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The map label for this gene is accD

Identifier: 148381533

GI number: 148381533

Start: 3838881

End: 3839750

Strand: Reverse

Name: accD

Synonym: CBO3595

Alternate gene names: 148381533

Gene position: 3839750-3838881 (Counterclockwise)

Preceding gene: 148381534

Following gene: 148381532

Centisome position: 98.79

GC content: 28.85

Gene sequence:

>870_bases
ATGTTAAAAAATTTATTTAGAAAAACAAAGTATATAACTGTAAGTCAAAAGAATATAGAAAATTATAAAAGAGAAAATAC
TCCTACTATTCCAGATGGAATGTGGGTTAAATGTAATAAATGTGGAGAGATATTATACCAAAATGATTTAGAAAAGAATT
ATATGGTATGTAATTTATGTGGAAATCATTTTAGAATAGGTGTTAAAGAAAGAATAAAATATTTATTCGATAAAGATACC
TTTAAAGAATGGGATTATAAAATTAAAACAGAAAATCCATTAGATTTTAAAGGCTATGATGAAAAAATAGAACATATAAA
AGAAAAAACAAACTTAAGTGAAGCTGTTACAACAGGTAAATGTAAAATAGCTGGTATGGAAGTTGTAGTATGTATAATGG
ATAGTAAATTCATGATGGGAAGTATGGGATCTGTTGTAGGAGAAAAAATAACTAGAGCTATAGAAAGAGCTATAGGGTTA
AGATTGCCAGTTATAATATTTACTGCATCTGGTGGGGCAAGAATGCAGGAAGGAATATTATCTTTAATGCAAATGGCTAA
AGTAAGTTCTGCATTAGCAAAATTAGATGAAGAAGGATTATTATATATATGTGTACTAACAGATCCAACTACAGGAGGGG
TCACAGCTAGTTTTGCTATGCTTGGAGATATAATACTTGCTGAACCAGATGCGTTAATAGGATTTGCAGGTAAGAGGGTA
ATAGAACAAACCATAAATGAAAAGTTACCAGAGGACTTTCAGAAATCTGAATTTTTGTTAGAGCATGGTTTTATTGATAA
AATAGTCCCAAGGTCTGATTTAAGAAAAGTTTTAGCAAAGCTTATTAATATGCATCAAAATTCTTTTTAA

Upstream 100 bases:

>100_bases
TTTATTATATTAGAGGATGAAAATTTTATAAAGGGAGAATACACTACAAAATATATAGAAAAAATGCTAACTGACAATTA
GTGTAGTCAGGGGGAAGTAT

Downstream 100 bases:

>100_bases
AACTATACATTAATATTATTTCTTAATTTAGATTGGAGATATAAATATGGAAGATAAAAAATTGATTCATAATGTAAAAA
AATATGCTTCTAAAAATGCT

Product: acetyl-CoA carboxylase carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MLKNLFRKTKYITVSQKNIENYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLCGNHFRIGVKERIKYLFDKDT
FKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGKCKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIGL
RLPVIIFTASGGARMQEGILSLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRV
IEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF

Sequences:

>Translated_289_residues
MLKNLFRKTKYITVSQKNIENYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLCGNHFRIGVKERIKYLFDKDT
FKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGKCKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIGL
RLPVIIFTASGGARMQEGILSLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRV
IEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF
>Mature_289_residues
MLKNLFRKTKYITVSQKNIENYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLCGNHFRIGVKERIKYLFDKDT
FKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGKCKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIGL
RLPVIIFTASGGARMQEGILSLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRV
IEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=277, Percent_Identity=49.8194945848375, Blast_Score=272, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI25147359, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25147362, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_CLOB1 (A7FPN5)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385907.1
- ProteinModelPortal:   A7FPN5
- SMR:   A7FPN5
- STRING:   A7FPN5
- GeneID:   5396955
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3675
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   CLSK883536
- BioCyc:   CBOT441770:CLB_3675-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32700; Mature: 32700

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNLFRKTKYITVSQKNIENYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLC
CCHHHHHHHHEEEEEHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEEC
GNHFRIGVKERIKYLFDKDTFKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGK
CCCEEECHHHHHHHHHCCCCHHCCCEEECCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCC
CKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIGLRLPVIIFTASGGARMQEGIL
EEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
SLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRV
HHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHEECCCHHHHHHHHHH
IEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF
HHHHHHHHCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKNLFRKTKYITVSQKNIENYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLC
CCHHHHHHHHEEEEEHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEEC
GNHFRIGVKERIKYLFDKDTFKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGK
CCCEEECHHHHHHHHHCCCCHHCCCEEECCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCC
CKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIGLRLPVIIFTASGGARMQEGIL
EEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
SLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRV
HHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHEECCCHHHHHHHHHH
IEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF
HHHHHHHHCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA