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The map label for this gene is apaH

Identifier: 148361257

GI number: 148361257

Start: 3485234

End: 3486064

Strand: Reverse

Name: apaH

Synonym: LPC_3231

Alternate gene names: 148361257

Gene position: 3486064-3485234 (Counterclockwise)

Preceding gene: 148361258

Following gene: 148361256

Centisome position: 97.47

GC content: 45.37

Gene sequence:

>831_bases
GTGCCTGATTATGCAATAGGGGATGTACAAGGTTGTTATGATCCTTTACAACGTTTGCTTGAGCTAATCGATTTTAACGA
GAAGGAAGATTGCTTGTGGTTTGTTGGGGACTTGGTAAACCGCGGTCCTGATTCATTGGCTGTATTACGGTTTATTTATT
CCTTACCTGTGAAACCCAAAATAACCTTGGGTAATCATGATTTGCATTTATTAGGCTTATTATTCGGCGGGCAACCCTGG
AAAGGGCATGATGATACACTTGAAGAGGTGATGCTGGCTGATGATGGAGAGGAGCTTGGGCATTGGTTGCGCAAGCAATC
CCTTCTTTGCAGGTCATCTGAGTTAAACATAGTCATGTGTCATGCAGGTATTGCTCCTTTATGGGATTTATCGAAGGCCG
TGGGCTTGGCTAATGAATTGGAAGCGGTGCTTTCAGGCGATTCATATCACGAATTTTTCGCCCAGATGTACGGCAATAAG
CCGGATATTTGGTCAGATGATTTGGTTGGACTGGATAGGTTACGAGTCATTACCAATTATTTTACCCGGATGCGCTATTG
TGATGCCCATGGACGATTAGATTTGGGTTATAAGGGGACTTTATCCAAAGCCCCCAATCATCTGTATCCCTGGTTTGAAG
TGCCATGCCGAAAAGAAATTGAAATGGATATCGTTTTTGGTCATTGGGCGGCGCTCATGGGGCGAAGTTCTCATCCGCGA
ATTCATGCGATAGATACCGGATGTCTTTGGGGAGGGCAATTAACGGCATTACGCCTGCAGGACAGGCAACGCTTTTCGGT
ACCCGGGTATGGGGTTAGTCGTTTCGAATAA

Upstream 100 bases:

>100_bases
AGTGCGATTGCAATAGCGCCTTTGCAACGATTGGCAGCAAATGGCCAATGGCAGAATATTGAGCAGGATATGTCCCAATT
GACATTTGGAGCAAAACGCG

Downstream 100 bases:

>100_bases
CCTTGAGGGATAGGCATTTTTATAAACACAGGCGATAACAACGGTGAAATTTTTAAATAAAAGCACAGCATTGTTACCGG
TAATTATTTTATCGGGCCTG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MPDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPKITLGNHDLHLLGLLFGGQPW
KGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMCHAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNK
PDIWSDDLVGLDRLRVITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPR
IHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE

Sequences:

>Translated_276_residues
MPDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPKITLGNHDLHLLGLLFGGQPW
KGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMCHAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNK
PDIWSDDLVGLDRLRVITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPR
IHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE
>Mature_275_residues
PDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPKITLGNHDLHLLGLLFGGQPWK
GHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMCHAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNKP
DIWSDDLVGLDRLRVITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPRI
HAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family

Homologues:

Organism=Escherichia coli, GI1786234, Length=268, Percent_Identity=50, Blast_Score=254, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APAH_LEGPA (Q5X0V3)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_125295.1
- ProteinModelPortal:   Q5X0V3
- SMR:   Q5X0V3
- STRING:   Q5X0V3
- GeneID:   3116469
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp2993
- LegioList:   lpp2993
- eggNOG:   COG0639
- HOGENOM:   HBG724457
- OMA:   LVFGHWA
- ProtClustDB:   PRK00166
- BioCyc:   LPNE297246:LPP2993-MONOMER
- HAMAP:   MF_00199
- InterPro:   IPR004617
- InterPro:   IPR004843
- PIRSF:   PIRSF000903
- TIGRFAMs:   TIGR00668

Pfam domain/function: PF00149 Metallophos

EC number: =3.6.1.41

Molecular weight: Translated: 31363; Mature: 31232

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCE
ITLGNHDLHLLGLLFGGQPWKGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMC
EEECCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEE
HAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNKPDIWSDDLVGLDRLRVITNY
ECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
FTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPR
HHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCE
IHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE
EEEEECCEEECCCEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPK
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCE
ITLGNHDLHLLGLLFGGQPWKGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMC
EEECCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEE
HAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNKPDIWSDDLVGLDRLRVITNY
ECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
FTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPR
HHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCE
IHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE
EEEEECCEEECCCEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA