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The map label for this gene is mrsA [H]

Identifier: 148361106

GI number: 148361106

Start: 3324403

End: 3325770

Strand: Reverse

Name: mrsA [H]

Synonym: LPC_3080

Alternate gene names: 148361106

Gene position: 3325770-3324403 (Counterclockwise)

Preceding gene: 148361107

Following gene: 148361104

Centisome position: 92.99

GC content: 41.08

Gene sequence:

>1368_bases
ATGAGTCAACGTAAATATTTTGGTACGGATGGAATACGGGGTCACGTTGGATTATCAAATATTAACCCTGAATTTGTTTT
AAAATTAGGCTGGGCAGTAGGCTGCGTTCTTGCAAACGGAGCGAGAAAAAAGGTAGTGATTGGTAAGGACACCAGAGTAT
CTGGCTATATGTTGGAATCGGCTTTGGAGGCAGGATTGTCCGCCGCTGGGGTTGATGTGGCATTATTAGGACCAATGCCC
ACTCCTGGAATAGCCTATCTAACACAAACATTGAGGGCTAATGCAGGCATCGTGATTAGCGCTTCTCATAATTTATTTGA
AGACAATGGCATTAAGTTTTTTTCAGCTGATGGAGGGAAACTTCCGGATAGTGTAGAACTTGCAATTGAAGCTCAATTAG
AAAAACAGTTGCAAACTGTACCTTCAGTCAAGTTGGGTAAAGCAACACGTATTAATGATGCAGCGGGTCGTTACATAGAG
TTTTGTAAATCTACGATTCCTTCCCTATCTCGACTATCCAATTTGAAAATAGTTGTGGATTGCGCCAATGGTGCAACCTA
TCATATCGCCCCAAATGTATTCTCTGAATTGGGTGCTGATGTAGTTCCTATAGGAATTAAACCAGATGGTTTTAATATCA
ATCAAGAATGTGGTTCGACAGCGCCTGAATTATTAAGAGAAAAGGTGATTGCTGTTGGGGCTGATATTGGTATTGGTTTG
GATGGAGACGGGGATCGAGTTATTTTAGTGGACTCTCTGGGAAACCTCGTAGATGGCGATCAAATTATTTATATCATTGC
CAAGGACAGACACCAACGAGGAGTACTGCATGGAGGGGTCGTAGGCACGTTGATGAGTAATTATGGTCTTGAATTAGCAA
TTACCTCATTGGGGGTTCCTTTTCAACGCTCAAAAGTAGGTGACAGGTATGTTCTTGAAACGCTAAGAGAGAAAGATTGG
AAGATTGGAGGTGAAACTTCTGGACATATTGTTTGTTTGGATAAAACAACAACAGGTGATGGAATTGTAGCGGCACTGCA
AGTTCTTTCAATTATGGTGAAGCAAAATAAAGCACTGCATGAGTTAACTGCAGGTATTCAATTGTTACCTCAAACTTTAG
TGAATTTAAAAACGAATAATGCTGCCTTGTTAGCCTCTAATCCTGATGTAATTCAGGCGGTTAAAAATTTGGAAAAACAT
CTTAATGGAGAGGGTCGAGTGTTACTCAGACCTTCTGGCACTGAGCCTTTACTGAGAGTTATGGTGGAAGGTGCTAATGC
ATCGATAGTCAAGCAACAAGCACAAATGTTATGTGATGACATCAGTCAGATCGATAAAAAATTGACTGAGAGCCTACCGT
CCACTTGA

Upstream 100 bases:

>100_bases
TAATGCAATTTATCAAGCTGCTAAAGAAATCAGTTAATAGCTCATGAGATGATCAGAAGATGACTGAGACTGGAAAAATT
AAATAATAAGGTAGGTAAGG

Downstream 100 bases:

>100_bases
GCATCTGTCTTTTTAAGTTCTAATGCAGGGGCTTTTCCAAAAGCCCCTCTGTTTCACAGTATTAAGGTATTAACTACTTG
TTGGAGCCATGGAGTGGAGC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLESALEAGLSAAGVDVALLGPMP
TPGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGKLPDSVELAIEAQLEKQLQTVPSVKLGKATRINDAAGRYIE
FCKSTIPSLSRLSNLKIVVDCANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGL
DGDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVPFQRSKVGDRYVLETLREKDW
KIGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALHELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKH
LNGEGRVLLRPSGTEPLLRVMVEGANASIVKQQAQMLCDDISQIDKKLTESLPST

Sequences:

>Translated_455_residues
MSQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLESALEAGLSAAGVDVALLGPMP
TPGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGKLPDSVELAIEAQLEKQLQTVPSVKLGKATRINDAAGRYIE
FCKSTIPSLSRLSNLKIVVDCANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGL
DGDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVPFQRSKVGDRYVLETLREKDW
KIGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALHELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKH
LNGEGRVLLRPSGTEPLLRVMVEGANASIVKQQAQMLCDDISQIDKKLTESLPST
>Mature_454_residues
SQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLESALEAGLSAAGVDVALLGPMPT
PGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGKLPDSVELAIEAQLEKQLQTVPSVKLGKATRINDAAGRYIEF
CKSTIPSLSRLSNLKIVVDCANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGLD
GDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVPFQRSKVGDRYVLETLREKDWK
IGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALHELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKHL
NGEGRVLLRPSGTEPLLRVMVEGANASIVKQQAQMLCDDISQIDKKLTESLPST

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1789566, Length=445, Percent_Identity=61.5730337078652, Blast_Score=536, Evalue=1e-153,
Organism=Escherichia coli, GI1788361, Length=462, Percent_Identity=29.4372294372294, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR005841
- InterPro:   IPR006352 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 48354; Mature: 48223

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLES
CCCCCCCCCCCCCCCCCCCCCCHHHEEEEHHHHHHHEECCCCCEEEECCCCCCHHHHHHH
ALEAGLSAAGVDVALLGPMPTPGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGK
HHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCEECCCCEEEEECCCCC
LPDSVELAIEAQLEKQLQTVPSVKLGKATRINDAAGRYIEFCKSTIPSLSRLSNLKIVVD
CCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
CANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGL
CCCCCEEEECCHHHHHCCCCEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHCCCCEEECC
DGDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVP
CCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCC
FQRSKVGDRYVLETLREKDWKIGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALH
CHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHH
ELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKHLNGEGRVLLRPSGTEPLLRV
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
MVEGANASIVKQQAQMLCDDISQIDKKLTESLPST
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLES
CCCCCCCCCCCCCCCCCCCCCHHHEEEEHHHHHHHEECCCCCEEEECCCCCCHHHHHHH
ALEAGLSAAGVDVALLGPMPTPGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGK
HHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCEECCCCEEEEECCCCC
LPDSVELAIEAQLEKQLQTVPSVKLGKATRINDAAGRYIEFCKSTIPSLSRLSNLKIVVD
CCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
CANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGL
CCCCCEEEECCHHHHHCCCCEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHCCCCEEECC
DGDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVP
CCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCC
FQRSKVGDRYVLETLREKDWKIGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALH
CHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHH
ELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKHLNGEGRVLLRPSGTEPLLRV
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
MVEGANASIVKQQAQMLCDDISQIDKKLTESLPST
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA