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The map label for this gene is mcpB [H]

Identifier: 148380425

GI number: 148380425

Start: 2601785

End: 2603812

Strand: Reverse

Name: mcpB [H]

Synonym: CBO2468

Alternate gene names: 148380425

Gene position: 2603812-2601785 (Counterclockwise)

Preceding gene: 148380426

Following gene: 148380424

Centisome position: 66.99

GC content: 28.75

Gene sequence:

>2028_bases
ATGAAAATATTGAAAAAACTGTCCTTTAAAATGAAATTATTAATTACGATTTTACCAGTTGTAATAATTGGAATGTCAAT
TTTGAGTTTTACAACATTTTATGAATTTAGAAAAAATATTGAAAATGAACTTATAAATAATAAATTGAAGGAAGGGAAAA
AATTAACTGAGAGTATAAACAATTGGTTAGAAGGAAAGCTTTTAGAAGTAAGAAGTTCTGCTAATACACCTACGGCAAAA
CTAATAGAAACAGATGTTTCTGCTGTAGATAATTTTAATGCAGAAAGAATTAAATTTTTAGAAAAAAATTATCCAGGAGA
ATATGACAATGCAGCAGCAACTTTATTTAATAATGATGGTAAATCTAGAGCTCAATATTCAAATGGAAAGTTTGTAAATG
GCGATGTATCAGAAAAAACATGGTACAAGGATTTAATGAGTGGTGTACCATATAATATATCTAATCCTGTAGTATCAAAG
GGAACTGGTAAAACTTTGGTTGTAATAGGAGTTCCAATTAAAAACAAATCAGAAAAGACAATAGGAACAATGATATCTGC
TGTGAATCTTTTACATATTAAAGAAAAAGTTAAGGAATTTAAATTTGGTGAAAAAGGATATAGTTTATTAATTGGAAAGG
ATGGAACTATTCTTGAACATCCAGATAAGTCATTAGTAATGCAAAAAAAGATATCAGAAATAAAAGATGAAAATATACAA
TCATTAGGAAAAGAAATGATGGAAAATAAATCAGGTGTATTTAGATTTGGAAGTGGAGATAATAAATCGATTGTATTTTA
TAATAAAGTTCCTCTATCGGGGTGGAATGTAGCAAGTGTTGTGTCTGAAAAGGAATTGTTCGCTCCTTTAAATAAATTAA
TGTTAACATTAATTTTGATAACAATAGTAATTGTATTGATTGTTGCAACAGTAATTGTACTTGTAGCAAAACAAATCACA
TTACCATTAACTAAGTTATCTGATTTTGCAGAAGAAATAGCAGAAGGAAATCTTACAAATAAATTAGAAGTTCATGGGCA
AGACGAAATTTCTAAGGTGACAAAAGCACTAAATAATACAGTTTTAAAGCTTAAAAAAATGATAGGTGATATAAGTAGTT
CGGCTAATGATGTTATGGTAATATCTAATGGTTTAGCATCATCAACAAGTGAATCATTAAAGGGAAATGAAGAAGTTTCA
CGAAGTATGCAAGAAATAGCCACAGGGGCTGTATCTCAGGCAGAAGGGGCAAGCAAAGCATCTATTGTAACAAGAGAATT
AGTTGAAGATATAAATGAAATATCTAAAAAATGTAATTATATGATTAACATAGTGGAAAAATCAACTAATAGAAGCACAA
AAGTTTCACAAGGAGTCCAACAAACTGTAGATAGTATAAAGAATATAGCTACAACAAATAAACATAATGTTGAAGAAATT
CAAAATTTATTAAATCAATCTAAAGAAATAGGACAAATTGTTGATGTAATAAGTGATATATCTGAACAAACTAATCTTTT
ATCACTTAATGCAGCTATTGAAGCTGCTAGGGCTGGTGCACAAGGTAGAGGATTTGCTGTAGTCGCAGATGAGGTGAGGA
AATTAGCAGAACAGTCAAGTAATTCTTCAAAAAGGATAGTAGAGCTTATTAATGGAATTCAAAAACAAATTGAAATCATA
TCAAATAAAATGAATTCTGGAACAAGTGAAGTTATGCATGGAGTTAAAATGGCAACATTAATTGGTAATGATTTTGAAGA
AATAGAGAAAGTATTTAATGAAGTTAATAATATTGTATCAGAGGTATCAGAGTCTACTAATACGATGGAAAAGAAAGTAA
ATACTACAGCTGATATTATAAATAATGTTGCAGCTGTAACAGAAGAGAATTCAGCAGCTACAGAAGAAGTCACTGCATCA
AATGAAGAGCAGATTGCTTTTATGCATCAAATTGTAGACTCAACTTATACATTAGAAGAATTAGTTAAAAAACTTAAGGA
TACAGTATATAAATTTAAATTATCCTAG

Upstream 100 bases:

>100_bases
AAAGACAACTATTAAAAATAATTAATTTATATAAATATGTTTGTTAATTTTAGATAAGTTTTATGAAAATGTATATCTTA
CAAATGGAATTACGGGAGTG

Downstream 100 bases:

>100_bases
ATAGAATTAAAAGTAATTTATATAGAAAGCTTATAATCTTACAAAATAAAGATTATAAGCTTTTTTTATTGAATCTTTTA
GAAATATCTACAAAAATAGA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MKILKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINNKLKEGKKLTESINNWLEGKLLEVRSSANTPTAK
LIETDVSAVDNFNAERIKFLEKNYPGEYDNAAATLFNNDGKSRAQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSK
GTGKTLVVIGVPIKNKSEKTIGTMISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSLVMQKKISEIKDENIQ
SLGKEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEKELFAPLNKLMLTLILITIVIVLIVATVIVLVAKQIT
LPLTKLSDFAEEIAEGNLTNKLEVHGQDEISKVTKALNNTVLKLKKMIGDISSSANDVMVISNGLASSTSESLKGNEEVS
RSMQEIATGAVSQAEGASKASIVTRELVEDINEISKKCNYMINIVEKSTNRSTKVSQGVQQTVDSIKNIATTNKHNVEEI
QNLLNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGAQGRGFAVVADEVRKLAEQSSNSSKRIVELINGIQKQIEII
SNKMNSGTSEVMHGVKMATLIGNDFEEIEKVFNEVNNIVSEVSESTNTMEKKVNTTADIINNVAAVTEENSAATEEVTAS
NEEQIAFMHQIVDSTYTLEELVKKLKDTVYKFKLS

Sequences:

>Translated_675_residues
MKILKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINNKLKEGKKLTESINNWLEGKLLEVRSSANTPTAK
LIETDVSAVDNFNAERIKFLEKNYPGEYDNAAATLFNNDGKSRAQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSK
GTGKTLVVIGVPIKNKSEKTIGTMISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSLVMQKKISEIKDENIQ
SLGKEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEKELFAPLNKLMLTLILITIVIVLIVATVIVLVAKQIT
LPLTKLSDFAEEIAEGNLTNKLEVHGQDEISKVTKALNNTVLKLKKMIGDISSSANDVMVISNGLASSTSESLKGNEEVS
RSMQEIATGAVSQAEGASKASIVTRELVEDINEISKKCNYMINIVEKSTNRSTKVSQGVQQTVDSIKNIATTNKHNVEEI
QNLLNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGAQGRGFAVVADEVRKLAEQSSNSSKRIVELINGIQKQIEII
SNKMNSGTSEVMHGVKMATLIGNDFEEIEKVFNEVNNIVSEVSESTNTMEKKVNTTADIINNVAAVTEENSAATEEVTAS
NEEQIAFMHQIVDSTYTLEELVKKLKDTVYKFKLS
>Mature_675_residues
MKILKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINNKLKEGKKLTESINNWLEGKLLEVRSSANTPTAK
LIETDVSAVDNFNAERIKFLEKNYPGEYDNAAATLFNNDGKSRAQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSK
GTGKTLVVIGVPIKNKSEKTIGTMISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSLVMQKKISEIKDENIQ
SLGKEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEKELFAPLNKLMLTLILITIVIVLIVATVIVLVAKQIT
LPLTKLSDFAEEIAEGNLTNKLEVHGQDEISKVTKALNNTVLKLKKMIGDISSSANDVMVISNGLASSTSESLKGNEEVS
RSMQEIATGAVSQAEGASKASIVTRELVEDINEISKKCNYMINIVEKSTNRSTKVSQGVQQTVDSIKNIATTNKHNVEEI
QNLLNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGAQGRGFAVVADEVRKLAEQSSNSSKRIVELINGIQKQIEII
SNKMNSGTSEVMHGVKMATLIGNDFEEIEKVFNEVNNIVSEVSESTNTMEKKVNTTADIINNVAAVTEENSAATEEVTAS
NEEQIAFMHQIVDSTYTLEELVKKLKDTVYKFKLS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=350, Percent_Identity=26.5714285714286, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1787690, Length=373, Percent_Identity=26.8096514745308, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1788194, Length=354, Percent_Identity=28.2485875706215, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788195, Length=325, Percent_Identity=26.7692307692308, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1789453, Length=372, Percent_Identity=25.8064516129032, Blast_Score=105, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 74270; Mature: 74270

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINNKLKEGKKLTESIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NWLEGKLLEVRSSANTPTAKLIETDVSAVDNFNAERIKFLEKNYPGEYDNAAATLFNNDG
HHHCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCC
KSRAQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSKGTGKTLVVIGVPIKNKSEKT
CCHHHCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHH
IGTMISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSLVMQKKISEIKDENIQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHH
SLGKEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEKELFAPLNKLMLTLILI
HHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TIVIVLIVATVIVLVAKQITLPLTKLSDFAEEIAEGNLTNKLEVHGQDEISKVTKALNNT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHH
VLKLKKMIGDISSSANDVMVISNGLASSTSESLKGNEEVSRSMQEIATGAVSQAEGASKA
HHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHH
SIVTRELVEDINEISKKCNYMINIVEKSTNRSTKVSQGVQQTVDSIKNIATTNKHNVEEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
QNLLNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGAQGRGFAVVADEVRKLAEQSS
HHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCC
NSSKRIVELINGIQKQIEIISNKMNSGTSEVMHGVKMATLIGNDFEEIEKVFNEVNNIVS
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EVSESTNTMEKKVNTTADIINNVAAVTEENSAATEEVTASNEEQIAFMHQIVDSTYTLEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCHHHHHH
LVKKLKDTVYKFKLS
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MKILKKLSFKMKLLITILPVVIIGMSILSFTTFYEFRKNIENELINNKLKEGKKLTESIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NWLEGKLLEVRSSANTPTAKLIETDVSAVDNFNAERIKFLEKNYPGEYDNAAATLFNNDG
HHHCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCC
KSRAQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSKGTGKTLVVIGVPIKNKSEKT
CCHHHCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHH
IGTMISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSLVMQKKISEIKDENIQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHH
SLGKEMMENKSGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEKELFAPLNKLMLTLILI
HHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TIVIVLIVATVIVLVAKQITLPLTKLSDFAEEIAEGNLTNKLEVHGQDEISKVTKALNNT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHH
VLKLKKMIGDISSSANDVMVISNGLASSTSESLKGNEEVSRSMQEIATGAVSQAEGASKA
HHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHH
SIVTRELVEDINEISKKCNYMINIVEKSTNRSTKVSQGVQQTVDSIKNIATTNKHNVEEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
QNLLNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGAQGRGFAVVADEVRKLAEQSS
HHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCC
NSSKRIVELINGIQKQIEIISNKMNSGTSEVMHGVKMATLIGNDFEEIEKVFNEVNNIVS
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EVSESTNTMEKKVNTTADIINNVAAVTEENSAATEEVTASNEEQIAFMHQIVDSTYTLEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCHHHHHH
LVKKLKDTVYKFKLS
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]