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The map label for this gene is coaD [H]

Identifier: 148642845

GI number: 148642845

Start: 745011

End: 745469

Strand: Reverse

Name: coaD [H]

Synonym: Msm_0785

Alternate gene names: 148642845

Gene position: 745469-745011 (Counterclockwise)

Preceding gene: 148642846

Following gene: 148642844

Centisome position: 40.23

GC content: 32.24

Gene sequence:

>459_bases
ATGGATCATAAAAAATATAAGAAAATAGCTGTTGGGGGAACTTTTGATAAGTTCCATGATGGTCATAAAAAGTTACTTGC
AACTGCTTTTGAATTAGGTGAAGAGGTTGAAATCGGAGTAACTTCTAATGCTTTTGGTGGTCTTAAGGGAGATATTGATT
CCTGTGAAGATAGGATGAGATGTCTTAAGGAATTTTTTAAGGACAGATTAAATTACACTGTTATGGTTTTAGATGATGCA
TATGGGACAACTGTATTCGATGATGAATTTGATGCAATTGTTGTTAGTGAAGAAACTGAACCTGTAGCAGTTGAAATTAA
TGAAATTAGAGATTCTAAAGGAATGTCTCCATTAGATATTGTTGTTGTTAGCTTTGTTTTAGCAGATGATGGTCATCCTA
TTTCGTCTACACGAATTAGGAGTGGTGAAATTAATAAAAAAGGAAATATTTTAAAATAG

Upstream 100 bases:

>100_bases
TTTAATTCTTTTTTATCCATAAAATGATTTTTTTTAATCGCTAATATTTTATAATAGTTTATATAAATTTATATTAGCAA
ACTAATTATAGGACAATATT

Downstream 100 bases:

>100_bases
TATTTTATTATCGAATTAAATCGACATGTTTATATATGCAGTTCGACAATGTATTAATTGATATTAAAATATTATTTTTT
CATAAAATAATTTTCATATC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MDHKKYKKIAVGGTFDKFHDGHKKLLATAFELGEEVEIGVTSNAFGGLKGDIDSCEDRMRCLKEFFKDRLNYTVMVLDDA
YGTTVFDDEFDAIVVSEETEPVAVEINEIRDSKGMSPLDIVVVSFVLADDGHPISSTRIRSGEINKKGNILK

Sequences:

>Translated_152_residues
MDHKKYKKIAVGGTFDKFHDGHKKLLATAFELGEEVEIGVTSNAFGGLKGDIDSCEDRMRCLKEFFKDRLNYTVMVLDDA
YGTTVFDDEFDAIVVSEETEPVAVEINEIRDSKGMSPLDIVVVSFVLADDGHPISSTRIRSGEINKKGNILK
>Mature_152_residues
MDHKKYKKIAVGGTFDKFHDGHKKLLATAFELGEEVEIGVTSNAFGGLKGDIDSCEDRMRCLKEFFKDRLNYTVMVLDDA
YGTTVFDDEFDAIVVSEETEPVAVEINEIRDSKGMSPLDIVVVSFVLADDGHPISSTRIRSGEINKKGNILK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG1019

COG function: function code R; Predicted nucleotidyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic CoaD family [H]

Homologues:

Organism=Caenorhabditis elegans, GI25143409, Length=154, Percent_Identity=33.1168831168831, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321716, Length=150, Percent_Identity=35.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24658602, Length=145, Percent_Identity=34.4827586206897, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 16892; Mature: 16892

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHKKYKKIAVGGTFDKFHDGHKKLLATAFELGEEVEIGVTSNAFGGLKGDIDSCEDRMR
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHH
CLKEFFKDRLNYTVMVLDDAYGTTVFDDEFDAIVVSEETEPVAVEINEIRDSKGMSPLDI
HHHHHHHHHCCEEEEEEECCCCCEEECCCCCEEEEECCCCCEEEEEEEHHCCCCCCHHHH
VVVSFVLADDGHPISSTRIRSGEINKKGNILK
HHHHHHHCCCCCCCCCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MDHKKYKKIAVGGTFDKFHDGHKKLLATAFELGEEVEIGVTSNAFGGLKGDIDSCEDRMR
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHH
CLKEFFKDRLNYTVMVLDDAYGTTVFDDEFDAIVVSEETEPVAVEINEIRDSKGMSPLDI
HHHHHHHHHCCEEEEEEECCCCCEEECCCCCEEEEECCCCCEEEEEEEHHCCCCCCHHHH
VVVSFVLADDGHPISSTRIRSGEINKKGNILK
HHHHHHHCCCCCCCCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]