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The map label for this gene is eIF5A

Identifier: 148642937

GI number: 148642937

Start: 833197

End: 833586

Strand: Reverse

Name: eIF5A

Synonym: Msm_0877

Alternate gene names: 148642937

Gene position: 833586-833197 (Counterclockwise)

Preceding gene: 148642944

Following gene: 148642936

Centisome position: 44.98

GC content: 32.05

Gene sequence:

>390_bases
ATGTCAACAAAAGTTGTAGAGATTAAAACATTAAAAGTTGGTAAATATATCGTATTAGGTGGGGAAGCATCTAAAATCAC
AAGTTTAACTACTTCATCCCCAGGTAAACATGGTGCTGCTAAAGCTAGATTAGAAGCTGTAGGTATTTTCGATAACCAAA
AAAGAAGTATTGTTAAACCTGTAGATACCAAAGTAGATATTCCAATTATCGATAAAAGGGTTGGTCAGGTATTATCTATC
CAAGGTAACAATGTTCAGTTAATGGATATGGAAAACTACGACACTTTAGATTTACCTATGCCTGAAGAATTAAAAGACCA
AATCACTGAAGGTATTGAAGTAGATTACATCGTAGCTTTAGGAAATATGAAAATTATGAGAACTAAATAA

Upstream 100 bases:

>100_bases
AATTTATATAAAATGTTGGATAGAATTATTATTAATCTAAAATAATTCTTATTATAGATTACTTATTTAAATCTATTTTT
TAATTTATGGAGGAAAATTA

Downstream 100 bases:

>100_bases
TTTTATTTAGTTCTTTTTTGATTTATTATGCTTTTAAACACATATGAACCATGGAAATTTGCTTTTTCCCAGGAAGAAAC
TGATTTTAACAACCTTAAAG

Product: translation initiation factor IF-5A

Products: NA

Alternate protein names: Hypusine-containing protein; eIF-5A

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MSTKVVEIKTLKVGKYIVLGGEASKITSLTTSSPGKHGAAKARLEAVGIFDNQKRSIVKPVDTKVDIPIIDKRVGQVLSI
QGNNVQLMDMENYDTLDLPMPEELKDQITEGIEVDYIVALGNMKIMRTK

Sequences:

>Translated_129_residues
MSTKVVEIKTLKVGKYIVLGGEASKITSLTTSSPGKHGAAKARLEAVGIFDNQKRSIVKPVDTKVDIPIIDKRVGQVLSI
QGNNVQLMDMENYDTLDLPMPEELKDQITEGIEVDYIVALGNMKIMRTK
>Mature_128_residues
STKVVEIKTLKVGKYIVLGGEASKITSLTTSSPGKHGAAKARLEAVGIFDNQKRSIVKPVDTKVDIPIIDKRVGQVLSIQ
GNNVQLMDMENYDTLDLPMPEELKDQITEGIEVDYIVALGNMKIMRTK

Specific function: Functions by promoting the formation of the first peptide bond

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-5A family

Homologues:

Organism=Caenorhabditis elegans, GI71990399, Length=111, Percent_Identity=32.4324324324324, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF5A_METS3 (A5ULK4)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273450.1
- ProteinModelPortal:   A5ULK4
- SMR:   A5ULK4
- STRING:   A5ULK4
- GeneID:   5217336
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0877
- eggNOG:   arNOG10602
- HOGENOM:   HBG497107
- OMA:   TYETLEL
- ProtClustDB:   PRK03999
- GO:   GO:0005737
- HAMAP:   MF_00085
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR019769
- InterPro:   IPR001884
- InterPro:   IPR022847
- InterPro:   IPR020189
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PANTHER:   PTHR11673
- PIRSF:   PIRSF003025
- TIGRFAMs:   TIGR00037

Pfam domain/function: PF01287 eIF-5a; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 14172; Mature: 14041

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS00302 IF5A_HYPUSINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKVVEIKTLKVGKYIVLGGEASKITSLTTSSPGKHGAAKARLEAVGIFDNQKRSIVKP
CCCEEEEEEEEEECEEEEECCCCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCEECC
VDTKVDIPIIDKRVGQVLSIQGNNVQLMDMENYDTLDLPMPEELKDQITEGIEVDYIVAL
CCCEECCEEECCCCCEEEEECCCCEEEEECCCCCEECCCCCHHHHHHHHCCCCEEEEEEE
GNMKIMRTK
CCEEEEEEC
>Mature Secondary Structure 
STKVVEIKTLKVGKYIVLGGEASKITSLTTSSPGKHGAAKARLEAVGIFDNQKRSIVKP
CCEEEEEEEEEECEEEEECCCCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCEECC
VDTKVDIPIIDKRVGQVLSIQGNNVQLMDMENYDTLDLPMPEELKDQITEGIEVDYIVAL
CCCEECCEEECCCCCEEEEECCCCEEEEECCCCCEECCCCCHHHHHHHHCCCCEEEEEEE
GNMKIMRTK
CCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA