Click here to switch to the map view.

The map label for this gene is argS

Identifier: 148643291

GI number: 148643291

Start: 1232922

End: 1234649

Strand: Reverse

Name: argS

Synonym: Msm_1231

Alternate gene names: 148643291

Gene position: 1234649-1232922 (Counterclockwise)

Preceding gene: 148643292

Following gene: 148643287

Centisome position: 66.62

GC content: 32.29

Gene sequence:

>1728_bases
ATGTATTTTGAGATAGAAAAACAAGCAATTGATGCTATAAGTGATGCTTTAGACAAGTTTGAAGTAGATAATACTTTAGA
AAATTTTCAGGTTGAAGATGAAAAGAATTTTAGATTAGAATTTCCACCAAATCCGGACATGGGAGATTTAGCTAGTACTA
TTGCATTTTCACTTGCTAAAAAATTAAGGAAAGCTCCTAATCTTATAGCTTCTGAAATTGTAGAAAAACTTGAAATTCCT
GAAATATTTGAAAAAGTGGAAGCTATTGGCCCATATGTCAATTTCTTTATTGATTACTCAAATTTTTCTAAAAAGCTTTT
AGAGTATGTCGGAAAAGATTATGGTCATCTTCCAAAGGCAGATGAAAAAATAATATTGGAACACACTTCAGCTAATCCTA
ACGGTCCATTGCACATTGGGCATGTAAGGAATTCTATTTTTGGTGATTCCTTAAATCGTCTTTTAAAAGTAGCTGGTAGG
GAAGTTGAAACTCAGTATTATGTAAATGATATGGGAAGACAGATAGCTATTATTGTATTTGGAATTACCGAACTTGGTTT
GAAAATTGAAGATCAGGAAGGAGATAAAATCGACCATAAGATTGGAAGATTATATTTCAAAGCTAATCAAAAATTAAACG
AAGATGAAAGTTTAGTTTCACATGTAGATAATTTGATTGAAAGATATGAAGGTGGAGCAGAACCTGAATTAAATAAAATA
TTCGAAGAAGTAGTTGAAAGTTGTCTTTTAGGAATTAAGGAAACACTTCATAGAATCAATATAAACCACGATGATTTTGT
ATGGGAAGGTCAGTTTGTAAGAAGTGGTGAAGTGGATGACATGATTAAATACTTTGACCATGAAGGATTTGTCTCATATG
GTGATGTAACTTATATTGATTTAACCTGCTTCCAAATTGAAAAAGAATTTGTACTTAGAAGGTCTGACGGCACTTCACTT
TACTCAACAAGAGATTTAGCTTATCACAGATACAAAGCTACTCAGGGGGATGTGGTTTTAGATATTTTAGGTTCAGACCA
TAAATTAGCAGCTCAACAGATTAATGTAATCTTTAAAGAGATTTTAAGAGAAATTCCTCCTGAAGTTATATTCTATGAAT
TTATTACACTTCCTTCAGGATCCATGTCTACAAGAAAAGGAGTATTTGTTTCAGTTGATGAATTGGTTGATGAAGCTGTA
AAAAGAGCAGCTGATGAAATTAAATCCAGAAACCCTGATTTAACTGATGAAGAAATTAAACCGATGGCTGAAGATATTGG
TGTTGGAGCTATCAGGTTCTTTATAGCTAAATTATCTCCTGAAAAACACTTAACCTTTAAATGGGATGAAGCATTAAGCT
TTGAGCGAGGATGTGCTTCTATTCAATATGCTCATGCAAGAGCATGCAAATTACTTAAAAAATCCGGTAAGGATGTATCT
TCTTTAGCTGTATCTGATGACTGGGTTCCTAATGAAAATGAAAAAGATTTAATTAGGACAATAGCTAAGTTCCCACAGGT
TATTGAAGACTGTGCTAACAAAAAAAGGATTCACAATATTACACAATACTGTCAGGATTTGGCTGGTGCATTTAATAAAT
TCTATAAAGCTGAACAAGTTATTGGTTCAGATGTAGAAGATACAAGACTTGTTTTAGTTGATAGGGCTAAAACTACTTTA
AAAAATGCTTTAGATATTTTAGGAGTTCCAGCTCCTCAAAAAATGTAA

Upstream 100 bases:

>100_bases
AAATGAAAGGGTATTGACTTGGGATGGCCATCCTATTGTTATTCCATATATTGGAAATATTTCTCTTTGGTTAAGAGGTT
TGTAATTTAAAGGTGAGTTA

Downstream 100 bases:

>100_bases
ATGAGTTGTAAAAACTCATTTTTCTTCTCTTTTTACTATAGTTGAATATATTTTTTTAAGTGTGGTTTTAAATTCTTCAA
ACTCTTTTTCACTTAAATTT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MYFEIEKQAIDAISDALDKFEVDNTLENFQVEDEKNFRLEFPPNPDMGDLASTIAFSLAKKLRKAPNLIASEIVEKLEIP
EIFEKVEAIGPYVNFFIDYSNFSKKLLEYVGKDYGHLPKADEKIILEHTSANPNGPLHIGHVRNSIFGDSLNRLLKVAGR
EVETQYYVNDMGRQIAIIVFGITELGLKIEDQEGDKIDHKIGRLYFKANQKLNEDESLVSHVDNLIERYEGGAEPELNKI
FEEVVESCLLGIKETLHRININHDDFVWEGQFVRSGEVDDMIKYFDHEGFVSYGDVTYIDLTCFQIEKEFVLRRSDGTSL
YSTRDLAYHRYKATQGDVVLDILGSDHKLAAQQINVIFKEILREIPPEVIFYEFITLPSGSMSTRKGVFVSVDELVDEAV
KRAADEIKSRNPDLTDEEIKPMAEDIGVGAIRFFIAKLSPEKHLTFKWDEALSFERGCASIQYAHARACKLLKKSGKDVS
SLAVSDDWVPNENEKDLIRTIAKFPQVIEDCANKKRIHNITQYCQDLAGAFNKFYKAEQVIGSDVEDTRLVLVDRAKTTL
KNALDILGVPAPQKM

Sequences:

>Translated_575_residues
MYFEIEKQAIDAISDALDKFEVDNTLENFQVEDEKNFRLEFPPNPDMGDLASTIAFSLAKKLRKAPNLIASEIVEKLEIP
EIFEKVEAIGPYVNFFIDYSNFSKKLLEYVGKDYGHLPKADEKIILEHTSANPNGPLHIGHVRNSIFGDSLNRLLKVAGR
EVETQYYVNDMGRQIAIIVFGITELGLKIEDQEGDKIDHKIGRLYFKANQKLNEDESLVSHVDNLIERYEGGAEPELNKI
FEEVVESCLLGIKETLHRININHDDFVWEGQFVRSGEVDDMIKYFDHEGFVSYGDVTYIDLTCFQIEKEFVLRRSDGTSL
YSTRDLAYHRYKATQGDVVLDILGSDHKLAAQQINVIFKEILREIPPEVIFYEFITLPSGSMSTRKGVFVSVDELVDEAV
KRAADEIKSRNPDLTDEEIKPMAEDIGVGAIRFFIAKLSPEKHLTFKWDEALSFERGCASIQYAHARACKLLKKSGKDVS
SLAVSDDWVPNENEKDLIRTIAKFPQVIEDCANKKRIHNITQYCQDLAGAFNKFYKAEQVIGSDVEDTRLVLVDRAKTTL
KNALDILGVPAPQKM
>Mature_575_residues
MYFEIEKQAIDAISDALDKFEVDNTLENFQVEDEKNFRLEFPPNPDMGDLASTIAFSLAKKLRKAPNLIASEIVEKLEIP
EIFEKVEAIGPYVNFFIDYSNFSKKLLEYVGKDYGHLPKADEKIILEHTSANPNGPLHIGHVRNSIFGDSLNRLLKVAGR
EVETQYYVNDMGRQIAIIVFGITELGLKIEDQEGDKIDHKIGRLYFKANQKLNEDESLVSHVDNLIERYEGGAEPELNKI
FEEVVESCLLGIKETLHRININHDDFVWEGQFVRSGEVDDMIKYFDHEGFVSYGDVTYIDLTCFQIEKEFVLRRSDGTSL
YSTRDLAYHRYKATQGDVVLDILGSDHKLAAQQINVIFKEILREIPPEVIFYEFITLPSGSMSTRKGVFVSVDELVDEAV
KRAADEIKSRNPDLTDEEIKPMAEDIGVGAIRFFIAKLSPEKHLTFKWDEALSFERGCASIQYAHARACKLLKKSGKDVS
SLAVSDDWVPNENEKDLIRTIAKFPQVIEDCANKKRIHNITQYCQDLAGAFNKFYKAEQVIGSDVEDTRLVLVDRAKTTL
KNALDILGVPAPQKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=592, Percent_Identity=23.9864864864865, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI197100773, Length=536, Percent_Identity=22.2014925373134, Blast_Score=93, Evalue=6e-19,
Organism=Escherichia coli, GI1788184, Length=550, Percent_Identity=26, Blast_Score=174, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71985061, Length=576, Percent_Identity=21.7013888888889, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71985068, Length=536, Percent_Identity=21.455223880597, Blast_Score=89, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6320548, Length=564, Percent_Identity=26.5957446808511, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6321883, Length=559, Percent_Identity=26.654740608229, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI18859963, Length=571, Percent_Identity=23.6427320490368, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28571570, Length=483, Percent_Identity=22.7743271221532, Blast_Score=106, Evalue=5e-23,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_METS3 (A5UMK8)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273804.1
- ProteinModelPortal:   A5UMK8
- SMR:   A5UMK8
- STRING:   A5UMK8
- GeneID:   5216015
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_1231
- eggNOG:   arNOG04487
- HOGENOM:   HBG695395
- OMA:   NDMGRQI
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65339; Mature: 65339

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFEIEKQAIDAISDALDKFEVDNTLENFQVEDEKNFRLEFPPNPDMGDLASTIAFSLAK
CCEEEHHHHHHHHHHHHHHHHHCCHHHCCEECCCCCEEEECCCCCCHHHHHHHHHHHHHH
KLRKAPNLIASEIVEKLEIPEIFEKVEAIGPYVNFFIDYSNFSKKLLEYVGKDYGHLPKA
HHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHEEEEHHHHHHHHHHHHCCCCCCCCCC
DEKIILEHTSANPNGPLHIGHVRNSIFGDSLNRLLKVAGREVETQYYVNDMGRQIAIIVF
CCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEE
GITELGLKIEDQEGDKIDHKIGRLYFKANQKLNEDESLVSHVDNLIERYEGGAEPELNKI
EHHHHCCEEECCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
FEEVVESCLLGIKETLHRININHDDFVWEGQFVRSGEVDDMIKYFDHEGFVSYGDVTYID
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEECCCCHHHHHHHHCCCCCEEECCEEEEE
LTCFQIEKEFVLRRSDGTSLYSTRDLAYHRYKATQGDVVLDILGSDHKLAAQQINVIFKE
EEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHH
ILREIPPEVIFYEFITLPSGSMSTRKGVFVSVDELVDEAVKRAADEIKSRNPDLTDEEIK
HHHHCCCHHEEHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
PMAEDIGVGAIRFFIAKLSPEKHLTFKWDEALSFERGCASIQYAHARACKLLKKSGKDVS
HHHHHCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHH
SLAVSDDWVPNENEKDLIRTIAKFPQVIEDCANKKRIHNITQYCQDLAGAFNKFYKAEQV
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGSDVEDTRLVLVDRAKTTLKNALDILGVPAPQKM
HCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MYFEIEKQAIDAISDALDKFEVDNTLENFQVEDEKNFRLEFPPNPDMGDLASTIAFSLAK
CCEEEHHHHHHHHHHHHHHHHHCCHHHCCEECCCCCEEEECCCCCCHHHHHHHHHHHHHH
KLRKAPNLIASEIVEKLEIPEIFEKVEAIGPYVNFFIDYSNFSKKLLEYVGKDYGHLPKA
HHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHEEEEHHHHHHHHHHHHCCCCCCCCCC
DEKIILEHTSANPNGPLHIGHVRNSIFGDSLNRLLKVAGREVETQYYVNDMGRQIAIIVF
CCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEE
GITELGLKIEDQEGDKIDHKIGRLYFKANQKLNEDESLVSHVDNLIERYEGGAEPELNKI
EHHHHCCEEECCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
FEEVVESCLLGIKETLHRININHDDFVWEGQFVRSGEVDDMIKYFDHEGFVSYGDVTYID
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEECCCCHHHHHHHHCCCCCEEECCEEEEE
LTCFQIEKEFVLRRSDGTSLYSTRDLAYHRYKATQGDVVLDILGSDHKLAAQQINVIFKE
EEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHH
ILREIPPEVIFYEFITLPSGSMSTRKGVFVSVDELVDEAVKRAADEIKSRNPDLTDEEIK
HHHHCCCHHEEHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
PMAEDIGVGAIRFFIAKLSPEKHLTFKWDEALSFERGCASIQYAHARACKLLKKSGKDVS
HHHHHCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHH
SLAVSDDWVPNENEKDLIRTIAKFPQVIEDCANKKRIHNITQYCQDLAGAFNKFYKAEQV
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGSDVEDTRLVLVDRAKTTLKNALDILGVPAPQKM
HCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA