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The map label for this gene is mreB [H]

Identifier: 148643040

GI number: 148643040

Start: 940290

End: 941363

Strand: Reverse

Name: mreB [H]

Synonym: Msm_0980

Alternate gene names: 148643040

Gene position: 941363-940290 (Counterclockwise)

Preceding gene: 148643041

Following gene: 148643039

Centisome position: 50.8

GC content: 35.29

Gene sequence:

>1074_bases
ATGAATATTTTTGGAAATGAAGAAGAGGAATCACAAGTTAATGATACTAGAATCATTAGTAACAGCTTGGGAATAGATTT
AGGAACTTTAAACACTGTAATTGCAAAACCATCTGGAGATAAATTTGATTTATATCAAATTCCATCAGTTGTTGCTGTTA
AAAAAGATGATCCGTCTGAAGTTTTAGCAGTTGGGGAAGAAGCTAAAAAAATGCTTGGTAGAACTCCTGAAGATATTCTT
GCTGTAAGACCTTTGAAAAAAGGAGTCATTGAAAACGTAGCTCAAGCACAAGCTTTACTTATTAAAGCTATGCAAATTGG
TATAGAAGAGGGGGAAAGTGTTGGAAGAATCGTTATTGGTATTCCTGGAGATTCCTCTGAAGTAGAAAAAAATGCAGCTG
AAGAGATTGGTAGGAAAGCTGGAGCAGAAAACATTCTTGTAATTAGTGAAGGATTGGCAGCAGCTATTGGTGCAGGTTTA
CCTATTGCTGAACCAAACGGAACTATGGTTATTGATATTGGTGCAGGATCAACAGATATTGTTATCATTTCCCTTGGTGG
TATTAACGATATTGAAACAGTTAGATGCGGTGGAGATGACATTGATAACAGAATAGTTGAATTGGTTGCAGAAAAATATA
ATGTAGCTATTGGTATTCATGATGCAGAATCTGCAAAAATAGAAGTTGGTATGATTCACTGTAGCGAACAACTTGAAAAC
TTAAGTGTTGAAGTTATTGGTAAATCATTAGAAACCAACAGGCCTAAAAAAGTTGTCATCGACTCAATGTTAGTTGCTGA
TGCTGTAGAACCATTTATGCAAGAAATTGTAGATGGTTTAAATGTTATTTTAGAAAGATTATCTCCTGAATTGATGATGG
GTGTTTATAATAATGCAGTGGCAGTTGGAGGAAGTTCAAGACTCCGTGGATTAAAAGAAAGGGTTTTCGATGAAATATCT
ATTCCTATTGAAGTTTCTGATGATCCTATGACTGTTGTAGCAAAAGGTACTGCTATTGTAGCTGCAGAACCTCTTGCATT
AGAACCTGAAGTTCGTCTTAGAGCTATGAAATAA

Upstream 100 bases:

>100_bases
CAGTTGAAAAAGATGAGGATATTGAAAAAGTCCAGAGTATAGCTACATCTAATAGGATATTTGTCATTGATTTTAAAGAT
ATTGTAACGGAGGATTAGTC

Downstream 100 bases:

>100_bases
TTTTTTCAATTATTTCTTTTTTAACTTTTTTTGCGCTGATTTTTATGGATGTATTGGGAATTGATGAAGCAGGTCGGGGA
TCTGTTTTAGGACCATTGGT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MNIFGNEEEESQVNDTRIISNSLGIDLGTLNTVIAKPSGDKFDLYQIPSVVAVKKDDPSEVLAVGEEAKKMLGRTPEDIL
AVRPLKKGVIENVAQAQALLIKAMQIGIEEGESVGRIVIGIPGDSSEVEKNAAEEIGRKAGAENILVISEGLAAAIGAGL
PIAEPNGTMVIDIGAGSTDIVIISLGGINDIETVRCGGDDIDNRIVELVAEKYNVAIGIHDAESAKIEVGMIHCSEQLEN
LSVEVIGKSLETNRPKKVVIDSMLVADAVEPFMQEIVDGLNVILERLSPELMMGVYNNAVAVGGSSRLRGLKERVFDEIS
IPIEVSDDPMTVVAKGTAIVAAEPLALEPEVRLRAMK

Sequences:

>Translated_357_residues
MNIFGNEEEESQVNDTRIISNSLGIDLGTLNTVIAKPSGDKFDLYQIPSVVAVKKDDPSEVLAVGEEAKKMLGRTPEDIL
AVRPLKKGVIENVAQAQALLIKAMQIGIEEGESVGRIVIGIPGDSSEVEKNAAEEIGRKAGAENILVISEGLAAAIGAGL
PIAEPNGTMVIDIGAGSTDIVIISLGGINDIETVRCGGDDIDNRIVELVAEKYNVAIGIHDAESAKIEVGMIHCSEQLEN
LSVEVIGKSLETNRPKKVVIDSMLVADAVEPFMQEIVDGLNVILERLSPELMMGVYNNAVAVGGSSRLRGLKERVFDEIS
IPIEVSDDPMTVVAKGTAIVAAEPLALEPEVRLRAMK
>Mature_357_residues
MNIFGNEEEESQVNDTRIISNSLGIDLGTLNTVIAKPSGDKFDLYQIPSVVAVKKDDPSEVLAVGEEAKKMLGRTPEDIL
AVRPLKKGVIENVAQAQALLIKAMQIGIEEGESVGRIVIGIPGDSSEVEKNAAEEIGRKAGAENILVISEGLAAAIGAGL
PIAEPNGTMVIDIGAGSTDIVIISLGGINDIETVRCGGDDIDNRIVELVAEKYNVAIGIHDAESAKIEVGMIHCSEQLEN
LSVEVIGKSLETNRPKKVVIDSMLVADAVEPFMQEIVDGLNVILERLSPELMMGVYNNAVAVGGSSRLRGLKERVFDEIS
IPIEVSDDPMTVVAKGTAIVAAEPLALEPEVRLRAMK

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=329, Percent_Identity=37.6899696048632, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1786196, Length=384, Percent_Identity=24.21875, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786870, Length=363, Percent_Identity=23.9669421487603, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323401, Length=390, Percent_Identity=24.8717948717949, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37876; Mature: 37876

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFGNEEEESQVNDTRIISNSLGIDLGTLNTVIAKPSGDKFDLYQIPSVVAVKKDDPSE
CCCCCCCCHHHHCCCCEEEHHCCCCEECCCEEEEECCCCCEEEHEECCCEEEEECCCHHH
VLAVGEEAKKMLGRTPEDILAVRPLKKGVIENVAQAQALLIKAMQIGIEEGESVGRIVIG
HHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IPGDSSEVEKNAAEEIGRKAGAENILVISEGLAAAIGAGLPIAEPNGTMVIDIGAGSTDI
CCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCCCCCCEEEEEECCCCCCE
VIISLGGINDIETVRCGGDDIDNRIVELVAEKYNVAIGIHDAESAKIEVGMIHCSEQLEN
EEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEEEEHHHHHC
LSVEVIGKSLETNRPKKVVIDSMLVADAVEPFMQEIVDGLNVILERLSPELMMGVYNNAV
CEEEEEECHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCEE
AVGGSSRLRGLKERVFDEISIPIEVSDDPMTVVAKGTAIVAAEPLALEPEVRLRAMK
EECCHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCEEEEEECCCEECCCCEEEECC
>Mature Secondary Structure
MNIFGNEEEESQVNDTRIISNSLGIDLGTLNTVIAKPSGDKFDLYQIPSVVAVKKDDPSE
CCCCCCCCHHHHCCCCEEEHHCCCCEECCCEEEEECCCCCEEEHEECCCEEEEECCCHHH
VLAVGEEAKKMLGRTPEDILAVRPLKKGVIENVAQAQALLIKAMQIGIEEGESVGRIVIG
HHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IPGDSSEVEKNAAEEIGRKAGAENILVISEGLAAAIGAGLPIAEPNGTMVIDIGAGSTDI
CCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCCCCCCEEEEEECCCCCCE
VIISLGGINDIETVRCGGDDIDNRIVELVAEKYNVAIGIHDAESAKIEVGMIHCSEQLEN
EEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEEEEHHHHHC
LSVEVIGKSLETNRPKKVVIDSMLVADAVEPFMQEIVDGLNVILERLSPELMMGVYNNAV
CEEEEEECHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCEE
AVGGSSRLRGLKERVFDEISIPIEVSDDPMTVVAKGTAIVAAEPLALEPEVRLRAMK
EECCHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCEEEEEECCCEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]