEEYLPQINKVKNECK
CCCCCEEECCCCHHHHHHCCCCEECCHHHCCCCCCCCCEEEEEECHHHCCHHHHHHHHHH
NIIKPDEGFGAVKYIKARLNDEVTGAIVFPAKTTHEENYLEFIAKDKLRDKLNLEDGDTV
HHCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEE
SVEF
EEEC
>Mature Secondary Structure
MKIDGTVTTGLGKAAYFLSQDFYVNNFKKNCGFRPYPGTLNVIVPEEYLPQINKVKNECK
CCCCCEEECCCCHHHHHHCCCCEECCHHHCCCCCCCCCEEEEEECHHHCCHHHHHHHHHH
NIIKPDEGFGAVKYIKARLNDEVTGAIVFPAKTTHEENYLEFIAKDKLRDKLNLEDGDTV
HHCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEE
SVEF
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA