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The map label for this gene is nuoH [H]

Identifier: 148361095

GI number: 148361095

Start: 3311106

End: 3312128

Strand: Reverse

Name: nuoH [H]

Synonym: LPC_3068

Alternate gene names: 148361095

Gene position: 3312128-3311106 (Counterclockwise)

Preceding gene: 148361096

Following gene: 148361094

Centisome position: 92.61

GC content: 41.25

Gene sequence:

>1023_bases
ATGCTTCATACTATTGGCATACTAATTTGGATTATTATTAAAATTCTTGTGATAGTTGTCCCTTTACTGATTTCCGTGGC
CTACCTAACCTATGCGGAGCGTAAAGTGATTGGCTATATTCAAGTGCGTATCGGCCCGAACAGGGTTGGTTTAAAGGGCT
TGCTACAGCCATTTGCTGATTTATTGAAATTAATAACTAAAGAAATCATAGTTCCCACTCGATCAAATAAATACCTTTTT
GTTATTGCTCCACTTTTTGCTTTAGTTCCTTCCTTAGTCGGTTGGGCGGTAATCCCTTTTCAGGAAGGTGTTGTTCTGGC
AAATATTAACGCAGGGGTCTTATACTTATTTGCCATGAGTTCTTTGGGTGTATATGGTGTTCTTATTGCAGGGTGGGCAT
CGAATTCCAAATATGCCATGTTTGGGGCGCTGCGTAGTACTGCTCAAACAGTCTCTTACGAAATTGCAATGGGATTTGCT
CTTGTCGGGGTACTCCTGGCCGCTGGAAGCATGAACTTGACTGATATCGTTAATTCTCAAAAAGGCGGAATGCTGCATTG
GTGGTTTATTCCCTTACTTCCCCTATTCTTGGTTTTCTGGATCGCCGGTATTGCAGAAACAAACAGAGCTCCTTTTGACT
TGGCAGAAGGTGAATCAGAAATTGTTGCTGGTTTCCATGTAGAATATTCTGGTATAGGGTTCGCCTTATTCTTTCTCTCT
GAATACGCCAGTATGATTTTGATTTCAACATTTATGGCTATTTTATTCATGGGCGGATGGCTGTCACCTTTTGAAGGCAT
TACGTTCCTGGATCAAATCTTTTTTGTGGTACCCGGATTTGTTTGGTTACTTCTGAAAATTAGTTTCTTCCTTTTTGTGT
ATTTGTGGGTAAGGGCTACTTTCCCCCGATATCGTTATGACCAGCTTATGCGTTTAGGCTGGAAGGTACTTATCCCTGTG
ACTATAGTTTGGTTAATAGTAACCTCCCTCATGGTGGTTGCTCATGTCAAGCCATGGTTTTGA

Upstream 100 bases:

>100_bases
TGCGGTTGATGTTGTGTGGGTGGCAAATGCAATGCCAGAAACAGTTGACCTTGGTCACTCGTTTGCTGCAATAACAATAA
AGCGCTAGAAAGGTATAAAA

Downstream 100 bases:

>100_bases
CGGTTAGAAGAGAAGCCGATGAAAAAAGTATATCATTATATAATTCACTATGTTCGTACCTACTTACTGTTAGAGCTATT
AGCCGGTTTATGGCTAACAG

Product: hypothetical protein

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLHTIGILIWIIIKILVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFADLLKLITKEIIVPTRSNKYLF
VIAPLFALVPSLVGWAVIPFQEGVVLANINAGVLYLFAMSSLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFA
LVGVLLAAGSMNLTDIVNSQKGGMLHWWFIPLLPLFLVFWIAGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
EYASMILISTFMAILFMGGWLSPFEGITFLDQIFFVVPGFVWLLLKISFFLFVYLWVRATFPRYRYDQLMRLGWKVLIPV
TIVWLIVTSLMVVAHVKPWF

Sequences:

>Translated_340_residues
MLHTIGILIWIIIKILVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFADLLKLITKEIIVPTRSNKYLF
VIAPLFALVPSLVGWAVIPFQEGVVLANINAGVLYLFAMSSLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFA
LVGVLLAAGSMNLTDIVNSQKGGMLHWWFIPLLPLFLVFWIAGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
EYASMILISTFMAILFMGGWLSPFEGITFLDQIFFVVPGFVWLLLKISFFLFVYLWVRATFPRYRYDQLMRLGWKVLIPV
TIVWLIVTSLMVVAHVKPWF
>Mature_340_residues
MLHTIGILIWIIIKILVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFADLLKLITKEIIVPTRSNKYLF
VIAPLFALVPSLVGWAVIPFQEGVVLANINAGVLYLFAMSSLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFA
LVGVLLAAGSMNLTDIVNSQKGGMLHWWFIPLLPLFLVFWIAGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
EYASMILISTFMAILFMGGWLSPFEGITFLDQIFFVVPGFVWLLLKISFFLFVYLWVRATFPRYRYDQLMRLGWKVLIPV
TIVWLIVTSLMVVAHVKPWF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=320, Percent_Identity=42.5, Blast_Score=243, Evalue=2e-64,
Organism=Escherichia coli, GI1788618, Length=330, Percent_Identity=43.6363636363636, Blast_Score=280, Evalue=8e-77,
Organism=Escherichia coli, GI1789077, Length=228, Percent_Identity=28.0701754385965, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38034; Mature: 38034

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHTIGILIWIIIKILVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHH
LLKLITKEIIVPTRSNKYLFVIAPLFALVPSLVGWAVIPFQEGVVLANINAGVLYLFAMS
HHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHCEEEEECCCCEEEEECCCHHHHHHHHH
SLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFALVGVLLAAGSMNLTDIVNSQ
HCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
KGGMLHWWFIPLLPLFLVFWIAGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHH
EYASMILISTFMAILFMGGWLSPFEGITFLDQIFFVVPGFVWLLLKISFFLFVYLWVRAT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPRYRYDQLMRLGWKVLIPVTIVWLIVTSLMVVAHVKPWF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLHTIGILIWIIIKILVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHH
LLKLITKEIIVPTRSNKYLFVIAPLFALVPSLVGWAVIPFQEGVVLANINAGVLYLFAMS
HHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHCEEEEECCCCEEEEECCCHHHHHHHHH
SLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFALVGVLLAAGSMNLTDIVNSQ
HCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
KGGMLHWWFIPLLPLFLVFWIAGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHH
EYASMILISTFMAILFMGGWLSPFEGITFLDQIFFVVPGFVWLLLKISFFLFVYLWVRAT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPRYRYDQLMRLGWKVLIPVTIVWLIVTSLMVVAHVKPWF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA