Click here to switch to the map view.

The map label for this gene is ppnK [H]

Identifier: 148361136

GI number: 148361136

Start: 3364476

End: 3365363

Strand: Direct

Name: ppnK [H]

Synonym: LPC_3110

Alternate gene names: 148361136

Gene position: 3364476-3365363 (Clockwise)

Preceding gene: 148361135

Following gene: 148361137

Centisome position: 94.07

GC content: 40.65

Gene sequence:

>888_bases
ATGAAACAAAAATTTAAACGAGCCATCTTGTATGCCCGTCAACACAGAGCGAATCAGGAAGTGAATGAAAGCTTGCATCG
ACTGGTTGACTTTTTAAGCACGCAAGACATAGAAATCTTTCAGGACTCAGATACTGCGGCCAGTTTTGAATTAAAGACCC
CTGTTTTACCTAGAGAAAAGATGGGGGAAAAACACGACTTGATTATTGTCGTGGGTGGTGATGGCAGTTTACTTTCTGCC
TCACGTATGGCTATAAAAGTTAATACACCGGTCATCGGGATTAACAGGGGAAGGCTAGGTTTTTTAACGGATATTTTACC
CCAAGACATTGAGTCCCATTTAGGCCCTGTGCTTAATGGACAATATAATGAAGAAGAACGCTTCTTATTGCATACTAAAA
TATATGATAAGGAAAACAGTTATTTTGAAGGCGATGCACTCAATGATGTCGTATTAGGCAGAGGAAGTGAAACGCATTTG
ATAGAATTTGATGTTTACATCAATCAGCAGCTGGTTAGCCATTATCGTTCAGATGGAATGATTTTATCCACTCCAACTGG
CTCAACAGCCTATGCCTTGTCTGCAGGAGGACCGATAATGCATCCTCAACTCAATGCCATTGTCCTGGTACCCATGTTTT
CACACAGCCTAAGTTCCAGGCCACTCGTTATTGATGGGGAAGCAGAAATTGAATTGTATATCAGCAAATCAAATGAAACC
GATTTGCGTATCAGTTGTGATGGTCACGAATCCCGTGTCGTTAAACCGGGACAGAAAGTAGCAGTCAAAAAAAATGGTAA
TCGATTGCGTTTGTTACACCCTCTTGATTATCATTATTATGATACATTACGAAGCAAACTTGGTTGGGAATCAAAGCATC
AGGGATAA

Upstream 100 bases:

>100_bases
TGAGGTTACCCCGTTATCTATTCGTTTACGTAAAAAATTTCTCAAGGAACACGATAGAAAAAAAGCCTCTCGTACCGCCA
CAAGTGAAGAATAACACATT

Downstream 100 bases:

>100_bases
AACATGCTCACGACATTGCGCATTGAACATTTTGCTATTGTTAAACAACTGGAACTCGATTTTACACAAGGCATGACCAC
CTTTACAGGCGAAACAGGCG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKQKFKRAILYARQHRANQEVNESLHRLVDFLSTQDIEIFQDSDTAASFELKTPVLPREKMGEKHDLIIVVGGDGSLLSA
SRMAIKVNTPVIGINRGRLGFLTDILPQDIESHLGPVLNGQYNEEERFLLHTKIYDKENSYFEGDALNDVVLGRGSETHL
IEFDVYINQQLVSHYRSDGMILSTPTGSTAYALSAGGPIMHPQLNAIVLVPMFSHSLSSRPLVIDGEAEIELYISKSNET
DLRISCDGHESRVVKPGQKVAVKKNGNRLRLLHPLDYHYYDTLRSKLGWESKHQG

Sequences:

>Translated_295_residues
MKQKFKRAILYARQHRANQEVNESLHRLVDFLSTQDIEIFQDSDTAASFELKTPVLPREKMGEKHDLIIVVGGDGSLLSA
SRMAIKVNTPVIGINRGRLGFLTDILPQDIESHLGPVLNGQYNEEERFLLHTKIYDKENSYFEGDALNDVVLGRGSETHL
IEFDVYINQQLVSHYRSDGMILSTPTGSTAYALSAGGPIMHPQLNAIVLVPMFSHSLSSRPLVIDGEAEIELYISKSNET
DLRISCDGHESRVVKPGQKVAVKKNGNRLRLLHPLDYHYYDTLRSKLGWESKHQG
>Mature_295_residues
MKQKFKRAILYARQHRANQEVNESLHRLVDFLSTQDIEIFQDSDTAASFELKTPVLPREKMGEKHDLIIVVGGDGSLLSA
SRMAIKVNTPVIGINRGRLGFLTDILPQDIESHLGPVLNGQYNEEERFLLHTKIYDKENSYFEGDALNDVVLGRGSETHL
IEFDVYINQQLVSHYRSDGMILSTPTGSTAYALSAGGPIMHPQLNAIVLVPMFSHSLSSRPLVIDGEAEIELYISKSNET
DLRISCDGHESRVVKPGQKVAVKKNGNRLRLLHPLDYHYYDTLRSKLGWESKHQG

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=257, Percent_Identity=28.7937743190661, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1788968, Length=296, Percent_Identity=43.2432432432432, Blast_Score=231, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6320794, Length=244, Percent_Identity=27.8688524590164, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6325068, Length=216, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322509, Length=244, Percent_Identity=26.2295081967213, Blast_Score=109, Evalue=5e-25,
Organism=Drosophila melanogaster, GI161077047, Length=210, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573830, Length=209, Percent_Identity=33.4928229665072, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573832, Length=210, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573828, Length=209, Percent_Identity=33.4928229665072, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28573826, Length=210, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24653422, Length=277, Percent_Identity=28.158844765343, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281363321, Length=282, Percent_Identity=27.6595744680851, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281363323, Length=282, Percent_Identity=27.6595744680851, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI20129957, Length=277, Percent_Identity=28.158844765343, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24653424, Length=282, Percent_Identity=27.6595744680851, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33178; Mature: 33178

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKFKRAILYARQHRANQEVNESLHRLVDFLSTQDIEIFQDSDTAASFELKTPVLPREK
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCHHH
MGEKHDLIIVVGGDGSLLSASRMAIKVNTPVIGINRGRLGFLTDILPQDIESHLGPVLNG
CCCCCCEEEEECCCCCEEECCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
QYNEEERFLLHTKIYDKENSYFEGDALNDVVLGRGSETHLIEFDVYINQQLVSHYRSDGM
CCCCCCEEEEEEEEECCCCCEECCCCCCCEEECCCCCCEEEEEEEEECHHHHHHHCCCCE
ILSTPTGSTAYALSAGGPIMHPQLNAIVLVPMFSHSLSSRPLVIDGEAEIELYISKSNET
EEECCCCCEEEEEECCCCEECCCCCEEEEEEECCCCCCCCCEEEECCCEEEEEEECCCCC
DLRISCDGHESRVVKPGQKVAVKKNGNRLRLLHPLDYHYYDTLRSKLGWESKHQG
EEEEEECCCCCCEECCCCEEEEEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKQKFKRAILYARQHRANQEVNESLHRLVDFLSTQDIEIFQDSDTAASFELKTPVLPREK
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCHHH
MGEKHDLIIVVGGDGSLLSASRMAIKVNTPVIGINRGRLGFLTDILPQDIESHLGPVLNG
CCCCCCEEEEECCCCCEEECCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
QYNEEERFLLHTKIYDKENSYFEGDALNDVVLGRGSETHLIEFDVYINQQLVSHYRSDGM
CCCCCCEEEEEEEEECCCCCEECCCCCCCEEECCCCCCEEEEEEEEECHHHHHHHCCCCE
ILSTPTGSTAYALSAGGPIMHPQLNAIVLVPMFSHSLSSRPLVIDGEAEIELYISKSNET
EEECCCCCEEEEEECCCCEECCCCCEEEEEEECCCCCCCCCEEEECCCEEEEEEECCCCC
DLRISCDGHESRVVKPGQKVAVKKNGNRLRLLHPLDYHYYDTLRSKLGWESKHQG
EEEEEECCCCCCEECCCCEEEEEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA