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The map label for this gene is asg [H]

Identifier: 148361185

GI number: 148361185

Start: 3419024

End: 3420034

Strand: Direct

Name: asg [H]

Synonym: LPC_3159

Alternate gene names: 148361185

Gene position: 3419024-3420034 (Clockwise)

Preceding gene: 148361178

Following gene: 148361187

Centisome position: 95.6

GC content: 41.64

Gene sequence:

>1011_bases
ATGAAAAAACGAGTTTTAATTATCAATACTGGCGGCACAATCAGTAGCATAAAAACATCGCATGGTTATGAGCCTTCGCC
AGGATTCATTCAAAAAGCGTTGGCAGACATTCCTGCTCTAAAACATCAAGAAATGCCTGACTACGTTATCAAAGAATATC
AGCCGCTACTTGATTCCTCTAATATGACCGTCACGGAATGGAACAGGATTGCCAGAGATATTGCTCACGAATATGAACAG
TTTGACGGATTTGTTGTATTACATGGCACTGATACCATGGCTTACACTGCTTCTGCTTTGTCATTTATGTTGGAGTATTT
GGGAAAACCCGTCATAGTCACTGGTTCACAGATTCCTTTATCCGAGATTCGTAATGATGCGACAGATAACCTCATTACGT
CCTTATGGCTTTGTGCTCATCAACCTATCCATGAAGTATGCATCTACTTCAATCAACATTTGTTTCGAGGCAATCGCACC
CAAAAAATCAGTGCCCAACGCTTCAATGCTTTTGATTCGCCCAACTACCCACCCTTGGCATCGATTGGTATCGATATCGA
GTTACATCAACACCGTTTATTGCCACGCCCCAAAGCACCGTTCCATCTACAAACCATTACTCCTCACTTTATCGCAAACT
TCCGCCTGTTCCCAGGCTTTGCCTCTGATGTTCTAGAGTACATTTTAAATCAACCTTTACGGGGTTTAATCCTTGAAACC
TATGGGGCAGGTAATGCCCAGAACAATGATCCAAGATTTTTAAGTTTGCTTAAGGAGGCTTGCGGCAGGGGGGTTATTAT
TATTAATTGCACCCAATGCCACCAGGGGAAAGTGGAAATGAATCAATACGCAACAGGACATACTTTAAAAGAAGCAGGCT
TGATTAGCGGTCATGATATGACACCTGAAGCAGCTCATTGCAAATTGCTGTATTTATTAAGCAAGAATCTGGAAATCCCT
GAAATCAGAAAACTGATTGAAACCAATTTGTGTGGTGAACTGCAGATTTAA

Upstream 100 bases:

>100_bases
GTTGGGGCTTTTGGCAAGTCCTGAAATTAGTTGTTATTGGTATAGCCAAGTTTTCGCTATACTTATCGAAACAATAACAC
ATCATTGATTATAAATCCGC

Downstream 100 bases:

>100_bases
GAACGAGGGATCTCCTTGCTCCAACAGAAAATATCTTTTGGAGACCTCTCGTATGCATTCGAGGCAGAGAAATCAAAATA
CACCCATTGAAAGTAACTTA

Product: L-asparaginase I

Products: NA

Alternate protein names: L-asparaginase I; L-ASNase I; L-asparagine amidohydrolase I [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKKRVLIINTGGTISSIKTSHGYEPSPGFIQKALADIPALKHQEMPDYVIKEYQPLLDSSNMTVTEWNRIARDIAHEYEQ
FDGFVVLHGTDTMAYTASALSFMLEYLGKPVIVTGSQIPLSEIRNDATDNLITSLWLCAHQPIHEVCIYFNQHLFRGNRT
QKISAQRFNAFDSPNYPPLASIGIDIELHQHRLLPRPKAPFHLQTITPHFIANFRLFPGFASDVLEYILNQPLRGLILET
YGAGNAQNNDPRFLSLLKEACGRGVIIINCTQCHQGKVEMNQYATGHTLKEAGLISGHDMTPEAAHCKLLYLLSKNLEIP
EIRKLIETNLCGELQI

Sequences:

>Translated_336_residues
MKKRVLIINTGGTISSIKTSHGYEPSPGFIQKALADIPALKHQEMPDYVIKEYQPLLDSSNMTVTEWNRIARDIAHEYEQ
FDGFVVLHGTDTMAYTASALSFMLEYLGKPVIVTGSQIPLSEIRNDATDNLITSLWLCAHQPIHEVCIYFNQHLFRGNRT
QKISAQRFNAFDSPNYPPLASIGIDIELHQHRLLPRPKAPFHLQTITPHFIANFRLFPGFASDVLEYILNQPLRGLILET
YGAGNAQNNDPRFLSLLKEACGRGVIIINCTQCHQGKVEMNQYATGHTLKEAGLISGHDMTPEAAHCKLLYLLSKNLEIP
EIRKLIETNLCGELQI
>Mature_336_residues
MKKRVLIINTGGTISSIKTSHGYEPSPGFIQKALADIPALKHQEMPDYVIKEYQPLLDSSNMTVTEWNRIARDIAHEYEQ
FDGFVVLHGTDTMAYTASALSFMLEYLGKPVIVTGSQIPLSEIRNDATDNLITSLWLCAHQPIHEVCIYFNQHLFRGNRT
QKISAQRFNAFDSPNYPPLASIGIDIELHQHRLLPRPKAPFHLQTITPHFIANFRLFPGFASDVLEYILNQPLRGLILET
YGAGNAQNNDPRFLSLLKEACGRGVIIINCTQCHQGKVEMNQYATGHTLKEAGLISGHDMTPEAAHCKLLYLLSKNLEIP
EIRKLIETNLCGELQI

Specific function: Unknown

COG id: COG0252

COG function: function code EJ; L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the asparaginase 1 family [H]

Homologues:

Organism=Homo sapiens, GI122937331, Length=358, Percent_Identity=39.9441340782123, Blast_Score=236, Evalue=2e-62,
Organism=Escherichia coli, GI1788065, Length=333, Percent_Identity=51.0510510510511, Blast_Score=337, Evalue=7e-94,
Organism=Escherichia coli, GI1789327, Length=286, Percent_Identity=22.7272727272727, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193207372, Length=361, Percent_Identity=43.4903047091413, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17558278, Length=361, Percent_Identity=43.4903047091413, Blast_Score=295, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17558280, Length=361, Percent_Identity=43.4903047091413, Blast_Score=295, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI193207374, Length=361, Percent_Identity=43.4903047091413, Blast_Score=294, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6320527, Length=338, Percent_Identity=23.6686390532544, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639609, Length=362, Percent_Identity=43.3701657458564, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24645530, Length=357, Percent_Identity=39.4957983193277, Blast_Score=258, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006033
- InterPro:   IPR006034
- InterPro:   IPR020827 [H]

Pfam domain/function: PF00710 Asparaginase [H]

EC number: =3.5.1.1 [H]

Molecular weight: Translated: 37790; Mature: 37790

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00144 ASN_GLN_ASE_1 ; PS00917 ASN_GLN_ASE_2 ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRVLIINTGGTISSIKTSHGYEPSPGFIQKALADIPALKHQEMPDYVIKEYQPLLDSS
CCCEEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHCCC
NMTVTEWNRIARDIAHEYEQFDGFVVLHGTDTMAYTASALSFMLEYLGKPVIVTGSQIPL
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEECCCCCH
SEIRNDATDNLITSLWLCAHQPIHEVCIYFNQHLFRGNRTQKISAQRFNAFDSPNYPPLA
HHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
SIGIDIELHQHRLLPRPKAPFHLQTITPHFIANFRLFPGFASDVLEYILNQPLRGLILET
CEEEEEEEHHHHCCCCCCCCEEEEECCHHHHHCCEECCCHHHHHHHHHHCCCCHHEEEEE
YGAGNAQNNDPRFLSLLKEACGRGVIIINCTQCHQGKVEMNQYATGHTLKEAGLISGHDM
CCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEHHHCCCCCHHHHCCCCCCCCC
TPEAAHCKLLYLLSKNLEIPEIRKLIETNLCGELQI
CCCHHHHEEEEEHHCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKRVLIINTGGTISSIKTSHGYEPSPGFIQKALADIPALKHQEMPDYVIKEYQPLLDSS
CCCEEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHCCC
NMTVTEWNRIARDIAHEYEQFDGFVVLHGTDTMAYTASALSFMLEYLGKPVIVTGSQIPL
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEECCCCCH
SEIRNDATDNLITSLWLCAHQPIHEVCIYFNQHLFRGNRTQKISAQRFNAFDSPNYPPLA
HHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
SIGIDIELHQHRLLPRPKAPFHLQTITPHFIANFRLFPGFASDVLEYILNQPLRGLILET
CEEEEEEEHHHHCCCCCCCCEEEEECCHHHHHCCEECCCHHHHHHHHHHCCCCHHEEEEE
YGAGNAQNNDPRFLSLLKEACGRGVIIINCTQCHQGKVEMNQYATGHTLKEAGLISGHDM
CCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEHHHCCCCCHHHHCCCCCCCCC
TPEAAHCKLLYLLSKNLEIPEIRKLIETNLCGELQI
CCCHHHHEEEEEHHCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]