Click here to switch to the map view.

The map label for this gene is 148642184

Identifier: 148642184

GI number: 148642184

Start: 122496

End: 123248

Strand: Reverse

Name: 148642184

Synonym: Msm_0124

Alternate gene names: NA

Gene position: 123248-122496 (Counterclockwise)

Preceding gene: 148642185

Following gene: 148642183

Centisome position: 6.65

GC content: 35.86

Gene sequence:

>753_bases
ATGGAAATGGTCGAAGAACATATTAAAGGTATATTAAAAAATAGGAAAATTCATTTTACTTTAATTGATCCTGATGAACA
AACACCACAGGAAGCTTTAGAAATAGCTGAAGAAGCTATTCTTGGTGGAACTGACGGAATTATGATTGGAGGGTCAACTG
TTAATAATGATGAAGTTGATGAAACTTGTAAAATATTATCTGAGAATATAGAAGTTCCAATTATTTTATTCCCTGGAAAT
ATTAATAGTGTAAGTAAATATGCAGATGCAATTTTCTTTATGAGCTATTTAAATTCTACCAATCCTTATTGGATTTATGG
TGCTCAGGCATTAGCTGCACCAATTGTAAGGCAAGCTGGAATTGAAGTTTTACCAATGGGCTATATGGTTGTTCAGCCTG
GAGGAACTGTTGGATGGGTGGGAGATGCCAAATTAGTACCTAGAAACAAACCAAAAATACCTGCAGCTTATGCGATGTCT
GCTGAACTTTTAGGAATGAGATTTTTCTACATTGAAGCAGGTTCCGGAGCAGATAAACCGATTCCACCAGAAATGGTAGG
ATATACTAAAAAAGCTACTGAAGATATGGTAATTATTGTTGGTGGAGGTATCCGTGATGGTGAAGCTGCATATACAGCAG
CAAAAGCTGGCGGGGATATAATTGTTACCGGAACAGTTGTAGAAGAAACCAATGATGTTAGGGGTAAAATTGAAGAAATT
ACAGCAGCTATTAGAAAAGCTTCAATAGAATAG

Upstream 100 bases:

>100_bases
TCATTGTTTTTACATTAAATTTAAGAGTTCTATAAACATTAATTTAATATAATATTGTTTACACAAATAACTGTATTAAG
ATATTTATATAGGGATTTTT

Downstream 100 bases:

>100_bases
TTTTCAAATACTCTTAGCTAATTTTTTTATTATTTAACTAACTTATTTTTTATTAGAGATTATGTTAAATTCATTGTATA
TTAAAGCAGCCAGTAAAAGG

Product: geranylgeranylglyceryl phosphate synthase-like protein

Products: NA

Alternate protein names: GGGP synthase; GGGPS; (S)-3-O-geranylgeranylglyceryl phosphate synthase; Phosphoglycerol geranylgeranyltransferase

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MEMVEEHIKGILKNRKIHFTLIDPDEQTPQEALEIAEEAILGGTDGIMIGGSTVNNDEVDETCKILSENIEVPIILFPGN
INSVSKYADAIFFMSYLNSTNPYWIYGAQALAAPIVRQAGIEVLPMGYMVVQPGGTVGWVGDAKLVPRNKPKIPAAYAMS
AELLGMRFFYIEAGSGADKPIPPEMVGYTKKATEDMVIIVGGGIRDGEAAYTAAKAGGDIIVTGTVVEETNDVRGKIEEI
TAAIRKASIE

Sequences:

>Translated_250_residues
MEMVEEHIKGILKNRKIHFTLIDPDEQTPQEALEIAEEAILGGTDGIMIGGSTVNNDEVDETCKILSENIEVPIILFPGN
INSVSKYADAIFFMSYLNSTNPYWIYGAQALAAPIVRQAGIEVLPMGYMVVQPGGTVGWVGDAKLVPRNKPKIPAAYAMS
AELLGMRFFYIEAGSGADKPIPPEMVGYTKKATEDMVIIVGGGIRDGEAAYTAAKAGGDIIVTGTVVEETNDVRGKIEEI
TAAIRKASIE
>Mature_250_residues
MEMVEEHIKGILKNRKIHFTLIDPDEQTPQEALEIAEEAILGGTDGIMIGGSTVNNDEVDETCKILSENIEVPIILFPGN
INSVSKYADAIFFMSYLNSTNPYWIYGAQALAAPIVRQAGIEVLPMGYMVVQPGGTVGWVGDAKLVPRNKPKIPAAYAMS
AELLGMRFFYIEAGSGADKPIPPEMVGYTKKATEDMVIIVGGGIRDGEAAYTAAKAGGDIIVTGTVVEETNDVRGKIEEI
TAAIRKASIE

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membr

COG id: COG1646

COG function: function code R; Predicted phosphate-binding enzymes, TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GGGP synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGGPS_METS3 (A5UJF1)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001272697.1
- ProteinModelPortal:   A5UJF1
- SMR:   A5UJF1
- STRING:   A5UJF1
- GeneID:   5216790
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0124
- eggNOG:   arNOG05493
- HOGENOM:   HBG313841
- OMA:   ADAIFFM
- ProtClustDB:   PRK04169
- GO:   GO:0005737
- HAMAP:   MF_00112
- InterPro:   IPR008205
- InterPro:   IPR010946
- Gene3D:   G3DSA:3.20.20.390
- TIGRFAMs:   TIGR01769
- TIGRFAMs:   TIGR01768

Pfam domain/function: PF01884 PcrB

EC number: =2.5.1.41

Molecular weight: Translated: 26865; Mature: 26865

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: BINDING 203-203

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMVEEHIKGILKNRKIHFTLIDPDEQTPQEALEIAEEAILGGTDGIMIGGSTVNNDEVD
CCHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHH
ETCKILSENIEVPIILFPGNINSVSKYADAIFFMSYLNSTNPYWIYGAQALAAPIVRQAG
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCC
IEVLPMGYMVVQPGGTVGWVGDAKLVPRNKPKIPAAYAMSAELLGMRFFYIEAGSGADKP
CEEEECCEEEECCCCCEEECCCCEECCCCCCCCCHHHHHHHHHHCEEEEEEECCCCCCCC
IPPEMVGYTKKATEDMVIIVGGGIRDGEAAYTAAKAGGDIIVTGTVVEETNDVRGKIEEI
CCHHHHCCCCCCCCCEEEEEECCCCCCCHHEEHHCCCCCEEEEEEEEECCCHHHHHHHHH
TAAIRKASIE
HHHHHHHCCC
>Mature Secondary Structure
MEMVEEHIKGILKNRKIHFTLIDPDEQTPQEALEIAEEAILGGTDGIMIGGSTVNNDEVD
CCHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHH
ETCKILSENIEVPIILFPGNINSVSKYADAIFFMSYLNSTNPYWIYGAQALAAPIVRQAG
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCC
IEVLPMGYMVVQPGGTVGWVGDAKLVPRNKPKIPAAYAMSAELLGMRFFYIEAGSGADKP
CEEEECCEEEECCCCCEEECCCCEECCCCCCCCCHHHHHHHHHHCEEEEEEECCCCCCCC
IPPEMVGYTKKATEDMVIIVGGGIRDGEAAYTAAKAGGDIIVTGTVVEETNDVRGKIEEI
CCHHHHCCCCCCCCCEEEEEECCCCCCCHHEEHHCCCCCEEEEEEEEECCCHHHHHHHHH
TAAIRKASIE
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA