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The map label for this gene is ahpC [C]

Identifier: 148361306

GI number: 148361306

Start: 3531586

End: 3532191

Strand: Reverse

Name: ahpC [C]

Synonym: LPC_3280

Alternate gene names: 148361306

Gene position: 3532191-3531586 (Counterclockwise)

Preceding gene: 148361307

Following gene: 148361303

Centisome position: 98.76

GC content: 40.76

Gene sequence:

>606_bases
ATGAGTGTCTTAGTTGGGCGTAAAGCACCTGATTTTACTGTGGCTGCAGTAATGGGCAATGGGGAAATTGTTGATAAATT
CAATTTACACGAACATTTAAAAGGCAAATACGGATTAGTTTTCTTTTATCCCCTGGATTTTACTTTTGTATGTCCTTCCG
AGTTAATTGCTCTTGATCATCGTATCGAAGAGTTCAAAAGACGTAATGTTGAAGTGGTTGCTGTATCTATTGATTCACAT
TTTACCCATAATGCGTATAGGAATACTCCTGTGAAAAATGGTGGAATAGGGCCAGTGAGATTTACTTTGGCAGCTGACAT
GACTCATAGTATTTGCCAATCCTATGGTGTAGAACATCCAGTTGCTGGTGTGGCTTTCCGAGGCGCTTTTGTTATCGATA
CGAACGGTATGGTTCGTTCGCAAATCGTCAATGACTTGCCGATAGGAAGAAATATTGATGAGATTCTTCGTATCATAGAT
GCAGTTCAATTCTTTGAAGAAAATGGTGAGGTTTGTCCTGCTGGCTGGCAAAAAGGACAAGCTGGTATGAAAGCGTCTCC
TAAAGGTGTTGCAGAATACCTGTCTGAGCACTCCGAGTCCTTGTAA

Upstream 100 bases:

>100_bases
CAGCAAGGAGAGTTAGAGCCTATGTTGCGTGATGCAGTAGCGGCATAATTTTAATAACAATTGTGGGATTTACTCACCCA
CCGCTAATGGAGATAATAGA

Downstream 100 bases:

>100_bases
TATAAGACAAGGAAATGGGGTCTTTTTGTTGTTGTGTTTTATTGAGAAGCATAACACAAGAAAATTTCTATCAAACTCCT
GGATTACAGTTTTAGGTAAT

Product: AhpC/Tsa family transporter peroxynitrite reductase

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSVLVGRKAPDFTVAAVMGNGEIVDKFNLHEHLKGKYGLVFFYPLDFTFVCPSELIALDHRIEEFKRRNVEVVAVSIDSH
FTHNAYRNTPVKNGGIGPVRFTLAADMTHSICQSYGVEHPVAGVAFRGAFVIDTNGMVRSQIVNDLPIGRNIDEILRIID
AVQFFEENGEVCPAGWQKGQAGMKASPKGVAEYLSEHSESL

Sequences:

>Translated_201_residues
MSVLVGRKAPDFTVAAVMGNGEIVDKFNLHEHLKGKYGLVFFYPLDFTFVCPSELIALDHRIEEFKRRNVEVVAVSIDSH
FTHNAYRNTPVKNGGIGPVRFTLAADMTHSICQSYGVEHPVAGVAFRGAFVIDTNGMVRSQIVNDLPIGRNIDEILRIID
AVQFFEENGEVCPAGWQKGQAGMKASPKGVAEYLSEHSESL
>Mature_200_residues
SVLVGRKAPDFTVAAVMGNGEIVDKFNLHEHLKGKYGLVFFYPLDFTFVCPSELIALDHRIEEFKRRNVEVVAVSIDSHF
THNAYRNTPVKNGGIGPVRFTLAADMTHSICQSYGVEHPVAGVAFRGAFVIDTNGMVRSQIVNDLPIGRNIDEILRIIDA
VQFFEENGEVCPAGWQKGQAGMKASPKGVAEYLSEHSESL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=193, Percent_Identity=48.7046632124352, Blast_Score=202, Evalue=1e-52,
Organism=Homo sapiens, GI32455266, Length=193, Percent_Identity=48.7046632124352, Blast_Score=202, Evalue=1e-52,
Organism=Homo sapiens, GI32455264, Length=193, Percent_Identity=48.7046632124352, Blast_Score=202, Evalue=1e-52,
Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=47.4226804123711, Blast_Score=197, Evalue=4e-51,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=46.3541666666667, Blast_Score=188, Evalue=2e-48,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=48.4375, Blast_Score=187, Evalue=4e-48,
Organism=Homo sapiens, GI32483377, Length=189, Percent_Identity=48.6772486772487, Blast_Score=187, Evalue=7e-48,
Organism=Homo sapiens, GI33188454, Length=106, Percent_Identity=44.3396226415094, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4758638, Length=208, Percent_Identity=28.3653846153846, Blast_Score=78, Evalue=5e-15,
Organism=Escherichia coli, GI1786822, Length=168, Percent_Identity=35.1190476190476, Blast_Score=115, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193204376, Length=194, Percent_Identity=48.4536082474227, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI32565831, Length=194, Percent_Identity=48.4536082474227, Blast_Score=188, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17554494, Length=189, Percent_Identity=44.4444444444444, Blast_Score=173, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI25153706, Length=185, Percent_Identity=29.7297297297297, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323613, Length=194, Percent_Identity=40.7216494845361, Blast_Score=161, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6320661, Length=194, Percent_Identity=39.1752577319588, Blast_Score=152, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6319407, Length=181, Percent_Identity=28.1767955801105, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24656348, Length=195, Percent_Identity=47.1794871794872, Blast_Score=193, Evalue=6e-50,
Organism=Drosophila melanogaster, GI17864676, Length=195, Percent_Identity=47.1794871794872, Blast_Score=193, Evalue=6e-50,
Organism=Drosophila melanogaster, GI17738015, Length=198, Percent_Identity=45.4545454545455, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI17157991, Length=192, Percent_Identity=45.8333333333333, Blast_Score=176, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24641739, Length=192, Percent_Identity=45.8333333333333, Blast_Score=176, Evalue=6e-45,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=45.0261780104712, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24581278, Length=185, Percent_Identity=27.027027027027, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17975518, Length=189, Percent_Identity=29.1005291005291, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24652436, Length=189, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24652434, Length=189, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22166; Mature: 22034

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVGRKAPDFTVAAVMGNGEIVDKFNLHEHLKGKYGLVFFYPLDFTFVCPSELIALDH
CCEECCCCCCCEEEEEEECCCCEEEECCHHHHCCCCCCEEEEEECCEEEECHHHHHHHHH
RIEEFKRRNVEVVAVSIDSHFTHNAYRNTPVKNGGIGPVRFTLAADMTHSICQSYGVEHP
HHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCC
VAGVAFRGAFVIDTNGMVRSQIVNDLPIGRNIDEILRIIDAVQFFEENGEVCPAGWQKGQ
CCCEEECCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AGMKASPKGVAEYLSEHSESL
CCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLVGRKAPDFTVAAVMGNGEIVDKFNLHEHLKGKYGLVFFYPLDFTFVCPSELIALDH
CEECCCCCCCEEEEEEECCCCEEEECCHHHHCCCCCCEEEEEECCEEEECHHHHHHHHH
RIEEFKRRNVEVVAVSIDSHFTHNAYRNTPVKNGGIGPVRFTLAADMTHSICQSYGVEHP
HHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCC
VAGVAFRGAFVIDTNGMVRSQIVNDLPIGRNIDEILRIIDAVQFFEENGEVCPAGWQKGQ
CCCEEECCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AGMKASPKGVAEYLSEHSESL
CCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]