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The map label for this gene is fumA [C]

Identifier: 148381382

GI number: 148381382

Start: 3683845

End: 3684687

Strand: Reverse

Name: fumA [C]

Synonym: CBO3442

Alternate gene names: 148381382

Gene position: 3684687-3683845 (Counterclockwise)

Preceding gene: 148381383

Following gene: 148381381

Centisome position: 94.8

GC content: 32.27

Gene sequence:

>843_bases
ATGAGGGAAATATCAGTAAATACTATAAAAAAAGTAGTGAAAAAATTATGCATAGAAGCTAATTATTATTTGCCTAAAGA
TGTAGATGACAAAATAGTACAATGTAGGGAAGTAGAAACTTGGAACATAGCTAGAGAGGTTTTACAAACTATAGAAGAAA
ATATACATATAGCTAGAAAAGAGAATATACCCTTATGTCAGGATACAGGTATGGCATGTATATTTATTGAAATGGGTCAA
GATGTTCATGTAATTGGAGGATTTCTAGAAGATGCTGTTAATGAAGGTGTAGCAGAAGGATACAATGAAGGATATTTAAG
AAAATCTATAGTTAGTGACCCTATAGAAAGAATAAATACAGGAGATAATACCCCAGCAGTAATATATTATAATATAGTTC
AAGGGGATAAAATTAAGATAACCGTAGCTCCAAAGGGGTTTGGATCAGAAAACATGAGTAAGATAGCTATGTTAAAGCCA
GCAGATGGGTTAGAAGGTATAAAAAATTTTATTTTAGATGTAGTTAAAGAAGCAGGGCCTAATCCGTGTCCACCTATAGT
TATAGGAGTTGGTATAGGAGGAACTTTTGATAAATGTGCTTATTTGTCTAAAAAGGCACTTTTAAGATCAATAGATTTGA
GAAATAAAAATAAATTTTATAAAGATTTAGAGGAAGAATTACTAGAAAAAATTAATAGCTTAGGCATAGGGCCTCAAGGC
TTTGGTGGGAAAACTACAGCGTTGGCGGTTAATATAGAAACCTTCCCAACTCACATAGCAGGTTTACCAGTAGCAGTAAA
TGTAAGTTGCCATGTTACTAGGCATAAAGAGGAAATAATATAA

Upstream 100 bases:

>100_bases
TTTTATAAAGACCGATGTAGATTGATGTAGAAAAAAACATGTAATTAAACTATAATATTCATAAGTATGTGTTTTAAAAT
ATTGTATTTTGGAGGATAAA

Downstream 100 bases:

>100_bases
AAATTATAGTTTATATTATTTATATATTCTATGTGTAAAATAAATAAATATAACCTCCTTTAATATATTCTAAAGGAGAT
ATAAAGAGCAGGTGATTTTA

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MREISVNTIKKVVKKLCIEANYYLPKDVDDKIVQCREVETWNIAREVLQTIEENIHIARKENIPLCQDTGMACIFIEMGQ
DVHVIGGFLEDAVNEGVAEGYNEGYLRKSIVSDPIERINTGDNTPAVIYYNIVQGDKIKITVAPKGFGSENMSKIAMLKP
ADGLEGIKNFILDVVKEAGPNPCPPIVIGVGIGGTFDKCAYLSKKALLRSIDLRNKNKFYKDLEEELLEKINSLGIGPQG
FGGKTTALAVNIETFPTHIAGLPVAVNVSCHVTRHKEEII

Sequences:

>Translated_280_residues
MREISVNTIKKVVKKLCIEANYYLPKDVDDKIVQCREVETWNIAREVLQTIEENIHIARKENIPLCQDTGMACIFIEMGQ
DVHVIGGFLEDAVNEGVAEGYNEGYLRKSIVSDPIERINTGDNTPAVIYYNIVQGDKIKITVAPKGFGSENMSKIAMLKP
ADGLEGIKNFILDVVKEAGPNPCPPIVIGVGIGGTFDKCAYLSKKALLRSIDLRNKNKFYKDLEEELLEKINSLGIGPQG
FGGKTTALAVNIETFPTHIAGLPVAVNVSCHVTRHKEEII
>Mature_280_residues
MREISVNTIKKVVKKLCIEANYYLPKDVDDKIVQCREVETWNIAREVLQTIEENIHIARKENIPLCQDTGMACIFIEMGQ
DVHVIGGFLEDAVNEGVAEGYNEGYLRKSIVSDPIERINTGDNTPAVIYYNIVQGDKIKITVAPKGFGSENMSKIAMLKP
ADGLEGIKNFILDVVKEAGPNPCPPIVIGVGIGGTFDKCAYLSKKALLRSIDLRNKNKFYKDLEEELLEKINSLGIGPQG
FGGKTTALAVNIETFPTHIAGLPVAVNVSCHVTRHKEEII

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=277, Percent_Identity=32.129963898917, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1790564, Length=244, Percent_Identity=34.8360655737705, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787897, Length=245, Percent_Identity=34.6938775510204, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30854; Mature: 30854

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREISVNTIKKVVKKLCIEANYYLPKDVDDKIVQCREVETWNIAREVLQTIEENIHIARK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEC
ENIPLCQDTGMACIFIEMGQDVHVIGGFLEDAVNEGVAEGYNEGYLRKSIVSDPIERINT
CCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
GDNTPAVIYYNIVQGDKIKITVAPKGFGSENMSKIAMLKPADGLEGIKNFILDVVKEAGP
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
NPCPPIVIGVGIGGTFDKCAYLSKKALLRSIDLRNKNKFYKDLEEELLEKINSLGIGPQG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
FGGKTTALAVNIETFPTHIAGLPVAVNVSCHVTRHKEEII
CCCCEEEEEEEEECCCHHHCCCCEEEEEEEEEECCHHHCC
>Mature Secondary Structure
MREISVNTIKKVVKKLCIEANYYLPKDVDDKIVQCREVETWNIAREVLQTIEENIHIARK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEC
ENIPLCQDTGMACIFIEMGQDVHVIGGFLEDAVNEGVAEGYNEGYLRKSIVSDPIERINT
CCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
GDNTPAVIYYNIVQGDKIKITVAPKGFGSENMSKIAMLKPADGLEGIKNFILDVVKEAGP
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
NPCPPIVIGVGIGGTFDKCAYLSKKALLRSIDLRNKNKFYKDLEEELLEKINSLGIGPQG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
FGGKTTALAVNIETFPTHIAGLPVAVNVSCHVTRHKEEII
CCCCEEEEEEEEECCCHHHCCCCEEEEEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]