Click here to switch to the map view.

The map label for this gene is patA [H]

Identifier: 148381103

GI number: 148381103

Start: 3357272

End: 3358441

Strand: Reverse

Name: patA [H]

Synonym: CBO3154

Alternate gene names: 148381103

Gene position: 3358441-3357272 (Counterclockwise)

Preceding gene: 148381105

Following gene: 148381099

Centisome position: 86.4

GC content: 28.46

Gene sequence:

>1170_bases
ATGGATTATATAAAGACTGAAGAAATTATTTCGGAAAAAGTTAAAAATATAGAAATTTCCGGTATAAGGAGGTTTTTTAA
CAAAGTTTCAAATTATAAAGATGTTATTTCCTTAACTTTAGGGCAACCAGACTTTAAGCTTCCAAGTAGAATAAAAGATG
AATTAATAAATTCTATACAAGAAGATAAAACAACCTATACATCTAATGCAGGACTAAAAGAGTTAAGATTAGAGATAGCA
AGATATCTTAAAACTATGAATATTAATTATAATTCAGAAGAAATATGCATAACCGTAGGTGGTAGTGAAGGGTTGATGTG
TGTATTTTCCACATTACTAAATGAGGGAGACAAAGTTTTAATACCAACACCTGCATATCCTGCTTATGAAAGCTGTGTAA
AATTATTAGGTGGACAAATATTAAATTATAAATTAAAAAATGATTTTTCTATAGATTTTTCAGATTTAGAAAATATAATA
GAAAAAGAAAAGCCTAAGGTTATGGTATTATCTTATCCATCTAATCCAACAGGGGCTATACTTTCTAAAGAAGAAAGTTG
TAAGTTACATAAAATAATAAAAGAAAATAATATTATAGTAATAAGTGATGAAATGTATGCCTCTTTATGTTTTGAAGAAA
AATATTATTCTATAGCTCAATTTGAAGATATAAAAGATAAGGTTATATTAGTTAGTGGATTTTCAAAGATGTTTTCAATG
ACTGGACTTAGAATAGGGTATGTTTGTGCAAATGATGAGTTCATAAATTCTATAATAAAAGTTCATCAATATAATGTATC
TTGTGCGCCTTCTATATGTCAGTGGGGAGCATATGCAGGGTTAAAATACTGCATGAAAGATGTAGATTGTATGAAAGAAG
AGTTTATAAAAAGAAGAGACTTTGTATATGATAGATTAAAGTACATGAGTATAGATACATATCTCCCTAATGGAGCTTTT
TATATGTTTCCTTCCATAAAAAAATATAATATGACTAGTGAAGAATTTTGTGAAAGACTTTTGAAGGAAGCTAAAGTGGC
TATAGTTCCTGGCTCAGCCTTTGGGGAAATGGGAGAGGGATATATTAGAATATCTTATGCCTATAGCATGGAAGAATTAA
ATGAAGCACTAAATAGAATGGAAGCATGGCTAAGTAAAATCACAATGTAA

Upstream 100 bases:

>100_bases
TGGAGATTTAATAAAATATATTGGTTCTAAGATCGTAAAAAATATAAAGGGAAAGGAGAAGTTATGGTTTATTAATATTC
CCATAACATGATAATATTTT

Downstream 100 bases:

>100_bases
GGAAATTACGATTTAAAAGAGTATATATTACCCGTGATTTAAAAAAGGGATATATGGTTAAAAAGGCAATTCGCTTCAAT
AATAGATTCTAATTTGTTTT

Product: aminotransferase, classes I and II

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDYIKTEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPSRIKDELINSIQEDKTTYTSNAGLKELRLEIA
RYLKTMNINYNSEEICITVGGSEGLMCVFSTLLNEGDKVLIPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENII
EKEKPKVMVLSYPSNPTGAILSKEESCKLHKIIKENNIIVISDEMYASLCFEEKYYSIAQFEDIKDKVILVSGFSKMFSM
TGLRIGYVCANDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMKDVDCMKEEFIKRRDFVYDRLKYMSIDTYLPNGAF
YMFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEGYIRISYAYSMEELNEALNRMEAWLSKITM

Sequences:

>Translated_389_residues
MDYIKTEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPSRIKDELINSIQEDKTTYTSNAGLKELRLEIA
RYLKTMNINYNSEEICITVGGSEGLMCVFSTLLNEGDKVLIPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENII
EKEKPKVMVLSYPSNPTGAILSKEESCKLHKIIKENNIIVISDEMYASLCFEEKYYSIAQFEDIKDKVILVSGFSKMFSM
TGLRIGYVCANDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMKDVDCMKEEFIKRRDFVYDRLKYMSIDTYLPNGAF
YMFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEGYIRISYAYSMEELNEALNRMEAWLSKITM
>Mature_389_residues
MDYIKTEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPSRIKDELINSIQEDKTTYTSNAGLKELRLEIA
RYLKTMNINYNSEEICITVGGSEGLMCVFSTLLNEGDKVLIPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENII
EKEKPKVMVLSYPSNPTGAILSKEESCKLHKIIKENNIIVISDEMYASLCFEEKYYSIAQFEDIKDKVILVSGFSKMFSM
TGLRIGYVCANDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMKDVDCMKEEFIKRRDFVYDRLKYMSIDTYLPNGAF
YMFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEGYIRISYAYSMEELNEALNRMEAWLSKITM

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=399, Percent_Identity=24.812030075188, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI56713254, Length=399, Percent_Identity=24.812030075188, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI95147551, Length=404, Percent_Identity=21.5346534653465, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI169881279, Length=404, Percent_Identity=21.5346534653465, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=23.0769230769231, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI7705897, Length=343, Percent_Identity=24.198250728863, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI33469970, Length=343, Percent_Identity=24.198250728863, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI187936925, Length=391, Percent_Identity=24.0409207161125, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI14211921, Length=391, Percent_Identity=24.0409207161125, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI19263340, Length=366, Percent_Identity=22.4043715846995, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI215599424, Length=366, Percent_Identity=22.4043715846995, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI169881281, Length=315, Percent_Identity=20, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI149944424, Length=368, Percent_Identity=22.0108695652174, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1788722, Length=364, Percent_Identity=28.8461538461538, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1786816, Length=363, Percent_Identity=24.5179063360882, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1788627, Length=374, Percent_Identity=26.2032085561497, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787909, Length=261, Percent_Identity=22.2222222222222, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790797, Length=392, Percent_Identity=22.9591836734694, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787710, Length=182, Percent_Identity=28.021978021978, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788332, Length=170, Percent_Identity=24.7058823529412, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=364, Percent_Identity=26.6483516483516, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=364, Percent_Identity=26.6483516483516, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=25.1351351351351, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=367, Percent_Identity=25.0681198910082, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71981209, Length=377, Percent_Identity=25.1989389920424, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71981215, Length=218, Percent_Identity=28.4403669724771, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=328, Percent_Identity=24.0853658536585, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323118, Length=377, Percent_Identity=25.4641909814324, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320317, Length=362, Percent_Identity=25.1381215469613, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=24.8062015503876, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=24.8062015503876, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=24.8062015503876, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=24.8062015503876, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24641770, Length=368, Percent_Identity=25, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641760, Length=368, Percent_Identity=25, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641768, Length=368, Percent_Identity=25, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641766, Length=368, Percent_Identity=25, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641764, Length=368, Percent_Identity=25, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45551451, Length=368, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=23.5924932975871, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 44597; Mature: 44597

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYIKTEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPSRIKDELINSIQ
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHEEEECCCCCCCCHHHHHHHHHHHHH
EDKTTYTSNAGLKELRLEIARYLKTMNINYNSEEICITVGGSEGLMCVFSTLLNEGDKVL
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEE
IPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENIIEKEKPKVMVLSYPSNPTGAI
EECCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCE
LSKEESCKLHKIIKENNIIVISDEMYASLCFEEKYYSIAQFEDIKDKVILVSGFSKMFSM
ECCCCCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHH
TGLRIGYVCANDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMKDVDCMKEEFIKRRD
CCCEEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVYDRLKYMSIDTYLPNGAFYMFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEG
HHHHHHHHEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHCCCCC
YIRISYAYSMEELNEALNRMEAWLSKITM
EEEEEEEECHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYIKTEEIISEKVKNIEISGIRRFFNKVSNYKDVISLTLGQPDFKLPSRIKDELINSIQ
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHEEEECCCCCCCCHHHHHHHHHHHHH
EDKTTYTSNAGLKELRLEIARYLKTMNINYNSEEICITVGGSEGLMCVFSTLLNEGDKVL
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEE
IPTPAYPAYESCVKLLGGQILNYKLKNDFSIDFSDLENIIEKEKPKVMVLSYPSNPTGAI
EECCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCE
LSKEESCKLHKIIKENNIIVISDEMYASLCFEEKYYSIAQFEDIKDKVILVSGFSKMFSM
ECCCCCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHH
TGLRIGYVCANDEFINSIIKVHQYNVSCAPSICQWGAYAGLKYCMKDVDCMKEEFIKRRD
CCCEEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVYDRLKYMSIDTYLPNGAFYMFPSIKKYNMTSEEFCERLLKEAKVAIVPGSAFGEMGEG
HHHHHHHHEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHCCCCC
YIRISYAYSMEELNEALNRMEAWLSKITM
EEEEEEEECHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]