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The map label for this gene is pbuX [H]

Identifier: 148380843

GI number: 148380843

Start: 3075213

End: 3076619

Strand: Reverse

Name: pbuX [H]

Synonym: CBO2887

Alternate gene names: 148380843

Gene position: 3076619-3075213 (Counterclockwise)

Preceding gene: 148380844

Following gene: 148380842

Centisome position: 79.15

GC content: 33.26

Gene sequence:

>1407_bases
ATGGATAATAAAGTAAATAAAGCAATAGCTCCTGTTGACGAAGTACTTCCACCACAGCAGTTATTTATTTTAGGTTTACA
ACATGTATTGGCAATGTGTGCAGGTGCGGTTGCTGTTCCTCTAATAGTAGGTGGTGCACTAAATTTGTCTGCAGAACAGA
CAATATTTCTTATAAATGCAGATCTTTTTGTAGCAGGTATAGCAACGCTAGTACAATCTCTAGGGATAAAAAATTTTATT
GGGGCAAAAGTTCCTGTTATTGAAGGTGCAAGTTTTGCGTCTGTATCGGTCATGATAGCTATTGCAAATACTTATCCAGG
GGATCCTATTACAGCTATTACAACTATTTTTGGAGCTACCTTTGTAGCTGGGTTATTTTGTTTTATTATGGCACCTTTCT
TCGGAAAGCTTATAAGATTTTTCCCTAAGGTAGTAACAGGTACTGTAATAACTATAATAGGCATCTCATTGCTTCCAGTA
GCAGTGAGATGGTGTGCGGGCAATGATGTAAATTCTTCTAAATTTGCTAGCCCTAAAAATATTTTATTAGCTTTGTTTGT
TTTAATTCTAATTTTAATTATGTATAAATTTTTCAAAGGAATTTTAGGAAATATATCTATACTATTAGGGATAGTTGTAG
GAACTATTGTTGCTTCAATGTTAGGAATGTCAGATTTTAGTAGAGTTCATAGTTCAGGATGGATTAATATAGATATTCCC
TTATATTTTGGTGCTCTTAAATTTAATTTGACAGCTATAATTTCAATGATATTAGTTATGTTAGTCATGATGACAGAAGC
TACAGGAAATATGATAGCTATACACGAAATGGTTGGAAAGGATATTGATGATAAAAATTTAACTAGAGGTCTTAGAACAG
ATGGGTTTGCTACAATGCTTGCAGGTATATTTAATACATTCCCTCATACTGCTTTTGGCCAAAATGTAGGTCTCGTAAAT
TTGACAGGTATAAAGAGTCGTTTCGTAGTAGCAGCTTCAGGAGGAATTCTAATATTATTAGGATTATTTCCAAAAGCAGG
AGCAGTAGTTGCGTCTATACCATATCCTGTCCTTGGTGGCGCTGGTATAGCCATGTTTGGTATGGTAACTTCAGGGGGTA
TTTCAAGTCTTAGTAAGGTTGAATTTAATGGAACTAAAAATGGAATGATAATAGCAGTAAGTATTGGCCTTGCTATGATT
CCTTTAGCAGTACCAACTTTTTATAGTAAATTTCCACAATGGGTGGAAACTCTTTTCCACAGTGGCATAACAACTGGTAG
TTTAACAGCAATACTTTTAAATTTATTCTTTAATGAACTTGGAAAGAATAAAAATTTATCAGTAAAAGACGATAAAGAAA
ATAGCTATAAAATAGAAGTAGCTGATAAAGAAACAAAAAATATATAA

Upstream 100 bases:

>100_bases
ACTTTTATTTAGTACTGAAGGTGACACAGATCCAGATAAATATAGAAAAATTGTTTGGAATGGTGAATATTCAAAATAAA
GAATTCATGGGGGTATAAAA

Downstream 100 bases:

>100_bases
GTTTAAAATCATTTTTCACAATATTCACAAAAGGAGATGCGATTTTAAGATGGCCACTTTAATAAAAAATGGAATTATTG
TTACTTCAGGAGATACCTTT

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MDNKVNKAIAPVDEVLPPQQLFILGLQHVLAMCAGAVAVPLIVGGALNLSAEQTIFLINADLFVAGIATLVQSLGIKNFI
GAKVPVIEGASFASVSVMIAIANTYPGDPITAITTIFGATFVAGLFCFIMAPFFGKLIRFFPKVVTGTVITIIGISLLPV
AVRWCAGNDVNSSKFASPKNILLALFVLILILIMYKFFKGILGNISILLGIVVGTIVASMLGMSDFSRVHSSGWINIDIP
LYFGALKFNLTAIISMILVMLVMMTEATGNMIAIHEMVGKDIDDKNLTRGLRTDGFATMLAGIFNTFPHTAFGQNVGLVN
LTGIKSRFVVAASGGILILLGLFPKAGAVVASIPYPVLGGAGIAMFGMVTSGGISSLSKVEFNGTKNGMIIAVSIGLAMI
PLAVPTFYSKFPQWVETLFHSGITTGSLTAILLNLFFNELGKNKNLSVKDDKENSYKIEVADKETKNI

Sequences:

>Translated_468_residues
MDNKVNKAIAPVDEVLPPQQLFILGLQHVLAMCAGAVAVPLIVGGALNLSAEQTIFLINADLFVAGIATLVQSLGIKNFI
GAKVPVIEGASFASVSVMIAIANTYPGDPITAITTIFGATFVAGLFCFIMAPFFGKLIRFFPKVVTGTVITIIGISLLPV
AVRWCAGNDVNSSKFASPKNILLALFVLILILIMYKFFKGILGNISILLGIVVGTIVASMLGMSDFSRVHSSGWINIDIP
LYFGALKFNLTAIISMILVMLVMMTEATGNMIAIHEMVGKDIDDKNLTRGLRTDGFATMLAGIFNTFPHTAFGQNVGLVN
LTGIKSRFVVAASGGILILLGLFPKAGAVVASIPYPVLGGAGIAMFGMVTSGGISSLSKVEFNGTKNGMIIAVSIGLAMI
PLAVPTFYSKFPQWVETLFHSGITTGSLTAILLNLFFNELGKNKNLSVKDDKENSYKIEVADKETKNI
>Mature_468_residues
MDNKVNKAIAPVDEVLPPQQLFILGLQHVLAMCAGAVAVPLIVGGALNLSAEQTIFLINADLFVAGIATLVQSLGIKNFI
GAKVPVIEGASFASVSVMIAIANTYPGDPITAITTIFGATFVAGLFCFIMAPFFGKLIRFFPKVVTGTVITIIGISLLPV
AVRWCAGNDVNSSKFASPKNILLALFVLILILIMYKFFKGILGNISILLGIVVGTIVASMLGMSDFSRVHSSGWINIDIP
LYFGALKFNLTAIISMILVMLVMMTEATGNMIAIHEMVGKDIDDKNLTRGLRTDGFATMLAGIFNTFPHTAFGQNVGLVN
LTGIKSRFVVAASGGILILLGLFPKAGAVVASIPYPVLGGAGIAMFGMVTSGGISSLSKVEFNGTKNGMIIAVSIGLAMI
PLAVPTFYSKFPQWVETLFHSGITTGSLTAILLNLFFNELGKNKNLSVKDDKENSYKIEVADKETKNI

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=441, Percent_Identity=25.8503401360544, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI44680143, Length=441, Percent_Identity=25.6235827664399, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI44680148, Length=181, Percent_Identity=25.9668508287293, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI40316845, Length=181, Percent_Identity=25.9668508287293, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI87082181, Length=468, Percent_Identity=41.8803418803419, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1790087, Length=432, Percent_Identity=31.4814814814815, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI87082178, Length=447, Percent_Identity=29.7539149888143, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87081818, Length=445, Percent_Identity=29.438202247191, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788843, Length=389, Percent_Identity=28.0205655526992, Blast_Score=122, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71993493, Length=464, Percent_Identity=26.0775862068966, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17541904, Length=442, Percent_Identity=23.5294117647059, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17542262, Length=450, Percent_Identity=22.2222222222222, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17542260, Length=235, Percent_Identity=28.0851063829787, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17558856, Length=217, Percent_Identity=25.3456221198157, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356175, Length=451, Percent_Identity=25.0554323725055, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 49578; Mature: 49578

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKVNKAIAPVDEVLPPQQLFILGLQHVLAMCAGAVAVPLIVGGALNLSAEQTIFLINA
CCCCHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
DLFVAGIATLVQSLGIKNFIGAKVPVIEGASFASVSVMIAIANTYPGDPITAITTIFGAT
HHHHHHHHHHHHHCCCHHHCCCCCCEECCCCHHEEEEEEEEECCCCCCHHHHHHHHHHHH
FVAGLFCFIMAPFFGKLIRFFPKVVTGTVITIIGISLLPVAVRWCAGNDVNSSKFASPKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
ILLALFVLILILIMYKFFKGILGNISILLGIVVGTIVASMLGMSDFSRVHSSGWINIDIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEHH
LYFGALKFNLTAIISMILVMLVMMTEATGNMIAIHEMVGKDIDDKNLTRGLRTDGFATML
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHCCCCCCHHHHHH
AGIFNTFPHTAFGQNVGLVNLTGIKSRFVVAASGGILILLGLFPKAGAVVASIPYPVLGG
HHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCCCCEEEECCCCCCCC
AGIAMFGMVTSGGISSLSKVEFNGTKNGMIIAVSIGLAMIPLAVPTFYSKFPQWVETLFH
CHHHHHHHHHCCCCCHHHEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SGITTGSLTAILLNLFFNELGKNKNLSVKDDKENSYKIEVADKETKNI
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MDNKVNKAIAPVDEVLPPQQLFILGLQHVLAMCAGAVAVPLIVGGALNLSAEQTIFLINA
CCCCHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
DLFVAGIATLVQSLGIKNFIGAKVPVIEGASFASVSVMIAIANTYPGDPITAITTIFGAT
HHHHHHHHHHHHHCCCHHHCCCCCCEECCCCHHEEEEEEEEECCCCCCHHHHHHHHHHHH
FVAGLFCFIMAPFFGKLIRFFPKVVTGTVITIIGISLLPVAVRWCAGNDVNSSKFASPKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
ILLALFVLILILIMYKFFKGILGNISILLGIVVGTIVASMLGMSDFSRVHSSGWINIDIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEHH
LYFGALKFNLTAIISMILVMLVMMTEATGNMIAIHEMVGKDIDDKNLTRGLRTDGFATML
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHCCCCCCHHHHHH
AGIFNTFPHTAFGQNVGLVNLTGIKSRFVVAASGGILILLGLFPKAGAVVASIPYPVLGG
HHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEEECCCCCCCEEEECCCCCCCC
AGIAMFGMVTSGGISSLSKVEFNGTKNGMIIAVSIGLAMIPLAVPTFYSKFPQWVETLFH
CHHHHHHHHHCCCCCHHHEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SGITTGSLTAILLNLFFNELGKNKNLSVKDDKENSYKIEVADKETKNI
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]