| Definition | Legionella pneumophila str. Corby chromosome, complete genome. |
|---|---|
| Accession | NC_009494 |
| Length | 3,576,470 |
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The map label for this gene is phaB [H]
Identifier: 148360785
GI number: 148360785
Start: 691214
End: 691954
Strand: Direct
Name: phaB [H]
Synonym: LPC_2739
Alternate gene names: 148360785
Gene position: 691214-691954 (Clockwise)
Preceding gene: 148360787
Following gene: 148360784
Centisome position: 19.33
GC content: 40.62
Gene sequence:
>741_bases ATGGATAAAATGATAGCGATTGTAACTGGGGGAACAGGCGGTATTGGTTCTGCTATTAGTCAGCGCTTAGCTGATAGTTA CCAAGTTGTGGCATGCTACTATAAAGATGGAAGACATGAAGAAGCAAAAAAATGGCAAGATGAGCAAAAGCAACTTGGTT ATGACATTGATATCGTATATGGAGATATAGCTCAATATAGTGATTGCGAAAAAATCACATCCCTGGTGATGGAGCGTTAT GGCCGTATAGATGTTTTGGTTAACAACGCAGGCATTACTAAAGATTGCAGTTTAAGAAAAATGACACCTCAACAATGGCA ACAGGTTTTAGACGCCAACTTGACCAGTGTATTCAATATGACGCGCAATGTCGTTCCAGTGATGTTGGAAAGAGGTTATG GCCGTATCGTCAGTATATCTTCAATCAATGGAAGAAAAGGGCAGTTTGGCCAATGCAATTATGCTTCCACCAAGGCTGCT TTATTTGGTTTTACCAAGAGTCTTGCATTAGAAGTAGCAAGTAAAGGTATTACGGTAAACACAGTGTCGCCTGGGTATAT TGAAACTCCTATGCTGGCTGCATTGAAAGAAGATGTACTCAATTCAATTATATCCAGTATTCCTGTTGGTCGATTGGGAT ACCCAAAAGAAATTGCAGATGCCGTTGCATTTTTAGCATCACCAGATAGCGGATTTATTACGGGGGCAAATCTGGACGTC AATGGTGGTCAGTATATGTAG
Upstream 100 bases:
>100_bases AATTATTATCACCAACTTAGTATTATATATATGTCATTGACAAGAAAGTGAAATTAGATTGTAGTAATGTAATGTTACCT AGCAACAAAAGGAGTTGTCG
Downstream 100 bases:
>100_bases TCAGAGTTTGATTCGCAGATTAAGAATCTCAAGAGGTTTTGTGAACAGATTATTTACTGTTCGCAAGGCACCTTGGGATT TTGAAAAAGTGGCTGCGATC
Product: acetyoacetyl CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 246; Mature: 246
Protein sequence:
>246_residues MDKMIAIVTGGTGGIGSAISQRLADSYQVVACYYKDGRHEEAKKWQDEQKQLGYDIDIVYGDIAQYSDCEKITSLVMERY GRIDVLVNNAGITKDCSLRKMTPQQWQQVLDANLTSVFNMTRNVVPVMLERGYGRIVSISSINGRKGQFGQCNYASTKAA LFGFTKSLALEVASKGITVNTVSPGYIETPMLAALKEDVLNSIISSIPVGRLGYPKEIADAVAFLASPDSGFITGANLDV NGGQYM
Sequences:
>Translated_246_residues MDKMIAIVTGGTGGIGSAISQRLADSYQVVACYYKDGRHEEAKKWQDEQKQLGYDIDIVYGDIAQYSDCEKITSLVMERY GRIDVLVNNAGITKDCSLRKMTPQQWQQVLDANLTSVFNMTRNVVPVMLERGYGRIVSISSINGRKGQFGQCNYASTKAA LFGFTKSLALEVASKGITVNTVSPGYIETPMLAALKEDVLNSIISSIPVGRLGYPKEIADAVAFLASPDSGFITGANLDV NGGQYM >Mature_246_residues MDKMIAIVTGGTGGIGSAISQRLADSYQVVACYYKDGRHEEAKKWQDEQKQLGYDIDIVYGDIAQYSDCEKITSLVMERY GRIDVLVNNAGITKDCSLRKMTPQQWQQVLDANLTSVFNMTRNVVPVMLERGYGRIVSISSINGRKGQFGQCNYASTKAA LFGFTKSLALEVASKGITVNTVSPGYIETPMLAALKEDVLNSIISSIPVGRLGYPKEIADAVAFLASPDSGFITGANLDV NGGQYM
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=36.046511627907, Blast_Score=149, Evalue=2e-36, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=36.6255144032922, Blast_Score=125, Evalue=2e-29, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=35.9183673469388, Blast_Score=124, Evalue=6e-29, Organism=Homo sapiens, GI59889578, Length=196, Percent_Identity=36.2244897959184, Blast_Score=114, Evalue=9e-26, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=32.4324324324324, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=31.3953488372093, Blast_Score=106, Evalue=1e-23, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=32.0987654320988, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=31.4516129032258, Blast_Score=100, Evalue=8e-22, Organism=Homo sapiens, GI4504505, Length=207, Percent_Identity=29.951690821256, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI83715985, Length=259, Percent_Identity=30.5019305019305, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI66933014, Length=169, Percent_Identity=32.5443786982249, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=28.2258064516129, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=34.2541436464088, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=34.0425531914894, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=29.2682926829268, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI7657478, Length=187, Percent_Identity=31.5508021390374, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=28.6458333333333, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI109715829, Length=236, Percent_Identity=26.271186440678, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=28.7179487179487, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4503817, Length=199, Percent_Identity=26.1306532663317, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI157739938, Length=132, Percent_Identity=29.5454545454545, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=27, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=25.3886010362694, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=25.2631578947368, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI302344755, Length=109, Percent_Identity=36.697247706422, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI4503301, Length=203, Percent_Identity=26.6009852216749, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI150247226, Length=209, Percent_Identity=28.7081339712919, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI142976729, Length=196, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI226371731, Length=198, Percent_Identity=30.8080808080808, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=42.3868312757202, Blast_Score=200, Evalue=8e-53, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=34.6153846153846, Blast_Score=140, Evalue=7e-35, Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=32.6446280991736, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=34.5528455284553, Blast_Score=117, Evalue=6e-28, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=32.3651452282158, Blast_Score=114, Evalue=4e-27, Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=30.4166666666667, Blast_Score=110, Evalue=9e-26, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=27.6422764227642, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=29.9180327868852, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=30.6772908366534, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=30.5785123966942, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1786812, Length=208, Percent_Identity=28.3653846153846, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=30.1075268817204, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1787526, Length=255, Percent_Identity=27.0588235294118, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786701, Length=104, Percent_Identity=34.6153846153846, Blast_Score=64, Evalue=9e-12, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=42.6829268292683, Blast_Score=170, Evalue=8e-43, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=41.8326693227092, Blast_Score=169, Evalue=1e-42, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=33.8775510204082, Blast_Score=130, Evalue=6e-31, Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=33.8775510204082, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=32.6996197718631, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI17568967, Length=223, Percent_Identity=34.9775784753363, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=31.8548387096774, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=31.8897637795276, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=33.0827067669173, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=32.8185328185328, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=30.7984790874525, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=30.3643724696356, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=29.1666666666667, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=31.1023622047244, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17538182, Length=233, Percent_Identity=30.9012875536481, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=31.8181818181818, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17562904, Length=253, Percent_Identity=31.6205533596838, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=30.2681992337165, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=28.740157480315, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=29.0697674418605, Blast_Score=87, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=27.5132275132275, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=27.734375, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193203115, Length=239, Percent_Identity=27.6150627615063, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193203117, Length=239, Percent_Identity=27.6150627615063, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=26.8939393939394, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=28.1853281853282, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=29.9610894941634, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=29.4354838709677, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17561272, Length=190, Percent_Identity=28.9473684210526, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=28.4644194756554, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=28.6274509803922, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=30.4878048780488, Blast_Score=79, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=27.4900398406374, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=28.4263959390863, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=27.7486910994764, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=26.1538461538462, Blast_Score=72, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=115, Percent_Identity=40.8695652173913, Blast_Score=100, Evalue=1e-22, Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=27.8225806451613, Blast_Score=87, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=27.8350515463918, Blast_Score=77, Evalue=3e-15, Organism=Saccharomyces cerevisiae, GI6322227, Length=205, Percent_Identity=26.3414634146341, Blast_Score=63, Evalue=4e-11, Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=35.5371900826446, Blast_Score=147, Evalue=7e-36, Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=37.3015873015873, Blast_Score=144, Evalue=5e-35, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=34.5381526104418, Blast_Score=137, Evalue=7e-33, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=36.6141732283465, Blast_Score=132, Evalue=2e-31, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=33.7301587301587, Blast_Score=124, Evalue=8e-29, Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=29.7520661157025, Blast_Score=118, Evalue=3e-27, Organism=Drosophila melanogaster, GI17737361, Length=231, Percent_Identity=32.034632034632, Blast_Score=104, Evalue=5e-23, Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=30.327868852459, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24644337, Length=201, Percent_Identity=35.3233830845771, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI18859837, Length=231, Percent_Identity=31.1688311688312, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=27.8350515463918, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI24641232, Length=236, Percent_Identity=30.9322033898305, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=30.7291666666667, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24581726, Length=171, Percent_Identity=29.8245614035088, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI116007236, Length=223, Percent_Identity=30.0448430493274, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665247, Length=202, Percent_Identity=30.6930693069307, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=30.6930693069307, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI221331218, Length=200, Percent_Identity=30.5, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=30.5, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=30.7291666666667, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24640442, Length=215, Percent_Identity=30.6976744186047, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24665264, Length=200, Percent_Identity=29.5, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI281364892, Length=171, Percent_Identity=29.2397660818713, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26735; Mature: 26735
Theoretical pI: Translated: 6.00; Mature: 6.00
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDKMIAIVTGGTGGIGSAISQRLADSYQVVACYYKDGRHEEAKKWQDEQKQLGYDIDIVY CCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE GDIAQYSDCEKITSLVMERYGRIDVLVNNAGITKDCSLRKMTPQQWQQVLDANLTSVFNM CCHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH TRNVVPVMLERGYGRIVSISSINGRKGQFGQCNYASTKAALFGFTKSLALEVASKGITVN HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEE TVSPGYIETPMLAALKEDVLNSIISSIPVGRLGYPKEIADAVAFLASPDSGFITGANLDV ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEC NGGQYM CCCCCC >Mature Secondary Structure MDKMIAIVTGGTGGIGSAISQRLADSYQVVACYYKDGRHEEAKKWQDEQKQLGYDIDIVY CCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE GDIAQYSDCEKITSLVMERYGRIDVLVNNAGITKDCSLRKMTPQQWQQVLDANLTSVFNM CCHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH TRNVVPVMLERGYGRIVSISSINGRKGQFGQCNYASTKAALFGFTKSLALEVASKGITVN HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEE TVSPGYIETPMLAALKEDVLNSIISSIPVGRLGYPKEIADAVAFLASPDSGFITGANLDV ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEC NGGQYM CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]