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The map label for this gene is sucC [H]

Identifier: 148642984

GI number: 148642984

Start: 887028

End: 888143

Strand: Reverse

Name: sucC [H]

Synonym: Msm_0924

Alternate gene names: 148642984

Gene position: 888143-887028 (Counterclockwise)

Preceding gene: 148642985

Following gene: 148642983

Centisome position: 47.93

GC content: 33.06

Gene sequence:

>1116_bases
ATGAAATTTTTCGAATATATGGCAAAAAGAATTTTTAACGAGGAAGGAATTCCAATTTTAGAAGGGCATGTTGCCAATTC
TGCTGAAGAAGCAACATCTATTGCATCAGATATGGGTGTACCTGTTGCAATAAAATCTCAAGTATTAGTTGGTGGTAGAG
GTAAAGCCGGAGGTATTAAATTTGCAGATAACTCTGGTGAAGCATACAAAGTTGCTGATTCATTGATTGGTAATACAATT
AATGGTGAAAGAGTACATCAGCTTTTAATTGAGAAAAAAGCAAACATTATTAAAGAATTTTTCTTAAGTATATCCATTGA
CAGAGCCAATAAAAAACCGGTTATTATGGTAAGTAATGAAGGTGGGGTTGAAATTGAAAATTTAGCTAAAACAAATCCTG
AAAAGATAATTAAATATCATCCAAATCCTTTAATTGAATTTTTACCATATGAATCCCGTGAAATAGCTCGTAAAATGGGT
GTTCCATCAGAGTTAATATCTCCGATGGGTGATGTAATATACAAATTATATAAATTATTTGAGAAATATGATGCAGAAAC
CGCTGAAATCAATCCATTGGTATTGACTGACGAAGGATTAATAGCTGCTGATGCAAAATTCGTTGTGGAAAATGACTCAT
TATACAGACATCCTGATTTGGTAAAACTTGCACGTTATAAGAAAAAAGCAGTAGATTTCGTTAAATTAGATGGGGATATT
GCAGTTATCGGTAATGGTGCAGGTTTAACATTGACAGGTATGGACATGATTAAATTCCACGGTGGAGAACCTGCTACTTT
CTTAGATATCGGTGGGGGAGCTTCAGAAGAAAGTATTAAAAAATCCCTTAACATAGTACTAAATTATGAACCAGTTAAAG
TAGTATTTTTAAATGTTTTAGGAGGAATTACTAAAGCAGATGATGTTGCTCATGGTGTTGTTGATGCTATTAAGGAATCC
AAAAGCTTAGTATCAATTGTAATTAGGTTAACCGGTACTAATGAGGAAGAAGGTCAAAGAATACTTGAAGAAGCAGGAAT
TCCATATGAAATTTCAATGGAAAAAGCAGCTAAAAAAGCTGTTGAGCTTTGTAATAAAATTAAGGCTGAAGAATGA

Upstream 100 bases:

>100_bases
TGCGGCTATTGAATCAATTAAAGCTAGTGTTCCTGCAGGAACTGAAGATAAAAACATAGCTGCTTTTGAAGCAGGATATA
ATTTCTAATTAGGTGTTATA

Downstream 100 bases:

>100_bases
AATTTTTTGCCATAAATGGTAGTCACAGAAAAGATGGAAATACTGCTCAGCTTTTAGAAAAAGCTTTGGAAGGAATAAAA
TCAGTTTGCAGTGATGCTGA

Product: succinyl-CoA synthetase, beta subunit, SucC

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKFFEYMAKRIFNEEGIPILEGHVANSAEEATSIASDMGVPVAIKSQVLVGGRGKAGGIKFADNSGEAYKVADSLIGNTI
NGERVHQLLIEKKANIIKEFFLSISIDRANKKPVIMVSNEGGVEIENLAKTNPEKIIKYHPNPLIEFLPYESREIARKMG
VPSELISPMGDVIYKLYKLFEKYDAETAEINPLVLTDEGLIAADAKFVVENDSLYRHPDLVKLARYKKKAVDFVKLDGDI
AVIGNGAGLTLTGMDMIKFHGGEPATFLDIGGGASEESIKKSLNIVLNYEPVKVVFLNVLGGITKADDVAHGVVDAIKES
KSLVSIVIRLTGTNEEEGQRILEEAGIPYEISMEKAAKKAVELCNKIKAEE

Sequences:

>Translated_371_residues
MKFFEYMAKRIFNEEGIPILEGHVANSAEEATSIASDMGVPVAIKSQVLVGGRGKAGGIKFADNSGEAYKVADSLIGNTI
NGERVHQLLIEKKANIIKEFFLSISIDRANKKPVIMVSNEGGVEIENLAKTNPEKIIKYHPNPLIEFLPYESREIARKMG
VPSELISPMGDVIYKLYKLFEKYDAETAEINPLVLTDEGLIAADAKFVVENDSLYRHPDLVKLARYKKKAVDFVKLDGDI
AVIGNGAGLTLTGMDMIKFHGGEPATFLDIGGGASEESIKKSLNIVLNYEPVKVVFLNVLGGITKADDVAHGVVDAIKES
KSLVSIVIRLTGTNEEEGQRILEEAGIPYEISMEKAAKKAVELCNKIKAEE
>Mature_371_residues
MKFFEYMAKRIFNEEGIPILEGHVANSAEEATSIASDMGVPVAIKSQVLVGGRGKAGGIKFADNSGEAYKVADSLIGNTI
NGERVHQLLIEKKANIIKEFFLSISIDRANKKPVIMVSNEGGVEIENLAKTNPEKIIKYHPNPLIEFLPYESREIARKMG
VPSELISPMGDVIYKLYKLFEKYDAETAEINPLVLTDEGLIAADAKFVVENDSLYRHPDLVKLARYKKKAVDFVKLDGDI
AVIGNGAGLTLTGMDMIKFHGGEPATFLDIGGGASEESIKKSLNIVLNYEPVKVVFLNVLGGITKADDVAHGVVDAIKES
KSLVSIVIRLTGTNEEEGQRILEEAGIPYEISMEKAAKKAVELCNKIKAEE

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=33.1632653061224, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI157779135, Length=373, Percent_Identity=31.6353887399464, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI294862256, Length=358, Percent_Identity=31.0055865921788, Blast_Score=180, Evalue=1e-45,
Organism=Escherichia coli, GI1786948, Length=366, Percent_Identity=37.431693989071, Blast_Score=254, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI17567829, Length=404, Percent_Identity=31.1881188118812, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17539378, Length=387, Percent_Identity=32.0413436692506, Blast_Score=194, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=34.2569269521411, Blast_Score=212, Evalue=9e-56,
Organism=Drosophila melanogaster, GI21356231, Length=398, Percent_Identity=32.4120603015075, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=31.0432569974555, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=31.0432569974555, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=30.7106598984772, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=30.7106598984772, Blast_Score=183, Evalue=1e-46,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 40480; Mature: 40480

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFEYMAKRIFNEEGIPILEGHVANSAEEATSIASDMGVPVAIKSQVLVGGRGKAGGIK
CCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECEEEECCCCCCCCEE
FADNSGEAYKVADSLIGNTINGERVHQLLIEKKANIIKEFFLSISIDRANKKPVIMVSNE
EECCCCCCEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECC
GGVEIENLAKTNPEKIIKYHPNPLIEFLPYESREIARKMGVPSELISPMGDVIYKLYKLF
CCCEEHHHHCCCHHHEEEECCCCHHEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EKYDAETAEINPLVLTDEGLIAADAKFVVENDSLYRHPDLVKLARYKKKAVDFVKLDGDI
HHHCCCCCCCCEEEEECCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEECCCE
AVIGNGAGLTLTGMDMIKFHGGEPATFLDIGGGASEESIKKSLNIVLNYEPVKVVFLNVL
EEEECCCCEEEECCEEEEECCCCCCEEEECCCCCCHHHHHHCEEEEEECCCHHHHHHHHH
GGITKADDVAHGVVDAIKESKSLVSIVIRLTGTNEEEGQRILEEAGIPYEISMEKAAKKA
CCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHCCCCEEEEHHHHHHHH
VELCNKIKAEE
HHHHHHHCCCC
>Mature Secondary Structure
MKFFEYMAKRIFNEEGIPILEGHVANSAEEATSIASDMGVPVAIKSQVLVGGRGKAGGIK
CCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECEEEECCCCCCCCEE
FADNSGEAYKVADSLIGNTINGERVHQLLIEKKANIIKEFFLSISIDRANKKPVIMVSNE
EECCCCCCEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECC
GGVEIENLAKTNPEKIIKYHPNPLIEFLPYESREIARKMGVPSELISPMGDVIYKLYKLF
CCCEEHHHHCCCHHHEEEECCCCHHEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EKYDAETAEINPLVLTDEGLIAADAKFVVENDSLYRHPDLVKLARYKKKAVDFVKLDGDI
HHHCCCCCCCCEEEEECCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEECCCE
AVIGNGAGLTLTGMDMIKFHGGEPATFLDIGGGASEESIKKSLNIVLNYEPVKVVFLNVL
EEEECCCCEEEECCEEEEECCCCCCEEEECCCCCCHHHHHHCEEEEEECCCHHHHHHHHH
GGITKADDVAHGVVDAIKESKSLVSIVIRLTGTNEEEGQRILEEAGIPYEISMEKAAKKA
CCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHCCCCEEEEHHHHHHHH
VELCNKIKAEE
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]