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The map label for this gene is aspC [H]

Identifier: 148643296

GI number: 148643296

Start: 1238418

End: 1239737

Strand: Reverse

Name: aspC [H]

Synonym: Msm_1236

Alternate gene names: 148643296

Gene position: 1239737-1238418 (Counterclockwise)

Preceding gene: 148643300

Following gene: 148643295

Centisome position: 66.9

GC content: 34.39

Gene sequence:

>1320_bases
ATGCAAGGTTTATTAAATGAATGGAGAAGAACAAATTATACTAAAAATGTCACTCCTGATTTAACTGGACAAGATGTCAT
CGTCATGGGTTGGGTACATGAAATCCGTGATTTAGGTGGAATCATCTTTGTTATTATTAGAGATAGAGAAGGTAAGGTAC
AAATTACCGCACCAAGTAAAAAAGTAGATGCAGAAATACTTGAAGATATTAGGAAACTTAGAAAAGAATCCGTTGTAGCT
ATTAAAGGTACAGTTCAGGAAGCTAACCAAGCACCTACTGGTGTTGAAATTATTCCTAAAGAAATTAATCTTTTAAACTT
AGCTAATCAGCCACTTCCTATGGATCCTACTGATAAAGTTAAAGCTGAAATTGATACCAGGTTAGACTCCAGATTCATTG
ATTTAAGAAGGGATAATGTCAGTGCTATTTTTAAAATTAAAAATAGAATGTTCCATACTATAAGGGATTTCTTCTATGAA
AATGGATTTATGGAAATTAACACTCCAAAACTTGTAGCTTCTGCTACTGAAGGAGGAACTGAACTTTTCCCAATTACATA
TTTCGAAAAAGAAGCATTCTTAGGTCAGTCTCCACAATTATACAAACAGATGATGATGTCTAGTGGAATGGATAAAGTAT
TTGAAATCGGTCAAATTTTCAGAGCTGAAGAACATGATACTTTAAGACACTTAAATGAAGCTGTTTCTATTGATGCGGAA
GCTTCTTTTATGGACGATATTGATGTAATGAAAATACTTAATAATATGCTTGAACAAGTTATCATTGACATTAATGAAGA
CTGTAAAGAAGAATTAAATATATTAGAACATGAAATGCCTGTTCCTGACGGTCCTTTCCCTGTTGTAACTTATGATGAAG
CAGTTGATATTGTAAACTCCAGAGATGTTGAAATGAGCTGGGGTGAAGATTTATCCCGTGCAGGTGAAAAAGCATTAGGT
GATGTAATGGGAGGATTCTACTTCTTAACTGAATGGCCTTCTGAAATTAAACCATTTTACGTAATGCCTAATTCCAAAGA
CCCTACTAAAGCACATGCATTTGATTTGATGTATAATAACTTGGAATTATCCTCTGGTGCTACTCGTGTACACCAATATG
ATGTTTTAGTAAAACAAATTGAAGAAAAAGGATTAAATGTAGCTTCATTTGGCAGCTACTTAAAAGCTTTCGAATATGGT
ATGCCTCCTCATGCTGGTTGGGGTGTAGGTGCTGACAGATTAGCTATGGTACTTACAGGTGTTGAAAATATTCGTGAAAC
AGTTCTCTTCCCAAGAGACAGACACAGATTAACTCCTTAA

Upstream 100 bases:

>100_bases
TTAATCAAATACTTTATTAAATATAAAAATTAAATTTCTTAATATAATGAAAAATTAATTTTATTATAATTATTTTTTTA
AAAAACCTAGAGGTGAACCA

Downstream 100 bases:

>100_bases
ATTTTGATTAATATGGAAGAATTTGATATAGCTATAATTGGCGGAGGTCCTGCAGGAATAATGGCTGCAATTGCTGCTTC
TGCAGATTTGAATGTTGTAT

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MQGLLNEWRRTNYTKNVTPDLTGQDVIVMGWVHEIRDLGGIIFVIIRDREGKVQITAPSKKVDAEILEDIRKLRKESVVA
IKGTVQEANQAPTGVEIIPKEINLLNLANQPLPMDPTDKVKAEIDTRLDSRFIDLRRDNVSAIFKIKNRMFHTIRDFFYE
NGFMEINTPKLVASATEGGTELFPITYFEKEAFLGQSPQLYKQMMMSSGMDKVFEIGQIFRAEEHDTLRHLNEAVSIDAE
ASFMDDIDVMKILNNMLEQVIIDINEDCKEELNILEHEMPVPDGPFPVVTYDEAVDIVNSRDVEMSWGEDLSRAGEKALG
DVMGGFYFLTEWPSEIKPFYVMPNSKDPTKAHAFDLMYNNLELSSGATRVHQYDVLVKQIEEKGLNVASFGSYLKAFEYG
MPPHAGWGVGADRLAMVLTGVENIRETVLFPRDRHRLTP

Sequences:

>Translated_439_residues
MQGLLNEWRRTNYTKNVTPDLTGQDVIVMGWVHEIRDLGGIIFVIIRDREGKVQITAPSKKVDAEILEDIRKLRKESVVA
IKGTVQEANQAPTGVEIIPKEINLLNLANQPLPMDPTDKVKAEIDTRLDSRFIDLRRDNVSAIFKIKNRMFHTIRDFFYE
NGFMEINTPKLVASATEGGTELFPITYFEKEAFLGQSPQLYKQMMMSSGMDKVFEIGQIFRAEEHDTLRHLNEAVSIDAE
ASFMDDIDVMKILNNMLEQVIIDINEDCKEELNILEHEMPVPDGPFPVVTYDEAVDIVNSRDVEMSWGEDLSRAGEKALG
DVMGGFYFLTEWPSEIKPFYVMPNSKDPTKAHAFDLMYNNLELSSGATRVHQYDVLVKQIEEKGLNVASFGSYLKAFEYG
MPPHAGWGVGADRLAMVLTGVENIRETVLFPRDRHRLTP
>Mature_439_residues
MQGLLNEWRRTNYTKNVTPDLTGQDVIVMGWVHEIRDLGGIIFVIIRDREGKVQITAPSKKVDAEILEDIRKLRKESVVA
IKGTVQEANQAPTGVEIIPKEINLLNLANQPLPMDPTDKVKAEIDTRLDSRFIDLRRDNVSAIFKIKNRMFHTIRDFFYE
NGFMEINTPKLVASATEGGTELFPITYFEKEAFLGQSPQLYKQMMMSSGMDKVFEIGQIFRAEEHDTLRHLNEAVSIDAE
ASFMDDIDVMKILNNMLEQVIIDINEDCKEELNILEHEMPVPDGPFPVVTYDEAVDIVNSRDVEMSWGEDLSRAGEKALG
DVMGGFYFLTEWPSEIKPFYVMPNSKDPTKAHAFDLMYNNLELSSGATRVHQYDVLVKQIEEKGLNVASFGSYLKAFEYG
MPPHAGWGVGADRLAMVLTGVENIRETVLFPRDRHRLTP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI45439306, Length=452, Percent_Identity=33.8495575221239, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI4758762, Length=438, Percent_Identity=29.9086757990868, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI226491502, Length=446, Percent_Identity=26.6816143497758, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI194272210, Length=470, Percent_Identity=27.8723404255319, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI5031815, Length=470, Percent_Identity=27.8723404255319, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI40789249, Length=259, Percent_Identity=31.6602316602317, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1787161, Length=445, Percent_Identity=26.5168539325843, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1788173, Length=294, Percent_Identity=31.6326530612245, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1790571, Length=478, Percent_Identity=24.4769874476987, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789256, Length=478, Percent_Identity=26.5690376569038, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17551876, Length=475, Percent_Identity=32, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71984122, Length=432, Percent_Identity=29.1666666666667, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI17556372, Length=425, Percent_Identity=26.1176470588235, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994340, Length=476, Percent_Identity=26.0504201680672, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17535925, Length=476, Percent_Identity=26.0504201680672, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17535927, Length=476, Percent_Identity=26.0504201680672, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI32566633, Length=311, Percent_Identity=27.6527331189711, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323011, Length=453, Percent_Identity=30.4635761589404, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6321807, Length=432, Percent_Identity=30.3240740740741, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6319872, Length=462, Percent_Identity=24.025974025974, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325153, Length=248, Percent_Identity=27.0161290322581, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17136276, Length=462, Percent_Identity=32.4675324675325, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI19921528, Length=437, Percent_Identity=29.7482837528604, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI19922416, Length=457, Percent_Identity=25.8205689277899, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24640851, Length=463, Percent_Identity=27.8617710583153, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24640849, Length=463, Percent_Identity=27.8617710583153, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24584738, Length=297, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020780
- InterPro:   IPR004523
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 49883; Mature: 49883

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLLNEWRRTNYTKNVTPDLTGQDVIVMGWVHEIRDLGGIIFVIIRDREGKVQITAPSK
CCHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCEEEEEEECCCCEEEEECCCC
KVDAEILEDIRKLRKESVVAIKGTVQEANQAPTGVEIIPKEINLLNLANQPLPMDPTDKV
CCCHHHHHHHHHHHHCCEEEEECCHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCCHHH
KAEIDTRLDSRFIDLRRDNVSAIFKIKNRMFHTIRDFFYENGFMEINTPKLVASATEGGT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCC
ELFPITYFEKEAFLGQSPQLYKQMMMSSGMDKVFEIGQIFRAEEHDTLRHLNEAVSIDAE
EEEEEEEECHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
ASFMDDIDVMKILNNMLEQVIIDINEDCKEELNILEHEMPVPDGPFPVVTYDEAVDIVNS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHCC
RDVEMSWGEDLSRAGEKALGDVMGGFYFLTEWPSEIKPFYVMPNSKDPTKAHAFDLMYNN
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHCCC
LELSSGATRVHQYDVLVKQIEEKGLNVASFGSYLKAFEYGMPPHAGWGVGADRLAMVLTG
EECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
VENIRETVLFPRDRHRLTP
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQGLLNEWRRTNYTKNVTPDLTGQDVIVMGWVHEIRDLGGIIFVIIRDREGKVQITAPSK
CCHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCEEEEEEECCCCEEEEECCCC
KVDAEILEDIRKLRKESVVAIKGTVQEANQAPTGVEIIPKEINLLNLANQPLPMDPTDKV
CCCHHHHHHHHHHHHCCEEEEECCHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCCHHH
KAEIDTRLDSRFIDLRRDNVSAIFKIKNRMFHTIRDFFYENGFMEINTPKLVASATEGGT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCC
ELFPITYFEKEAFLGQSPQLYKQMMMSSGMDKVFEIGQIFRAEEHDTLRHLNEAVSIDAE
EEEEEEEECHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
ASFMDDIDVMKILNNMLEQVIIDINEDCKEELNILEHEMPVPDGPFPVVTYDEAVDIVNS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHCC
RDVEMSWGEDLSRAGEKALGDVMGGFYFLTEWPSEIKPFYVMPNSKDPTKAHAFDLMYNN
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHCCC
LELSSGATRVHQYDVLVKQIEEKGLNVASFGSYLKAFEYGMPPHAGWGVGADRLAMVLTG
EECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
VENIRETVLFPRDRHRLTP
HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA