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The map label for this gene is yccK [H]

Identifier: 148361133

GI number: 148361133

Start: 3360601

End: 3361611

Strand: Direct

Name: yccK [H]

Synonym: LPC_3107

Alternate gene names: 148361133

Gene position: 3360601-3361611 (Clockwise)

Preceding gene: 148361130

Following gene: 148361134

Centisome position: 93.96

GC content: 40.16

Gene sequence:

>1011_bases
ATGAAATATCGCAAATTGGGAAAGGTGGGGCCTGATGTCTCAGCATTGGGCTTCGGGTGCATGGGATTATCAGAGTTTTA
TGGCAAACCCGCTCGCCTTGATGATGCAGTCAAAATTATTCGTAATGCGCATGACCAATACCAAGTTAATTTCTTTGATA
CAGCTGATATTTATGGAAAAGGTAAAAATGAAGAATTAGTTGGTAAAGCGATAAAACCCTTTCGTAACCAGATTATACTT
GCAACGAAATGCGGAGTAGTAAGGACAGGCTCTAATGATGAAATGAGTGTCAATAATTCATCTGCTTATATCAGAACAGC
CTGTGAGAAAAGCCTAAAACGCTTAAATACTGACCACATTGATCTCTACTATTTGCATCGTTATGACCATCAAACACCAA
TTGAAGAAGTGATGGGGATAATGCATGACCTTATTGATGAAGGCAAAATTGGTTATATTGGATTATCTGAAACTGATGCT
GATACCATTCGGGCAGCTTATACAGTAGTCAAGGGCAAATTGGTTGCTGTTCAAACTGAATATTCACTTCGAGTTCGAGC
TCCGGCGACAGCGGTTTTGGGCACCTGCCGTGAACTGGGTATTTGTTTTGTTGCCTACTGCCCCATAGCACGTGGTTTCC
TCAGTGGAAAAATTAAGAAGCCCAATCTTTTAGGGACAAATGGCTTTGATTTCAGAACTAATGTTCCGCAATTCCAACCT
GAAAACTTTGCTCAAAATCTCGGCTTAGTCAATGAGCTTGAGGCCATAGGAGAAAAAACAGGTTACACCCCGGCACAATT
ATCATTAGCTTGGCTATTGGCTCAAGGAGAAGACATTATCCCCATTCCCGGAACCTCGAATCCACAACACTTAGCAGAAA
ATATGCACTCAATTGATATTTTTCTAACTCCTGAACAAATGAAAGATTTGGAAAATGCTTACAAAAATAATCCTGTTGCC
GGAAAACGATTATCCAAGGAACTGATGACAGCCTTTCATTTAAAAGAATAA

Upstream 100 bases:

>100_bases
CATTTCAGAAATAAAATCACAATCCTTAATACGTTACTGCCAAATAATTCTATACTGTATTCAACTGTCCAAATAAAACC
ATGTCAGTTGAGGATAAACC

Downstream 100 bases:

>100_bases
GCTGCATTTGAATAGCATAGGAGAATGACGCTTTCTTAACCACAAATCAGGAAACTCTCCAACACTCTAAAAACCATGTT
TACAAAAGTTAGAACAGATT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAVKIIRNAHDQYQVNFFDTADIYGKGKNEELVGKAIKPFRNQIIL
ATKCGVVRTGSNDEMSVNNSSAYIRTACEKSLKRLNTDHIDLYYLHRYDHQTPIEEVMGIMHDLIDEGKIGYIGLSETDA
DTIRAAYTVVKGKLVAVQTEYSLRVRAPATAVLGTCRELGICFVAYCPIARGFLSGKIKKPNLLGTNGFDFRTNVPQFQP
ENFAQNLGLVNELEAIGEKTGYTPAQLSLAWLLAQGEDIIPIPGTSNPQHLAENMHSIDIFLTPEQMKDLENAYKNNPVA
GKRLSKELMTAFHLKE

Sequences:

>Translated_336_residues
MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAVKIIRNAHDQYQVNFFDTADIYGKGKNEELVGKAIKPFRNQIIL
ATKCGVVRTGSNDEMSVNNSSAYIRTACEKSLKRLNTDHIDLYYLHRYDHQTPIEEVMGIMHDLIDEGKIGYIGLSETDA
DTIRAAYTVVKGKLVAVQTEYSLRVRAPATAVLGTCRELGICFVAYCPIARGFLSGKIKKPNLLGTNGFDFRTNVPQFQP
ENFAQNLGLVNELEAIGEKTGYTPAQLSLAWLLAQGEDIIPIPGTSNPQHLAENMHSIDIFLTPEQMKDLENAYKNNPVA
GKRLSKELMTAFHLKE
>Mature_336_residues
MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAVKIIRNAHDQYQVNFFDTADIYGKGKNEELVGKAIKPFRNQIIL
ATKCGVVRTGSNDEMSVNNSSAYIRTACEKSLKRLNTDHIDLYYLHRYDHQTPIEEVMGIMHDLIDEGKIGYIGLSETDA
DTIRAAYTVVKGKLVAVQTEYSLRVRAPATAVLGTCRELGICFVAYCPIARGFLSGKIKKPNLLGTNGFDFRTNVPQFQP
ENFAQNLGLVNELEAIGEKTGYTPAQLSLAWLLAQGEDIIPIPGTSNPQHLAENMHSIDIFLTPEQMKDLENAYKNNPVA
GKRLSKELMTAFHLKE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=341, Percent_Identity=29.0322580645161, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436962, Length=341, Percent_Identity=28.7390029325513, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI27436966, Length=341, Percent_Identity=28.4457478005865, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436969, Length=336, Percent_Identity=27.9761904761905, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI4504825, Length=334, Percent_Identity=27.8443113772455, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI27436971, Length=336, Percent_Identity=26.7857142857143, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI223718702, Length=314, Percent_Identity=26.4331210191083, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI41152114, Length=221, Percent_Identity=28.5067873303167, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI41327764, Length=175, Percent_Identity=32.5714285714286, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI87081735, Length=335, Percent_Identity=34.0298507462687, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788070, Length=320, Percent_Identity=32.1875, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789375, Length=314, Percent_Identity=28.0254777070064, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787674, Length=307, Percent_Identity=26.3843648208469, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788081, Length=267, Percent_Identity=27.3408239700375, Blast_Score=95, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6325169, Length=348, Percent_Identity=26.1494252873563, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=279, Percent_Identity=28.3154121863799, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=279, Percent_Identity=26.8817204301075, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=253, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6319951, Length=277, Percent_Identity=25.9927797833935, Blast_Score=93, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6325384, Length=341, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24646155, Length=184, Percent_Identity=33.1521739130435, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646159, Length=182, Percent_Identity=27.4725274725275, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37296; Mature: 37296

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAVKIIRNAHDQYQVNFFDTADIYGK
CCCCCCCCCCCCHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECHHHCCC
GKNEELVGKAIKPFRNQIILATKCGVVRTGSNDEMSVNNSSAYIRTACEKSLKRLNTDHI
CCCHHHHHHHHHHHHCCEEEEECCCEEECCCCCCEEECCCCHHHHHHHHHHHHHCCCCCE
DLYYLHRYDHQTPIEEVMGIMHDLIDEGKIGYIGLSETDADTIRAAYTVVKGKLVAVQTE
EEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCEEEEEEEC
YSLRVRAPATAVLGTCRELGICFVAYCPIARGFLSGKIKKPNLLGTNGFDFRTNVPQFQP
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCC
ENFAQNLGLVNELEAIGEKTGYTPAQLSLAWLLAQGEDIIPIPGTSNPQHLAENMHSIDI
HHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHEECCCCEEECCCCCCHHHHHCCCCEEEE
FLTPEQMKDLENAYKNNPVAGKRLSKELMTAFHLKE
EECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAVKIIRNAHDQYQVNFFDTADIYGK
CCCCCCCCCCCCHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECHHHCCC
GKNEELVGKAIKPFRNQIILATKCGVVRTGSNDEMSVNNSSAYIRTACEKSLKRLNTDHI
CCCHHHHHHHHHHHHCCEEEEECCCEEECCCCCCEEECCCCHHHHHHHHHHHHHCCCCCE
DLYYLHRYDHQTPIEEVMGIMHDLIDEGKIGYIGLSETDADTIRAAYTVVKGKLVAVQTE
EEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCEEEEEEEC
YSLRVRAPATAVLGTCRELGICFVAYCPIARGFLSGKIKKPNLLGTNGFDFRTNVPQFQP
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCC
ENFAQNLGLVNELEAIGEKTGYTPAQLSLAWLLAQGEDIIPIPGTSNPQHLAENMHSIDI
HHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHEECCCCEEECCCCCCHHHHHCCCCEEEE
FLTPEQMKDLENAYKNNPVAGKRLSKELMTAFHLKE
EECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]