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The map label for this gene is ilvE [H]

Identifier: 148643262

GI number: 148643262

Start: 1201877

End: 1202800

Strand: Reverse

Name: ilvE [H]

Synonym: Msm_1202

Alternate gene names: 148643262

Gene position: 1202800-1201877 (Counterclockwise)

Preceding gene: 148643265

Following gene: 148643261

Centisome position: 64.91

GC content: 34.85

Gene sequence:

>924_bases
ATGGCATGGGACGATTCTGCTAGTAAAATATGGATGGACGGAAACATGGTTGATTGGAAAGATGCAAAAATTCATGCTCT
TTCACATGTAGTCCATTATGGTACAAGTGTTTTTGAAGGTATTAGAGCATATGACAATAAAAAAGGCACTTGTATTTTTC
GTTTAAATGAACATGTAAAACGTTTATTTAATTCAGCAAAAGTTTATAAAATTGATATTCCTTATACTCAAGAAGAAATT
GCACAGGCAATTAGGGATACTGTTAAAATCAATGAGTTAGCTTCCTGTTACATACGTCCTATTGTATTTAGAGGATATGG
TCAGTTAGGAGTTAATCCGTTATCCTGTCCTGTTAATACTGTAATTGCTGCTTGGGAATGGGGATCTTATTTAGGTGAGG
AAGGAATGGCTAACGGTGTAGATGTTGGAGTTTCATCCTGGAGAAAACCAGCTCCGGATACTTTCCCAACATTAGCTAAA
TGTGGTGCTAATTATATGAATTCTCAATTAGCTAAACTGGAAGCTATTGACCATGGTTATGAGGAAGCTATCATGCTTGA
TTATGAAGGGCATGTTTCTGAAGGTAGTGGGGAAAACATTTTCATTATTGAAGATGGAGTATTATACACTCCTTCAATGG
ATTCTTCCAATCTTAAAGGAATTACAAGGGAATCTATTAAACAATTGGCCAATGATTTAGGCTATGAAGTAGTTGAAGAA
AGAATTTCAAGAGAAAGATTATATTTTGCTGATGAAGTATTTTTCAGCGGAACTGCTGCTGAAGTTACTCCTATCCGTTC
AATTGATCATAAAATCATTGGTGCAGGTAAAAGAGGTCCAATTTCAGAAGAATTACAAAAAACTTTCTTTGACATTGTTG
AAGGCAAAAAAGAAGATAAATTTGGCTGGTTGGATTACGTTTAA

Upstream 100 bases:

>100_bases
TTACTTTGTGTATAAAATTCGCATCTGTCTGATAAGTAAGTTATAAATAAAAATAACACTATAATATACACTAATGAATT
ATTAATTGAAAGTGATATAA

Downstream 100 bases:

>100_bases
ATGGTGTGAGAAATGGATATAATTCAGGCAATTATTATTGGTATTGTTCAGGGATTAACTGAGTTCTTACCTGTAAGTAG
TTCAGCTCATTTAATCTTTG

Product: branched-chain-amino-acid aminotransferase, IlvE

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MAWDDSASKIWMDGNMVDWKDAKIHALSHVVHYGTSVFEGIRAYDNKKGTCIFRLNEHVKRLFNSAKVYKIDIPYTQEEI
AQAIRDTVKINELASCYIRPIVFRGYGQLGVNPLSCPVNTVIAAWEWGSYLGEEGMANGVDVGVSSWRKPAPDTFPTLAK
CGANYMNSQLAKLEAIDHGYEEAIMLDYEGHVSEGSGENIFIIEDGVLYTPSMDSSNLKGITRESIKQLANDLGYEVVEE
RISRERLYFADEVFFSGTAAEVTPIRSIDHKIIGAGKRGPISEELQKTFFDIVEGKKEDKFGWLDYV

Sequences:

>Translated_307_residues
MAWDDSASKIWMDGNMVDWKDAKIHALSHVVHYGTSVFEGIRAYDNKKGTCIFRLNEHVKRLFNSAKVYKIDIPYTQEEI
AQAIRDTVKINELASCYIRPIVFRGYGQLGVNPLSCPVNTVIAAWEWGSYLGEEGMANGVDVGVSSWRKPAPDTFPTLAK
CGANYMNSQLAKLEAIDHGYEEAIMLDYEGHVSEGSGENIFIIEDGVLYTPSMDSSNLKGITRESIKQLANDLGYEVVEE
RISRERLYFADEVFFSGTAAEVTPIRSIDHKIIGAGKRGPISEELQKTFFDIVEGKKEDKFGWLDYV
>Mature_306_residues
AWDDSASKIWMDGNMVDWKDAKIHALSHVVHYGTSVFEGIRAYDNKKGTCIFRLNEHVKRLFNSAKVYKIDIPYTQEEIA
QAIRDTVKINELASCYIRPIVFRGYGQLGVNPLSCPVNTVIAAWEWGSYLGEEGMANGVDVGVSSWRKPAPDTFPTLAKC
GANYMNSQLAKLEAIDHGYEEAIMLDYEGHVSEGSGENIFIIEDGVLYTPSMDSSNLKGITRESIKQLANDLGYEVVEER
ISRERLYFADEVFFSGTAAEVTPIRSIDHKIIGAGKRGPISEELQKTFFDIVEGKKEDKFGWLDYV

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI296010904, Length=321, Percent_Identity=28.9719626168224, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI38176287, Length=321, Percent_Identity=28.9719626168224, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI296010906, Length=321, Percent_Identity=28.9719626168224, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI296010902, Length=278, Percent_Identity=29.8561151079137, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI296010900, Length=278, Percent_Identity=29.8561151079137, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI48994963, Length=302, Percent_Identity=51.9867549668874, Blast_Score=339, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6322608, Length=339, Percent_Identity=25.9587020648968, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322002, Length=294, Percent_Identity=27.2108843537415, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34459; Mature: 34328

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWDDSASKIWMDGNMVDWKDAKIHALSHVVHYGTSVFEGIRAYDNKKGTCIFRLNEHVK
CCCCCCCCEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHH
RLFNSAKVYKIDIPYTQEEIAQAIRDTVKINELASCYIRPIVFRGYGQLGVNPLSCPVNT
HHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHH
VIAAWEWGSYLGEEGMANGVDVGVSSWRKPAPDTFPTLAKCGANYMNSQLAKLEAIDHGY
HEEHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCC
EEAIMLDYEGHVSEGSGENIFIIEDGVLYTPSMDSSNLKGITRESIKQLANDLGYEVVEE
CCEEEEEECCCCCCCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHHHH
RISRERLYFADEVFFSGTAAEVTPIRSIDHKIIGAGKRGPISEELQKTFFDIVEGKKEDK
HHHHHHHHHHHHHHCCCCCCCCCHHHHHCHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCC
FGWLDYV
CCCCCCC
>Mature Secondary Structure 
AWDDSASKIWMDGNMVDWKDAKIHALSHVVHYGTSVFEGIRAYDNKKGTCIFRLNEHVK
CCCCCCCEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHH
RLFNSAKVYKIDIPYTQEEIAQAIRDTVKINELASCYIRPIVFRGYGQLGVNPLSCPVNT
HHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHH
VIAAWEWGSYLGEEGMANGVDVGVSSWRKPAPDTFPTLAKCGANYMNSQLAKLEAIDHGY
HEEHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCC
EEAIMLDYEGHVSEGSGENIFIIEDGVLYTPSMDSSNLKGITRESIKQLANDLGYEVVEE
CCEEEEEECCCCCCCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHHHH
RISRERLYFADEVFFSGTAAEVTPIRSIDHKIIGAGKRGPISEELQKTFFDIVEGKKEDK
HHHHHHHHHHHHHHCCCCCCCCCHHHHHCHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCC
FGWLDYV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]