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The map label for this gene is nuoL [H]

Identifier: 148361091

GI number: 148361091

Start: 3307615

End: 3309588

Strand: Reverse

Name: nuoL [H]

Synonym: LPC_3064

Alternate gene names: 148361091

Gene position: 3309588-3307615 (Counterclockwise)

Preceding gene: 148361092

Following gene: 148361090

Centisome position: 92.54

GC content: 39.97

Gene sequence:

>1974_bases
GTGAGTATTCAACAAGTCTGCTTAGTAATCGTTTTGACTCCCCTTGTTGGTTCTGCTATAGCAGGATTTTTTAGAAACCA
GATTGGACGAGTCGGAGCTCATACTGTAACTATTTTAGGCGTAACTATTTCCTTATTATGTTCAATTTTTCTTGCGTGGG
GCCTGTTTTCTGGTTCGATCCCAAACACAAATAGCCTTGTTTATCACTGGGCTAGCGGGGGTTCTTTAATTCCCTACGAA
TTTAATATTGGCTTTTTAATAGACCCGCTAAGCGTTGTCATGCTGGTTATAGTTAATTTTGTTTCTTTATTAGTCCATGT
CTACAGTATTGGGTACATGGCAGATGATGATGGTTATCAACGATTTTTTAGTTATATCTCTTTATTTACATTCATGATGC
TCATGTTAGTTAGCGCAAACAACTTTCTGCAATTATTTTTTGGCTGGGAAGGGGTTGGGCTTGTTTCTTATTTATTAATC
GGATTTTGGTATCAAAAGGAATCTGCAATAGAAGGCAGCCTTAAAGCATTTCTTGTAAACCGTGTAGGAGATTTTGGATT
TGTATTAGGAATAGGTTTAATTTTTGCTTATGCTGGAAGCCTTGATTATGAAAAAGTATTTACCAGCGCAAATTATTTAG
CAAGCCAGAACATAGAGTTATTTAGCGGCTACTCCTGGTCCCTGATTACAGTTATTTGCCTGCTGCTTTTTGTTGGCGCC
ATGGGCAAATCAGCACAGGTGCCACTTCACGTTTGGTTACCTGAGTCAATGGAGGGTCCAACCCCTATTTCAGCGCTAAT
CCATGCGGCGACAATGGTGACAGCGGGTGTTTTCATGATTGCTCGTATCTCACCTTTAATTGAATTGTCTACAGCTGCGC
TTAGCACAGTATTAGTAATCGGTGCTACAGGAGCATTGTTTACAGGAATACTGGCTTTGGTTATGAACGACATCAAACGC
GTGGTAGCATACTCCACTTTATCACAACTAGGCTATATGATGGTGGCAATGGGTGCCTCAGCCTATAGTGCCGGTATGTT
TCATTTATTGACGCATGCTTGCTTTAAAGCGCTATTGTTCCTTGGTGCTGGTTCAGTCATTATTGGCATGCATCATGAAC
AAGATATGCGGAAAATGGGTGGATTATGGAATAAAATGCCGATTACCTATGTAACCTATGTCATAGGCAGTTTGGCATTG
TGTGCATTTCCTCCTTTTGCTGGTTTTTATTCAAAAGATACCATTATTGAAGCAGCGCAGCTTTCCCAGATACCCGGTAG
CAGTTATGCTTATTTTTGTGTAACAGCAGGCGCTATGGTTACAGCATTATATACATTCAGATCCTTATTCATGACATTTC
ATGGCAAGCCACGTATGGATGAACATACATTAAGTCATCTTCATGAATCTCCATGGGTAGTATGGTTACCATTAGTATTG
CTCGCTATCCCATCAATAATTTTAGGCTATGTGCTTTACATGCCTATTCTATTTGATACACCAAGCCTCTTAGGCTCATC
AATTTTTGTTTTACCTGAGCATAATGTTTTAGCAGAACTTGCTCATGAAGTAAGCTCGCCATTTGCAAGTGCTGTTCATG
CGATTTATTCCTTGCCATTTTGGATTACAGTACTCGGAGCAATTATTGCCTGGGTTTGTTATATTGCGGTTCCATCTATT
CCTGGTTATTTAGCCAGGTATTTTTCAATTATTTACTCTATTTTACTTAATAAATACGGGTTTGATCGCTTTAACGAGCT
GTTCTTTGTGAAAGGAGCTAGAGGATTAGGCATTGCTTTTTACAAGATTGGTGATCAGAAACTAATCGATGGTGCAGTTG
TCAATGGTAGTGGACGCCTGGTTCGCTGGTTCTCTGGGAAAGGGCGAAAGATACAAAGTGGGTACATCTATCATTATGCG
ACAGTAATGGTGTTTGGATTACTGGCCTTTTTATGCTGGTTAATCCTGGACTGA

Upstream 100 bases:

>100_bases
GCCGCTGAAGCAGCAATAGGTTTGGCCATAGTCATGTTGCTTTATAGAAACAGAGGCAATATTGACGTTGATAAAATGAA
TCATTTAAAAGGTTAAAATC

Downstream 100 bases:

>100_bases
AGATAAGGTGAAGGTATGCATTATTTGCTCAATTTATTAATTTGGTTACCAATATTAGGTGGCGTTTTTGTTTTGCTGAC
TGGGGATGATAAAAATCCAA

Product: NADH dehydrogenase I subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 657; Mature: 656

Protein sequence:

>657_residues
MSIQQVCLVIVLTPLVGSAIAGFFRNQIGRVGAHTVTILGVTISLLCSIFLAWGLFSGSIPNTNSLVYHWASGGSLIPYE
FNIGFLIDPLSVVMLVIVNFVSLLVHVYSIGYMADDDGYQRFFSYISLFTFMMLMLVSANNFLQLFFGWEGVGLVSYLLI
GFWYQKESAIEGSLKAFLVNRVGDFGFVLGIGLIFAYAGSLDYEKVFTSANYLASQNIELFSGYSWSLITVICLLLFVGA
MGKSAQVPLHVWLPESMEGPTPISALIHAATMVTAGVFMIARISPLIELSTAALSTVLVIGATGALFTGILALVMNDIKR
VVAYSTLSQLGYMMVAMGASAYSAGMFHLLTHACFKALLFLGAGSVIIGMHHEQDMRKMGGLWNKMPITYVTYVIGSLAL
CAFPPFAGFYSKDTIIEAAQLSQIPGSSYAYFCVTAGAMVTALYTFRSLFMTFHGKPRMDEHTLSHLHESPWVVWLPLVL
LAIPSIILGYVLYMPILFDTPSLLGSSIFVLPEHNVLAELAHEVSSPFASAVHAIYSLPFWITVLGAIIAWVCYIAVPSI
PGYLARYFSIIYSILLNKYGFDRFNELFFVKGARGLGIAFYKIGDQKLIDGAVVNGSGRLVRWFSGKGRKIQSGYIYHYA
TVMVFGLLAFLCWLILD

Sequences:

>Translated_657_residues
MSIQQVCLVIVLTPLVGSAIAGFFRNQIGRVGAHTVTILGVTISLLCSIFLAWGLFSGSIPNTNSLVYHWASGGSLIPYE
FNIGFLIDPLSVVMLVIVNFVSLLVHVYSIGYMADDDGYQRFFSYISLFTFMMLMLVSANNFLQLFFGWEGVGLVSYLLI
GFWYQKESAIEGSLKAFLVNRVGDFGFVLGIGLIFAYAGSLDYEKVFTSANYLASQNIELFSGYSWSLITVICLLLFVGA
MGKSAQVPLHVWLPESMEGPTPISALIHAATMVTAGVFMIARISPLIELSTAALSTVLVIGATGALFTGILALVMNDIKR
VVAYSTLSQLGYMMVAMGASAYSAGMFHLLTHACFKALLFLGAGSVIIGMHHEQDMRKMGGLWNKMPITYVTYVIGSLAL
CAFPPFAGFYSKDTIIEAAQLSQIPGSSYAYFCVTAGAMVTALYTFRSLFMTFHGKPRMDEHTLSHLHESPWVVWLPLVL
LAIPSIILGYVLYMPILFDTPSLLGSSIFVLPEHNVLAELAHEVSSPFASAVHAIYSLPFWITVLGAIIAWVCYIAVPSI
PGYLARYFSIIYSILLNKYGFDRFNELFFVKGARGLGIAFYKIGDQKLIDGAVVNGSGRLVRWFSGKGRKIQSGYIYHYA
TVMVFGLLAFLCWLILD
>Mature_656_residues
SIQQVCLVIVLTPLVGSAIAGFFRNQIGRVGAHTVTILGVTISLLCSIFLAWGLFSGSIPNTNSLVYHWASGGSLIPYEF
NIGFLIDPLSVVMLVIVNFVSLLVHVYSIGYMADDDGYQRFFSYISLFTFMMLMLVSANNFLQLFFGWEGVGLVSYLLIG
FWYQKESAIEGSLKAFLVNRVGDFGFVLGIGLIFAYAGSLDYEKVFTSANYLASQNIELFSGYSWSLITVICLLLFVGAM
GKSAQVPLHVWLPESMEGPTPISALIHAATMVTAGVFMIARISPLIELSTAALSTVLVIGATGALFTGILALVMNDIKRV
VAYSTLSQLGYMMVAMGASAYSAGMFHLLTHACFKALLFLGAGSVIIGMHHEQDMRKMGGLWNKMPITYVTYVIGSLALC
AFPPFAGFYSKDTIIEAAQLSQIPGSSYAYFCVTAGAMVTALYTFRSLFMTFHGKPRMDEHTLSHLHESPWVVWLPLVLL
AIPSIILGYVLYMPILFDTPSLLGSSIFVLPEHNVLAELAHEVSSPFASAVHAIYSLPFWITVLGAIIAWVCYIAVPSIP
GYLARYFSIIYSILLNKYGFDRFNELFFVKGARGLGIAFYKIGDQKLIDGAVVNGSGRLVRWFSGKGRKIQSGYIYHYAT
VMVFGLLAFLCWLILD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=425, Percent_Identity=39.5294117647059, Blast_Score=298, Evalue=8e-81,
Organism=Escherichia coli, GI1788614, Length=656, Percent_Identity=37.1951219512195, Blast_Score=351, Evalue=8e-98,
Organism=Escherichia coli, GI1788829, Length=351, Percent_Identity=31.9088319088319, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1788827, Length=438, Percent_Identity=28.9954337899543, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788831, Length=347, Percent_Identity=28.2420749279539, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI2367154, Length=444, Percent_Identity=25.4504504504505, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788613, Length=393, Percent_Identity=26.2086513994911, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI145693160, Length=309, Percent_Identity=24.2718446601942, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR002128
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01010 Oxidored_q1_C; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 72031; Mature: 71900

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQQVCLVIVLTPLVGSAIAGFFRNQIGRVGAHTVTILGVTISLLCSIFLAWGLFSGSI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PNTNSLVYHWASGGSLIPYEFNIGFLIDPLSVVMLVIVNFVSLLVHVYSIGYMADDDGYQ
CCCCCEEEEEECCCCEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHH
RFFSYISLFTFMMLMLVSANNFLQLFFGWEGVGLVSYLLIGFWYQKESAIEGSLKAFLVN
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVGDFGFVLGIGLIFAYAGSLDYEKVFTSANYLASQNIELFSGYSWSLITVICLLLFVGA
HCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHCC
MGKSAQVPLHVWLPESMEGPTPISALIHAATMVTAGVFMIARISPLIELSTAALSTVLVI
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GATGALFTGILALVMNDIKRVVAYSTLSQLGYMMVAMGASAYSAGMFHLLTHACFKALLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LGAGSVIIGMHHEQDMRKMGGLWNKMPITYVTYVIGSLALCAFPPFAGFYSKDTIIEAAQ
HCCCCEEEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LSQIPGSSYAYFCVTAGAMVTALYTFRSLFMTFHGKPRMDEHTLSHLHESPWVVWLPLVL
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHH
LAIPSIILGYVLYMPILFDTPSLLGSSIFVLPEHNVLAELAHEVSSPFASAVHAIYSLPF
HHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECHHHHHHHHHHHHCHHHHHHHHHHHHHH
WITVLGAIIAWVCYIAVPSIPGYLARYFSIIYSILLNKYGFDRFNELFFVKGARGLGIAF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHCCEEEEECCCCCEEEE
YKIGDQKLIDGAVVNGSGRLVRWFSGKGRKIQSGYIYHYATVMVFGLLAFLCWLILD
EEECCCCEECCEEECCCCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIQQVCLVIVLTPLVGSAIAGFFRNQIGRVGAHTVTILGVTISLLCSIFLAWGLFSGSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PNTNSLVYHWASGGSLIPYEFNIGFLIDPLSVVMLVIVNFVSLLVHVYSIGYMADDDGYQ
CCCCCEEEEEECCCCEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHH
RFFSYISLFTFMMLMLVSANNFLQLFFGWEGVGLVSYLLIGFWYQKESAIEGSLKAFLVN
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVGDFGFVLGIGLIFAYAGSLDYEKVFTSANYLASQNIELFSGYSWSLITVICLLLFVGA
HCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHCC
MGKSAQVPLHVWLPESMEGPTPISALIHAATMVTAGVFMIARISPLIELSTAALSTVLVI
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GATGALFTGILALVMNDIKRVVAYSTLSQLGYMMVAMGASAYSAGMFHLLTHACFKALLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LGAGSVIIGMHHEQDMRKMGGLWNKMPITYVTYVIGSLALCAFPPFAGFYSKDTIIEAAQ
HCCCCEEEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LSQIPGSSYAYFCVTAGAMVTALYTFRSLFMTFHGKPRMDEHTLSHLHESPWVVWLPLVL
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHH
LAIPSIILGYVLYMPILFDTPSLLGSSIFVLPEHNVLAELAHEVSSPFASAVHAIYSLPF
HHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECHHHHHHHHHHHHCHHHHHHHHHHHHHH
WITVLGAIIAWVCYIAVPSIPGYLARYFSIIYSILLNKYGFDRFNELFFVKGARGLGIAF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHCCEEEEECCCCCEEEE
YKIGDQKLIDGAVVNGSGRLVRWFSGKGRKIQSGYIYHYATVMVFGLLAFLCWLILD
EEECCCCEECCEEECCCCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]