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The map label for this gene is nuoI

Identifier: 148361094

GI number: 148361094

Start: 3310587

End: 3311087

Strand: Reverse

Name: nuoI

Synonym: LPC_3067

Alternate gene names: 148361094

Gene position: 3311087-3310587 (Counterclockwise)

Preceding gene: 148361095

Following gene: 148361093

Centisome position: 92.58

GC content: 38.32

Gene sequence:

>501_bases
ATGAAAAAAGTATATCATTATATAATTCACTATGTTCGTACCTACTTACTGTTAGAGCTATTAGCCGGTTTATGGCTAAC
AGTAAAGTATTTTTTCAGGAAAAAAATAACAGTTCAGTTTCCTGAAGAACAAACGCCACTTTCTCCAAGATTCAGGGGAC
TTTTGGCATTACGCCGTTATCCCAATGGTGAGGAGCGCTGCATTGCATGTAAATTATGTGAAGCAGTTTGTCCTGCATTG
GCTATTACAATTGAATCAGAGCAAAGAGAAGATGGATCACGCCGTACTACTCGGTATGATATTGATATGTTTAAATGCAT
TAATTGTGGATTATGTGAAGAATCTTGCCCTGTTGATTCGATCGTTGTCACTCCAATTCATCACTACCATATCAGCGAAC
GTGGTCAAAATATTATGACAAAAGAGAAGCTTTTAGCAGTAGGCGATTTGATGGAAACACAACTCGCAGCAGACAGAGCT
GCTGATGAAAAATACCGTTGA

Upstream 100 bases:

>100_bases
GAAGGTACTTATCCCTGTGACTATAGTTTGGTTAATAGTAACCTCCCTCATGGTGGTTGCTCATGTCAAGCCATGGTTTT
GACGGTTAGAAGAGAAGCCG

Downstream 100 bases:

>100_bases
TGGGGTGATTTATGCATGAATGGGTAATCCAAGCAATTTTTTACATCTTTGCATTATTGACCGTATTGTCGGCACTAATG
GTAATAAGCCAAAACAATCC

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I; NDH-1 subunit I

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MKKVYHYIIHYVRTYLLLELLAGLWLTVKYFFRKKITVQFPEEQTPLSPRFRGLLALRRYPNGEERCIACKLCEAVCPAL
AITIESEQREDGSRRTTRYDIDMFKCINCGLCEESCPVDSIVVTPIHHYHISERGQNIMTKEKLLAVGDLMETQLAADRA
ADEKYR

Sequences:

>Translated_166_residues
MKKVYHYIIHYVRTYLLLELLAGLWLTVKYFFRKKITVQFPEEQTPLSPRFRGLLALRRYPNGEERCIACKLCEAVCPAL
AITIESEQREDGSRRTTRYDIDMFKCINCGLCEESCPVDSIVVTPIHHYHISERGQNIMTKEKLLAVGDLMETQLAADRA
ADEKYR
>Mature_166_residues
MKKVYHYIIHYVRTYLLLELLAGLWLTVKYFFRKKITVQFPEEQTPLSPRFRGLLALRRYPNGEERCIACKLCEAVCPAL
AITIESEQREDGSRRTTRYDIDMFKCINCGLCEESCPVDSIVVTPIHHYHISERGQNIMTKEKLLAVGDLMETQLAADRA
ADEKYR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

Organism=Homo sapiens, GI4505371, Length=155, Percent_Identity=59.3548387096774, Blast_Score=189, Evalue=1e-48,
Organism=Escherichia coli, GI1788617, Length=139, Percent_Identity=38.8489208633094, Blast_Score=102, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17555194, Length=161, Percent_Identity=54.6583850931677, Blast_Score=175, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17864306, Length=153, Percent_Identity=56.8627450980392, Blast_Score=183, Evalue=4e-47,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NUOI_LEGPA (Q5X1B5)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_125133.1
- HSSP:   P00198
- ProteinModelPortal:   Q5X1B5
- SMR:   Q5X1B5
- STRING:   Q5X1B5
- GeneID:   3118549
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp2828
- LegioList:   lpp2828
- eggNOG:   COG1143
- HOGENOM:   HBG724359
- OMA:   LQADHLY
- ProtClustDB:   PRK05888
- BioCyc:   LPNE297246:LPP2828-MONOMER
- HAMAP:   MF_01351
- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226
- Gene3D:   G3DSA:1.10.1060.10
- TIGRFAMs:   TIGR01971

Pfam domain/function: PF00037 Fer4

EC number: =1.6.99.5

Molecular weight: Translated: 19320; Mature: 19320

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVYHYIIHYVRTYLLLELLAGLWLTVKYFFRKKITVQFPEEQTPLSPRFRGLLALRRY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHCC
PNGEERCIACKLCEAVCPALAITIESEQREDGSRRTTRYDIDMFKCINCGLCEESCPVDS
CCCCHHHHHHHHHHHHHHHHEEEECCHHCCCCCCCCEEECHHHHHHHCCCCCCCCCCCCC
IVVTPIHHYHISERGQNIMTKEKLLAVGDLMETQLAADRAADEKYR
EEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKVYHYIIHYVRTYLLLELLAGLWLTVKYFFRKKITVQFPEEQTPLSPRFRGLLALRRY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHCC
PNGEERCIACKLCEAVCPALAITIESEQREDGSRRTTRYDIDMFKCINCGLCEESCPVDS
CCCCHHHHHHHHHHHHHHHHEEEECCHHCCCCCCCCEEECHHHHHHHCCCCCCCCCCCCC
IVVTPIHHYHISERGQNIMTKEKLLAVGDLMETQLAADRAADEKYR
EEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA