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The map label for this gene is sucD [H]

Identifier: 148642288

GI number: 148642288

Start: 216959

End: 217819

Strand: Reverse

Name: sucD [H]

Synonym: Msm_0228

Alternate gene names: 148642288

Gene position: 217819-216959 (Counterclockwise)

Preceding gene: 148642289

Following gene: 148642287

Centisome position: 11.75

GC content: 36.0

Gene sequence:

>861_bases
ATGATTTTATTAGATAATGATACAAAATGTTTGGTTCAGGGGATTACCGGAAAACAGGGATCTTTTCACACCGAACAAAT
GTTGGAATATAATACAAATATTTTGGCAGGTGTAACTCCTGGAAAAGGGGGTCAAGACTTTTTAGGTGTTCCTGTTTTCA
ATTCAATTGAAGAAGCAAAAGAGGAAACTGGCGTTAACTCTTCAATTATTTTTGTACCTGCAAAATTTGCAAAAGATGCG
GCATTTGAATCTATAAGACATTTGGATTTGGTTGTTATTATTTCAGAACATATTCCTGTTCATGACAGTTTAAAAATAAT
GAATTATGCTCGTGAAATGGACACTACAGTTATAGGTCCAAACACTCCTGGAATTATAACTCCTGGTGTTGGTAAACTGG
GAATTATGCCGACTCATATTTTTGAAGAAGGTAATGTCGGAGTAATTTCAAGAAGCGGAACTTTAACATACGAAGTAGCC
AGCCAGCTTACCCGTGGAGGAATTGGTCAAAGTACATGTGTAGGTATAGGTGGAGACCCTGTAATCGGTACAAATTATAT
TGATATTCTTAAAAAATTTGAAGAAGATGATGACACTGAAGCTATTGTTTTAATTGGTGAAATTGGAGGTAATGCTGAAG
AAAATGCAGCAGAATTTATTAAAGACAATATCTCCAAACCGGTAGTTTCATATATCGCAGGTAGGACCGCACCACCTGGT
AAAAGAATGGGGCATGCAGGAGCTATTATTCATGGAAGTTCAGGTACTGCAGAAAGTAAAATTAATGCATTAACTGATGC
CGGTGTAAGTGTAGCTAAAATGCCATCAGAAATTGTAGATTTAGTAAGGAAGTCAATTTAA

Upstream 100 bases:

>100_bases
TATATTTTCTGCTACAGCTTTTATGAATGGAAATGTAATTGATTTGGCAGTTCCATTTGAAAACAAAACAAGAATTTTAC
GTTAAAAAGGTGGTTGTTTT

Downstream 100 bases:

>100_bases
ATGAATTCTAAAGAAATTATTGATAAATTGTTAAATGGTGAAATGAAATTATACCAGGTAGACAAATATGTTTCACCAAA
AGAGGCTACAGATATTAGAA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MILLDNDTKCLVQGITGKQGSFHTEQMLEYNTNILAGVTPGKGGQDFLGVPVFNSIEEAKEETGVNSSIIFVPAKFAKDA
AFESIRHLDLVVIISEHIPVHDSLKIMNYAREMDTTVIGPNTPGIITPGVGKLGIMPTHIFEEGNVGVISRSGTLTYEVA
SQLTRGGIGQSTCVGIGGDPVIGTNYIDILKKFEEDDDTEAIVLIGEIGGNAEENAAEFIKDNISKPVVSYIAGRTAPPG
KRMGHAGAIIHGSSGTAESKINALTDAGVSVAKMPSEIVDLVRKSI

Sequences:

>Translated_286_residues
MILLDNDTKCLVQGITGKQGSFHTEQMLEYNTNILAGVTPGKGGQDFLGVPVFNSIEEAKEETGVNSSIIFVPAKFAKDA
AFESIRHLDLVVIISEHIPVHDSLKIMNYAREMDTTVIGPNTPGIITPGVGKLGIMPTHIFEEGNVGVISRSGTLTYEVA
SQLTRGGIGQSTCVGIGGDPVIGTNYIDILKKFEEDDDTEAIVLIGEIGGNAEENAAEFIKDNISKPVVSYIAGRTAPPG
KRMGHAGAIIHGSSGTAESKINALTDAGVSVAKMPSEIVDLVRKSI
>Mature_286_residues
MILLDNDTKCLVQGITGKQGSFHTEQMLEYNTNILAGVTPGKGGQDFLGVPVFNSIEEAKEETGVNSSIIFVPAKFAKDA
AFESIRHLDLVVIISEHIPVHDSLKIMNYAREMDTTVIGPNTPGIITPGVGKLGIMPTHIFEEGNVGVISRSGTLTYEVA
SQLTRGGIGQSTCVGIGGDPVIGTNYIDILKKFEEDDDTEAIVLIGEIGGNAEENAAEFIKDNISKPVVSYIAGRTAPPG
KRMGHAGAIIHGSSGTAESKINALTDAGVSVAKMPSEIVDLVRKSI

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=289, Percent_Identity=55.363321799308, Blast_Score=268, Evalue=3e-72,
Organism=Homo sapiens, GI38569421, Length=307, Percent_Identity=28.9902280130293, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI38569423, Length=307, Percent_Identity=28.9902280130293, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1786949, Length=283, Percent_Identity=55.1236749116608, Blast_Score=312, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17553126, Length=291, Percent_Identity=51.8900343642612, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17550194, Length=283, Percent_Identity=53.0035335689046, Blast_Score=276, Evalue=9e-75,
Organism=Caenorhabditis elegans, GI17557344, Length=309, Percent_Identity=27.1844660194175, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17551266, Length=310, Percent_Identity=26.4516129032258, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324716, Length=284, Percent_Identity=50, Blast_Score=253, Evalue=3e-68,
Organism=Drosophila melanogaster, GI21356559, Length=283, Percent_Identity=49.469964664311, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI28574296, Length=281, Percent_Identity=49.1103202846975, Blast_Score=248, Evalue=3e-66,
Organism=Drosophila melanogaster, GI281363477, Length=299, Percent_Identity=27.0903010033445, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281363475, Length=299, Percent_Identity=27.0903010033445, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281363473, Length=299, Percent_Identity=27.0903010033445, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30203; Mature: 30203

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLDNDTKCLVQGITGKQGSFHTEQMLEYNTNILAGVTPGKGGQDFLGVPVFNSIEEAK
CEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
EETGVNSSIIFVPAKFAKDAAFESIRHLDLVVIISEHIPVHDSLKIMNYAREMDTTVIGP
HHHCCCCEEEEEEHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHCCEEECC
NTPGIITPGVGKLGIMPTHIFEEGNVGVISRSGTLTYEVASQLTRGGIGQSTCVGIGGDP
CCCCEECCCCCCCCCCCHHEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCCCC
VIGTNYIDILKKFEEDDDTEAIVLIGEIGGNAEENAAEFIKDNISKPVVSYIAGRTAPPG
CCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCC
KRMGHAGAIIHGSSGTAESKINALTDAGVSVAKMPSEIVDLVRKSI
CCCCCCCEEEECCCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MILLDNDTKCLVQGITGKQGSFHTEQMLEYNTNILAGVTPGKGGQDFLGVPVFNSIEEAK
CEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
EETGVNSSIIFVPAKFAKDAAFESIRHLDLVVIISEHIPVHDSLKIMNYAREMDTTVIGP
HHHCCCCEEEEEEHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHCCEEECC
NTPGIITPGVGKLGIMPTHIFEEGNVGVISRSGTLTYEVASQLTRGGIGQSTCVGIGGDP
CCCCEECCCCCCCCCCCHHEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCCCC
VIGTNYIDILKKFEEDDDTEAIVLIGEIGGNAEENAAEFIKDNISKPVVSYIAGRTAPPG
CCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCC
KRMGHAGAIIHGSSGTAESKINALTDAGVSVAKMPSEIVDLVRKSI
CCCCCCCEEEECCCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]