Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 148643261

GI number: 148643261

Start: 1201031

End: 1201864

Strand: Reverse

Name: uppP

Synonym: Msm_1201

Alternate gene names: 148643261

Gene position: 1201864-1201031 (Counterclockwise)

Preceding gene: 148643262

Following gene: 148643258

Centisome position: 64.85

GC content: 31.65

Gene sequence:

>834_bases
ATGGATATAATTCAGGCAATTATTATTGGTATTGTTCAGGGATTAACTGAGTTCTTACCTGTAAGTAGTTCAGCTCATTT
AATCTTTGCTCAAAATGCATTAGGGGTAGAATCCTCTCTTGCTTTTGATGTTTTTCTTCATTTAGGAAGTTTAATAGCTG
TATTATGGTTCTTCCGTGCAGATATTATCAGAATGATTCAGGCATTCTTATTAAGTATTGGAGATATTATTCAGCACAGA
TTTAAGGAAGGATTTTACTCTGATCCTTATAAAAGATTGGTCTGGTATGTAATTATAGCTACTATTCCTGTAGGTTTAGT
TGGTGTATTATTTGAAAGTCAGGTAGAGTCATTGTTTGCAGGTGCATTATATGTTCCGGCATTTTTCTTATTTGTAACAG
GTACTATTCTTTACTTATCTCAAAGAATGAATTCTGGTGAGGTTGATTTATCAAATCTTTCACTTAAAGAATCAATATTT
ATGGGATTAGGTCAGGCATGTGCTATATTGCCGGGGCTTTCACGTTCAGGTACTACAATAGCTGCAGGACTTGTAATAGG
ATTAGATAAAGAATTTGCTGCTAAATTCAGTTTTATATTATCTATTCCAGCTATTTTGGGAGCATTTGTAGTTCAACTTA
AAGATATTGGAACAATCACAGATTTCAATGCTTTAGCTATTTTATTCGGATTTTTAGCAGCATTAATATCTGGTTATTTG
GCTATTAAATGGTTACTTGAATTAATTCAAAAAAGAAGTTTGGATATTTTTGCATATTATTGTTGGATTGTAGGAATAAT
AGTATTTATGGGTTCAATAACCCATTTATTCTAA

Upstream 100 bases:

>100_bases
TCCAATTTCAGAAGAATTACAAAAAACTTTCTTTGACATTGTTGAAGGCAAAAAAGAAGATAAATTTGGCTGGTTGGATT
ACGTTTAAATGGTGTGAGAA

Downstream 100 bases:

>100_bases
ATACTATTCACTGCAAACCTTTTCTATTTTTTTTCTTAATCTTTCAACAGAGTTTCCTCTAATTAATGCTGTAAACATTG
CACCGCCGGCCCCAACACCT

Product: undecaprenyl-diphosphatase, UppP

Products: NA

Alternate protein names: Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MDIIQAIIIGIVQGLTEFLPVSSSAHLIFAQNALGVESSLAFDVFLHLGSLIAVLWFFRADIIRMIQAFLLSIGDIIQHR
FKEGFYSDPYKRLVWYVIIATIPVGLVGVLFESQVESLFAGALYVPAFFLFVTGTILYLSQRMNSGEVDLSNLSLKESIF
MGLGQACAILPGLSRSGTTIAAGLVIGLDKEFAAKFSFILSIPAILGAFVVQLKDIGTITDFNALAILFGFLAALISGYL
AIKWLLELIQKRSLDIFAYYCWIVGIIVFMGSITHLF

Sequences:

>Translated_277_residues
MDIIQAIIIGIVQGLTEFLPVSSSAHLIFAQNALGVESSLAFDVFLHLGSLIAVLWFFRADIIRMIQAFLLSIGDIIQHR
FKEGFYSDPYKRLVWYVIIATIPVGLVGVLFESQVESLFAGALYVPAFFLFVTGTILYLSQRMNSGEVDLSNLSLKESIF
MGLGQACAILPGLSRSGTTIAAGLVIGLDKEFAAKFSFILSIPAILGAFVVQLKDIGTITDFNALAILFGFLAALISGYL
AIKWLLELIQKRSLDIFAYYCWIVGIIVFMGSITHLF
>Mature_277_residues
MDIIQAIIIGIVQGLTEFLPVSSSAHLIFAQNALGVESSLAFDVFLHLGSLIAVLWFFRADIIRMIQAFLLSIGDIIQHR
FKEGFYSDPYKRLVWYVIIATIPVGLVGVLFESQVESLFAGALYVPAFFLFVTGTILYLSQRMNSGEVDLSNLSLKESIF
MGLGQACAILPGLSRSGTTIAAGLVIGLDKEFAAKFSFILSIPAILGAFVVQLKDIGTITDFNALAILFGFLAALISGYL
AIKWLLELIQKRSLDIFAYYCWIVGIIVFMGSITHLF

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=273, Percent_Identity=33.6996336996337, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_METS3 (A5UMH8)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273774.1
- STRING:   A5UMH8
- GeneID:   5217173
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_1201
- eggNOG:   arNOG11592
- HOGENOM:   HBG391969
- OMA:   HSMYWFV
- ProtClustDB:   CLSK843600
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30381; Mature: 30381

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17e30ba8)-; HASH(0x16accfd0)-; HASH(0x196a6c94)-; HASH(0x196b6c44)-; HASH(0x4085695c)-; HASH(0x19668efc)-; HASH(0x40857088)-; HASH(0x19187140)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIQAIIIGIVQGLTEFLPVSSSAHLIFAQNALGVESSLAFDVFLHLGSLIAVLWFFRA
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DIIRMIQAFLLSIGDIIQHRFKEGFYSDPYKRLVWYVIIATIPVGLVGVLFESQVESLFA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALYVPAFFLFVTGTILYLSQRMNSGEVDLSNLSLKESIFMGLGQACAILPGLSRSGTTI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
AAGLVIGLDKEFAAKFSFILSIPAILGAFVVQLKDIGTITDFNALAILFGFLAALISGYL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AIKWLLELIQKRSLDIFAYYCWIVGIIVFMGSITHLF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDIIQAIIIGIVQGLTEFLPVSSSAHLIFAQNALGVESSLAFDVFLHLGSLIAVLWFFRA
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DIIRMIQAFLLSIGDIIQHRFKEGFYSDPYKRLVWYVIIATIPVGLVGVLFESQVESLFA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALYVPAFFLFVTGTILYLSQRMNSGEVDLSNLSLKESIFMGLGQACAILPGLSRSGTTI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
AAGLVIGLDKEFAAKFSFILSIPAILGAFVVQLKDIGTITDFNALAILFGFLAALISGYL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AIKWLLELIQKRSLDIFAYYCWIVGIIVFMGSITHLF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA