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The map label for this gene is nuoN [H]

Identifier: 148361089

GI number: 148361089

Start: 3304598

End: 3306037

Strand: Reverse

Name: nuoN [H]

Synonym: LPC_3061

Alternate gene names: 148361089

Gene position: 3306037-3304598 (Counterclockwise)

Preceding gene: 148361090

Following gene: 148361088

Centisome position: 92.44

GC content: 37.36

Gene sequence:

>1440_bases
ATGACATTACTAGAAAATATCCATGTAGCAATACCAGAAATGATTATTTTAATAACCGCGTGTTTGGCGTTGCTTTCTGA
TTTGTTCTTTCGTCATAAATTAAAATCAATTGCATTTTATATATCTTGTGTAGGAATTATAGTTTCTGCAGCAGTAAGCT
TTGTATTTATAGGAAGCTACAAGTTACTTATATTCAACAAATTATTTATAAGTGATGATATAAGTCATTTAATGAAACTG
TTTATTGATATCACGGTTTTATTAAGTTTTGTCTATTCCCAAAACTATCTGGATGAACGGCAAATGCCTACAGGTGATTA
TTATGTTCTGGGGCTGTTTTCAACACTAGGCATGATGATTCTTGTTTCAGCACACTCGCTGTTGTCCCTTTATCTAGGTT
TGGAGTTAATGTCATTGCCGCTCTATGCAATGACCGCTATCCGCCGAACTGATAGTGATGCATCCGAAGCGGCAATGAAA
TATTTTGTTATGGGTGCTATTGCTTCTGGTATGCTGTTGTATGGAATATCCCTGGTGTATGGGGCAACAGGAAAACTTGA
TTTATTAGATGTTGCTAATGCGGTGGCTGTCAATTGGCAGCAACAAAATACTCTTTTTGCGTTTGCAATGGTATTTATAC
TTGCCGGCGTAGGATTCAAACTGGCTGCTGTCCCTTTCCATATGTGGGCTCCAGACGTATATCAAGGGGCACCAAGCTCT
GTAACACTTTTTATTAGTACAGCACCCAAGATTGCTGCACTGGGGATGGCACTGCGATTTTTAACTATTGGATTAGTCGA
CATCACCATGCAATGGCAGCAAATTATTTTAGTCATGGCTCTCCTTTCTACCGGCATAGGTAATTTGTTAGCAGTGATTC
AAACTAGAATCAAACGCTTGTTAGCTTATTCTGCAATTTCTCATATAGGATATGCCTTATTTGGAGTTTTAGCTGCCAGC
TCTGCTGGTTATGCCGCAGCACTGTATTATATTTTAGTCTATGCTGTAATGTCAGCGGCTGGTTTTGGTTTAGTTGTATT
GATGTCAAATCATGGAATGGAAATTGATAGTATCGATGACTTAAAAGGCTTGAATAAAAGAAACCCGTGGCTGGCGTTTA
TGATGCTATTAGTCATGTTCTCAATGGCTGGCGTGCCGCCAACAGTTGGCTTCTTTACAAAATTATTGGTATTGAAGGCA
TTAGTAGATGTTCATATGACTTGGTTAGCTGTTGTAGGTTTGCTATTTACGGTTATAGGTGCCTATTATTATTTGCGAAT
TGTTAAAATTATGTTTTTTGATCAACCTGAAAATGAAAATATAGTAAGAATTGGTACAGGCAATACCATAGTTTATTCAC
TTAATTGCCTCTCCTTACTATATTTAGGTATTTTCCCAGGCGCTTTAATTGCAGCCTGTATTAATGCATTTGCAAATTAA

Upstream 100 bases:

>100_bases
CTGTAAGTCATACTTTGGCATTGGCTGATAAATCTAAACTCTAACAAAGAACTGCGATAGGCTTAAATTGCAATCAAGTT
CCTTAGCAAGGTTAAATATG

Downstream 100 bases:

>100_bases
TTAATAAACTTTAACAAAAGTACTTGCTTAGGGACCCAAGTATCAGTATACTTGCCCTCAGTTGACGCGGGGTGGAGCAG
CCTGGTAGCTCGTCGGGCTC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MTLLENIHVAIPEMIILITACLALLSDLFFRHKLKSIAFYISCVGIIVSAAVSFVFIGSYKLLIFNKLFISDDISHLMKL
FIDITVLLSFVYSQNYLDERQMPTGDYYVLGLFSTLGMMILVSAHSLLSLYLGLELMSLPLYAMTAIRRTDSDASEAAMK
YFVMGAIASGMLLYGISLVYGATGKLDLLDVANAVAVNWQQQNTLFAFAMVFILAGVGFKLAAVPFHMWAPDVYQGAPSS
VTLFISTAPKIAALGMALRFLTIGLVDITMQWQQIILVMALLSTGIGNLLAVIQTRIKRLLAYSAISHIGYALFGVLAAS
SAGYAAALYYILVYAVMSAAGFGLVVLMSNHGMEIDSIDDLKGLNKRNPWLAFMMLLVMFSMAGVPPTVGFFTKLLVLKA
LVDVHMTWLAVVGLLFTVIGAYYYLRIVKIMFFDQPENENIVRIGTGNTIVYSLNCLSLLYLGIFPGALIAACINAFAN

Sequences:

>Translated_479_residues
MTLLENIHVAIPEMIILITACLALLSDLFFRHKLKSIAFYISCVGIIVSAAVSFVFIGSYKLLIFNKLFISDDISHLMKL
FIDITVLLSFVYSQNYLDERQMPTGDYYVLGLFSTLGMMILVSAHSLLSLYLGLELMSLPLYAMTAIRRTDSDASEAAMK
YFVMGAIASGMLLYGISLVYGATGKLDLLDVANAVAVNWQQQNTLFAFAMVFILAGVGFKLAAVPFHMWAPDVYQGAPSS
VTLFISTAPKIAALGMALRFLTIGLVDITMQWQQIILVMALLSTGIGNLLAVIQTRIKRLLAYSAISHIGYALFGVLAAS
SAGYAAALYYILVYAVMSAAGFGLVVLMSNHGMEIDSIDDLKGLNKRNPWLAFMMLLVMFSMAGVPPTVGFFTKLLVLKA
LVDVHMTWLAVVGLLFTVIGAYYYLRIVKIMFFDQPENENIVRIGTGNTIVYSLNCLSLLYLGIFPGALIAACINAFAN
>Mature_478_residues
TLLENIHVAIPEMIILITACLALLSDLFFRHKLKSIAFYISCVGIIVSAAVSFVFIGSYKLLIFNKLFISDDISHLMKLF
IDITVLLSFVYSQNYLDERQMPTGDYYVLGLFSTLGMMILVSAHSLLSLYLGLELMSLPLYAMTAIRRTDSDASEAAMKY
FVMGAIASGMLLYGISLVYGATGKLDLLDVANAVAVNWQQQNTLFAFAMVFILAGVGFKLAAVPFHMWAPDVYQGAPSSV
TLFISTAPKIAALGMALRFLTIGLVDITMQWQQIILVMALLSTGIGNLLAVIQTRIKRLLAYSAISHIGYALFGVLAASS
AGYAAALYYILVYAVMSAAGFGLVVLMSNHGMEIDSIDDLKGLNKRNPWLAFMMLLVMFSMAGVPPTVGFFTKLLVLKAL
VDVHMTWLAVVGLLFTVIGAYYYLRIVKIMFFDQPENENIVRIGTGNTIVYSLNCLSLLYLGIFPGALIAACINAFAN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=307, Percent_Identity=24.7557003257329, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI145693160, Length=477, Percent_Identity=33.1236897274633, Blast_Score=228, Evalue=9e-61,
Organism=Escherichia coli, GI1788614, Length=359, Percent_Identity=28.9693593314763, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788831, Length=307, Percent_Identity=26.3843648208469, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788613, Length=386, Percent_Identity=24.8704663212435, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788827, Length=347, Percent_Identity=23.342939481268, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI2367154, Length=302, Percent_Identity=24.5033112582781, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52387; Mature: 52256

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLLENIHVAIPEMIILITACLALLSDLFFRHKLKSIAFYISCVGIIVSAAVSFVFIGSY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KLLIFNKLFISDDISHLMKLFIDITVLLSFVYSQNYLDERQMPTGDYYVLGLFSTLGMMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHH
LVSAHSLLSLYLGLELMSLPLYAMTAIRRTDSDASEAAMKYFVMGAIASGMLLYGISLVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GATGKLDLLDVANAVAVNWQQQNTLFAFAMVFILAGVGFKLAAVPFHMWAPDVYQGAPSS
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHCCHHHCCCHHHCCCCCC
VTLFISTAPKIAALGMALRFLTIGLVDITMQWQQIILVMALLSTGIGNLLAVIQTRIKRL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LAYSAISHIGYALFGVLAASSAGYAAALYYILVYAVMSAAGFGLVVLMSNHGMEIDSIDD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
LKGLNKRNPWLAFMMLLVMFSMAGVPPTVGFFTKLLVLKALVDVHMTWLAVVGLLFTVIG
HCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYYYLRIVKIMFFDQPENENIVRIGTGNTIVYSLNCLSLLYLGIFPGALIAACINAFAN
HHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA