| Definition | Clostridium botulinum A str. ATCC 3502, complete genome. |
|---|---|
| Accession | NC_009495 |
| Length | 3,886,916 |
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The map label for this gene is ctpA [H]
Identifier: 148381329
GI number: 148381329
Start: 3630418
End: 3631623
Strand: Reverse
Name: ctpA [H]
Synonym: CBO3389
Alternate gene names: 148381329
Gene position: 3631623-3630418 (Counterclockwise)
Preceding gene: 148381330
Following gene: 148381328
Centisome position: 93.43
GC content: 28.03
Gene sequence:
>1206_bases TTGAAAAAAAATAAAAAATGGATTATATGGACAGTAGTTATAGTATTAGTAACAAATATTTTTACATTTTTAGGTACAAA TTTGGTTTCTTTATATTTGCCTAATGGCAAAGTTATAATTGGAGCAGACCAATATAAAGATATATTAAAATATCAAAAGA TGTTTTTAATAAGAAATCAAATATATAAGTATTACGATGGTAAAATAGATGAAAGTAAGATGGTAGAAGGTGCAGTAAAA GGAATGACAGAATCTTTAAATGACCCTTATACTGTATTTATGAATGCTAAAGAGTACAAAGAATTTAATGCTCAAACAGA AGGTAATTATAGTGGGGTAGGAATACAAATACAAGCTAAAGATGATAAAATAATTGTAGCTTCTACTTTTGAAGGATCTC CGGCTAAAGAGGCAGGAATACTACCAAAGGATGAAATTCAAAAAGTTAATAATACAACAGTATCAGGAAAAGAGTTGGAA AAGGCTGTTTCCATAATGAAGGGAAAAGAAGGCACAGATGTTAAGTTACAATTATATAGAAAAGAAAAAGGAAGTTTTGA AGTAACACTAAAGAGAAAAAAGATAGATATACCTACTATAAAATCAGAAATGATTGATAATAATATAGGATATATACAAG TAAGTATGTTTGATGAAAATACTTCAAAAAACTTTAAAAATGCTTTAAATGATTTAAAAGATAAGGGTATGAAATCTTTA TTATTAGATTTGAGAGGAAATCCAGGAGGGCTATTAGATGAATGTATTAATATGGCTTCTAATTTTATAGAAAAGGGAAA GGTTGTAGTATCAACTATAGATAAATATGGAAGCAAAAAAGAATATAAATCTAAAGGTGGAGATTTTATAGGATTTCCAG TAACTATATTAGTAGATGAAGGTTCTGCAAGTGCTTCGGAGGTATTTTTAGGAGCCATGAAAGACTATAATGTAGCCACA TCTATAGGAAAGAAAACTTTTGGAAAGGGTGTAGTTCAAACTATAATAGAGACTGGTGATAATACGGCCCTTAAAGTTAC GATTTCAAAATATTATTCACCTAAAGGTGTAAACATAAATCATAAAGGAATAACTCCAGATATGGAAATAGATTATCCAG AGGAGTTAAGAAAGAAAGAATATGATAGAAAAGTAGATCCTCAATTTAATAAAGCTTTAAATATTGCAAAATCAAAGATA AGATAA
Upstream 100 bases:
>100_bases TTTAAAATTAATTTTTTATTTTCTGTAATAATGTATTATTTAATATATAATACTTATATATTACTAATATATATTAAGGC TAAACAAAGAGGTGGGTAAT
Downstream 100 bases:
>100_bases TATTGTATTTGATCTTTATATTTTTATATAGATGGTTTAGTTAGACTTTCTAACTAAACCATAGTTATGGAGAGGGGAAT TTTTTTTAATGGACATATTA
Product: carboxyl-terminal protease
Products: NA
Alternate protein names: C-terminal processing protease [H]
Number of amino acids: Translated: 401; Mature: 401
Protein sequence:
>401_residues MKKNKKWIIWTVVIVLVTNIFTFLGTNLVSLYLPNGKVIIGADQYKDILKYQKMFLIRNQIYKYYDGKIDESKMVEGAVK GMTESLNDPYTVFMNAKEYKEFNAQTEGNYSGVGIQIQAKDDKIIVASTFEGSPAKEAGILPKDEIQKVNNTTVSGKELE KAVSIMKGKEGTDVKLQLYRKEKGSFEVTLKRKKIDIPTIKSEMIDNNIGYIQVSMFDENTSKNFKNALNDLKDKGMKSL LLDLRGNPGGLLDECINMASNFIEKGKVVVSTIDKYGSKKEYKSKGGDFIGFPVTILVDEGSASASEVFLGAMKDYNVAT SIGKKTFGKGVVQTIIETGDNTALKVTISKYYSPKGVNINHKGITPDMEIDYPEELRKKEYDRKVDPQFNKALNIAKSKI R
Sequences:
>Translated_401_residues MKKNKKWIIWTVVIVLVTNIFTFLGTNLVSLYLPNGKVIIGADQYKDILKYQKMFLIRNQIYKYYDGKIDESKMVEGAVK GMTESLNDPYTVFMNAKEYKEFNAQTEGNYSGVGIQIQAKDDKIIVASTFEGSPAKEAGILPKDEIQKVNNTTVSGKELE KAVSIMKGKEGTDVKLQLYRKEKGSFEVTLKRKKIDIPTIKSEMIDNNIGYIQVSMFDENTSKNFKNALNDLKDKGMKSL LLDLRGNPGGLLDECINMASNFIEKGKVVVSTIDKYGSKKEYKSKGGDFIGFPVTILVDEGSASASEVFLGAMKDYNVAT SIGKKTFGKGVVQTIIETGDNTALKVTISKYYSPKGVNINHKGITPDMEIDYPEELRKKEYDRKVDPQFNKALNIAKSKI R >Mature_401_residues MKKNKKWIIWTVVIVLVTNIFTFLGTNLVSLYLPNGKVIIGADQYKDILKYQKMFLIRNQIYKYYDGKIDESKMVEGAVK GMTESLNDPYTVFMNAKEYKEFNAQTEGNYSGVGIQIQAKDDKIIVASTFEGSPAKEAGILPKDEIQKVNNTTVSGKELE KAVSIMKGKEGTDVKLQLYRKEKGSFEVTLKRKKIDIPTIKSEMIDNNIGYIQVSMFDENTSKNFKNALNDLKDKGMKSL LLDLRGNPGGLLDECINMASNFIEKGKVVVSTIDKYGSKKEYKSKGGDFIGFPVTILVDEGSASASEVFLGAMKDYNVAT SIGKKTFGKGVVQTIIETGDNTALKVTISKYYSPKGVNINHKGITPDMEIDYPEELRKKEYDRKVDPQFNKALNIAKSKI R
Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]
COG id: COG0793
COG function: function code M; Periplasmic protease
Gene ontology:
Cell location: Associated With The Periplasmic Protein Side Of The Cytoplasm Membrane [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PDZ (DHR) domain [H]
Homologues:
Organism=Escherichia coli, GI1788134, Length=306, Percent_Identity=30.3921568627451, Blast_Score=131, Evalue=9e-32,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001478 - InterPro: IPR005151 - InterPro: IPR004447 - InterPro: IPR002477 [H]
Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]
EC number: =3.4.21.102 [H]
Molecular weight: Translated: 44881; Mature: 44881
Theoretical pI: Translated: 9.75; Mature: 9.75
Prosite motif: PS50106 PDZ
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKNKKWIIWTVVIVLVTNIFTFLGTNLVSLYLPNGKVIIGADQYKDILKYQKMFLIRNQ CCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHH IYKYYDGKIDESKMVEGAVKGMTESLNDPYTVFMNAKEYKEFNAQTEGNYSGVGIQIQAK HHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCCCCCEEEEEEEC DDKIIVASTFEGSPAKEAGILPKDEIQKVNNTTVSGKELEKAVSIMKGKEGTDVKLQLYR CCEEEEEEECCCCCCHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEE KEKGSFEVTLKRKKIDIPTIKSEMIDNNIGYIQVSMFDENTSKNFKNALNDLKDKGMKSL CCCCCEEEEEEEEECCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH LLDLRGNPGGLLDECINMASNFIEKGKVVVSTIDKYGSKKEYKSKGGDFIGFPVTILVDE HHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCHHHHHCCCCEEECEEEEEEEC GSASASEVFLGAMKDYNVATSIGKKTFGKGVVQTIIETGDNTALKVTISKYYSPKGVNIN CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC HKGITPDMEIDYPEELRKKEYDRKVDPQFNKALNIAKSKIR CCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCC >Mature Secondary Structure MKKNKKWIIWTVVIVLVTNIFTFLGTNLVSLYLPNGKVIIGADQYKDILKYQKMFLIRNQ CCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHH IYKYYDGKIDESKMVEGAVKGMTESLNDPYTVFMNAKEYKEFNAQTEGNYSGVGIQIQAK HHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCCCCCEEEEEEEC DDKIIVASTFEGSPAKEAGILPKDEIQKVNNTTVSGKELEKAVSIMKGKEGTDVKLQLYR CCEEEEEEECCCCCCHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEE KEKGSFEVTLKRKKIDIPTIKSEMIDNNIGYIQVSMFDENTSKNFKNALNDLKDKGMKSL CCCCCEEEEEEEEECCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH LLDLRGNPGGLLDECINMASNFIEKGKVVVSTIDKYGSKKEYKSKGGDFIGFPVTILVDE HHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCHHHHHCCCCEEECEEEEEEEC GSASASEVFLGAMKDYNVATSIGKKTFGKGVVQTIIETGDNTALKVTISKYYSPKGVNIN CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC HKGITPDMEIDYPEELRKKEYDRKVDPQFNKALNIAKSKIR CCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8996100; 9734814; 9384377 [H]