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The map label for this gene is bdh [H]

Identifier: 148379383

GI number: 148379383

Start: 1533571

End: 1534734

Strand: Direct

Name: bdh [H]

Synonym: CBO1407

Alternate gene names: 148379383

Gene position: 1533571-1534734 (Clockwise)

Preceding gene: 148379381

Following gene: 148379384

Centisome position: 39.45

GC content: 31.62

Gene sequence:

>1164_bases
ATGCTAAATTTTAATTATTCTATACCAACAAAAATTTTTTTTGGTAAAAACCAAATAAGTGTTTTAGGAGAGCAAATAAA
AAAATATGGATCAAGGGTATTGCTTACTTATGGTGGAGGAAGTATAAAAAAGAATGGAGTATATGATAAAGTTATAAAAA
TTTTAAAGAGCAATAATATAGGATTTGTTGAGCTTTCAGGAATAGATCCTAATCCAAGAGTAACTAGTGTAAGGGCAGGA
GTAAAATTATGCAAAGAAAATAATATAGATTTCATATTAGCAGTAGGAGGAGGAAGTACTATAGATTGCTCAAAGGTAAT
AGCTGCATCATATTATTATGAAGGAGATCCTTGGGATATAGTAATTAAAAAAGCTAAAATAAATAAGGCATTACCTATAG
GAAGTATATTAACACTAGCTGCCACTGGCTCAGAAATGGATGCTGGAGCAGTAATTAGTAATATGGATACTAATGAGAAA
ATAGGAGTAGGACATCCTTCCATGGCCCCTAAATTTTCCATACTAGATCCAGAATATACTTTTACAGTGCCTAAAAATCA
AACAGCAGCAGGAACTGCAGATATAATGAGTCATATATTTGAAGCCTATTTCAGTAAGACAAAGGAAGCTTATATTCAAA
ATAGAATGGCAGAGGCTATTTTAAAAACTTGTATAAAGTATGGGAAGGTAGCTATAAAAGAGCCAGAAAATTATGAAGCT
AGGGCTAACCTTATGTGGGCATCTAGCTTAGCTATAAATGGATTATTAAGTTATGGTAAATCAGAACCTTGGAGTGTACA
CCCTATGGAACATGAATTGAGTGCTTTTTATGATATAACTCATGGTGTGGGGTTAGCTATATTAACGCCAAATTGGATGA
AATATGTTTTGGGCGATGAAAATGTAAATGATTTTTATGAATATGGAGTAAATGTTTGGGATATGAATCCAGAAGAAAGC
AAATATGAAGTAGCACAAAAGGCTATAGAAAAAACTCGAGAATATTTTATAGAATTAGGAATTCCAGCCACATTAAAAGA
AGTAGGTATAGGAGAAGAAAAACTAGAACAAATGGCAGAGGCTGCTACAAGAAATGGAACTTTAGATGGTTTTAAACCTT
TAAGTACTGAAGATATTTTAAATATATATAAATTATCACTTTAA

Upstream 100 bases:

>100_bases
GTTTTAGGTAATGACATAGAGACACAAGTGATGTTGTAGTATATGCTTTTAAACTATTTCTTAAAATAATATTTAATTAA
AGATAATGGGAGGAGAAATA

Downstream 100 bases:

>100_bases
CTTTAATATAGAATATATACCTATGTTAGGTAATTTTTGATTTTAAATATAGTTTCATTAGAAATAATTATCATTGAAAT
TTAAAATTATTTATTTAAGA

Product: NADH-dependent butanol dehydrogenase

Products: NA

Alternate protein names: BDH I [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MLNFNYSIPTKIFFGKNQISVLGEQIKKYGSRVLLTYGGGSIKKNGVYDKVIKILKSNNIGFVELSGIDPNPRVTSVRAG
VKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDIVIKKAKINKALPIGSILTLAATGSEMDAGAVISNMDTNEK
IGVGHPSMAPKFSILDPEYTFTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIKYGKVAIKEPENYEA
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLGDENVNDFYEYGVNVWDMNPEES
KYEVAQKAIEKTREYFIELGIPATLKEVGIGEEKLEQMAEAATRNGTLDGFKPLSTEDILNIYKLSL

Sequences:

>Translated_387_residues
MLNFNYSIPTKIFFGKNQISVLGEQIKKYGSRVLLTYGGGSIKKNGVYDKVIKILKSNNIGFVELSGIDPNPRVTSVRAG
VKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDIVIKKAKINKALPIGSILTLAATGSEMDAGAVISNMDTNEK
IGVGHPSMAPKFSILDPEYTFTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIKYGKVAIKEPENYEA
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLGDENVNDFYEYGVNVWDMNPEES
KYEVAQKAIEKTREYFIELGIPATLKEVGIGEEKLEQMAEAATRNGTLDGFKPLSTEDILNIYKLSL
>Mature_387_residues
MLNFNYSIPTKIFFGKNQISVLGEQIKKYGSRVLLTYGGGSIKKNGVYDKVIKILKSNNIGFVELSGIDPNPRVTSVRAG
VKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDIVIKKAKINKALPIGSILTLAATGSEMDAGAVISNMDTNEK
IGVGHPSMAPKFSILDPEYTFTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIKYGKVAIKEPENYEA
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLGDENVNDFYEYGVNVWDMNPEES
KYEVAQKAIEKTREYFIELGIPATLKEVGIGEEKLEQMAEAATRNGTLDGFKPLSTEDILNIYKLSL

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=429, Percent_Identity=20.04662004662, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789386, Length=354, Percent_Identity=44.0677966101695, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI48994951, Length=390, Percent_Identity=29.7435897435897, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789163, Length=383, Percent_Identity=25.8485639686684, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787493, Length=376, Percent_Identity=23.6702127659574, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082107, Length=388, Percent_Identity=25, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17537053, Length=425, Percent_Identity=24, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6321181, Length=366, Percent_Identity=27.8688524590164, Blast_Score=123, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42742; Mature: 42742

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFNYSIPTKIFFGKNQISVLGEQIKKYGSRVLLTYGGGSIKKNGVYDKVIKILKSNNI
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCC
GFVELSGIDPNPRVTSVRAGVKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDI
CEEEECCCCCCCCEEHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHEEECCCCCEE
VIKKAKINKALPIGSILTLAATGSEMDAGAVISNMDTNEKIGVGHPSMAPKFSILDPEYT
EEEEECCCCCCCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCEE
FTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIKYGKVAIKEPENYEA
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLGDE
CEEEEEHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCEEEEECCCHHEEECCCC
NVNDFYEYGVNVWDMNPEESKYEVAQKAIEKTREYFIELGIPATLKEVGIGEEKLEQMAE
CHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCHHHHHHHHH
AATRNGTLDGFKPLSTEDILNIYKLSL
HHHCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MLNFNYSIPTKIFFGKNQISVLGEQIKKYGSRVLLTYGGGSIKKNGVYDKVIKILKSNNI
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCC
GFVELSGIDPNPRVTSVRAGVKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDI
CEEEECCCCCCCCEEHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHEEECCCCCEE
VIKKAKINKALPIGSILTLAATGSEMDAGAVISNMDTNEKIGVGHPSMAPKFSILDPEYT
EEEEECCCCCCCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCEE
FTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIKYGKVAIKEPENYEA
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLGDE
CEEEEEHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCEEEEECCCHHEEECCCC
NVNDFYEYGVNVWDMNPEESKYEVAQKAIEKTREYFIELGIPATLKEVGIGEEKLEQMAE
CHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCHHHHHHHHH
AATRNGTLDGFKPLSTEDILNIYKLSL
HHHCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385386; 11466286; 1809209 [H]