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The map label for this gene is wrbA [H]

Identifier: 148360701

GI number: 148360701

Start: 800194

End: 800793

Strand: Direct

Name: wrbA [H]

Synonym: LPC_2648

Alternate gene names: 148360701

Gene position: 800194-800793 (Clockwise)

Preceding gene: 148360702

Following gene: 148360700

Centisome position: 22.37

GC content: 46.83

Gene sequence:

>600_bases
ATGTCTAATCCTTATATCTTGGTTTTATACTATTCTCGCACTCGCTCAACGGCACAATTAGCTCAATATATTGCTCGTGG
GGTGGAAAGTGTGTCTGGGCTTGAAGCCAGGTTACGCACTGTACCTCCTGTTTCTACCACTTGCGAAGCGGTGGATAAGC
CGGTTCCCGATGCTGGCGCAATTTATGTTTCCTTGGATGATTTGCGTCATTGTCATGGGTTGGCTTTAGGCAGCCCTACT
CGCTTTGGTAATATGGCTGCTCCAATGAAGTATTTTTGGGATGGAACTACTTCTTTGTGGCTGGGTGGGGATCTGGTGAA
CAAGCCTGCTTGTGTGTTTTCTTCTTCAGCGAGTATGCATGGTGGACAGGAGACTACCTTAATCTCCATGATGATTCCTT
TGTTACATCATGGGATGATTTTATTGGGTGTTCCTTATACTGAGCCCGCCCTAACCAGTACGCAGTCTGGTGGTACGCCT
TATGGTGTAACCCATGTGGCTGGTGGTGATAATGAGAATCCATTAAGTCAAGATGAGATTTCGTTGGCTAAAGCTCTGGG
GGAAAGATTGGGGCGTGTAGCAATGGGACTGAAGGTTTGA

Upstream 100 bases:

>100_bases
GCTGCTATATACTCATGCGTTCATTCGATAATAAGCCTTGCAATTCATTTCACGTTATTAAAATGACGAAAAAAGGCAAA
AAACGCTATGGAGCAGTATC

Downstream 100 bases:

>100_bases
TGAGAGGGTTTTAGGGGTTGATTACCCCTCTCCCTTACCCTCTCCAAAGGGGCGAGGGAATGATTAATTAAAACTAGAGT
TTTCTAAATTGATGGCTATG

Product: trp repressor binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSNPYILVLYYSRTRSTAQLAQYIARGVESVSGLEARLRTVPPVSTTCEAVDKPVPDAGAIYVSLDDLRHCHGLALGSPT
RFGNMAAPMKYFWDGTTSLWLGGDLVNKPACVFSSSASMHGGQETTLISMMIPLLHHGMILLGVPYTEPALTSTQSGGTP
YGVTHVAGGDNENPLSQDEISLAKALGERLGRVAMGLKV

Sequences:

>Translated_199_residues
MSNPYILVLYYSRTRSTAQLAQYIARGVESVSGLEARLRTVPPVSTTCEAVDKPVPDAGAIYVSLDDLRHCHGLALGSPT
RFGNMAAPMKYFWDGTTSLWLGGDLVNKPACVFSSSASMHGGQETTLISMMIPLLHHGMILLGVPYTEPALTSTQSGGTP
YGVTHVAGGDNENPLSQDEISLAKALGERLGRVAMGLKV
>Mature_198_residues
SNPYILVLYYSRTRSTAQLAQYIARGVESVSGLEARLRTVPPVSTTCEAVDKPVPDAGAIYVSLDDLRHCHGLALGSPTR
FGNMAAPMKYFWDGTTSLWLGGDLVNKPACVFSSSASMHGGQETTLISMMIPLLHHGMILLGVPYTEPALTSTQSGGTPY
GVTHVAGGDNENPLSQDEISLAKALGERLGRVAMGLKV

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=198, Percent_Identity=37.8787878787879, Blast_Score=115, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319849, Length=202, Percent_Identity=34.1584158415842, Blast_Score=88, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320235, Length=191, Percent_Identity=28.7958115183246, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319526, Length=203, Percent_Identity=31.5270935960591, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089 [H]

Pfam domain/function: PF00258 Flavodoxin_1 [H]

EC number: NA

Molecular weight: Translated: 21166; Mature: 21034

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPYILVLYYSRTRSTAQLAQYIARGVESVSGLEARLRTVPPVSTTCEAVDKPVPDAGA
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCE
IYVSLDDLRHCHGLALGSPTRFGNMAAPMKYFWDGTTSLWLGGDLVNKPACVFSSSASMH
EEEEHHHHHHHHCCCCCCCCCCCCCCCCHHEEECCCCEEEECCCCCCCCCEEEECCCCCC
GGQETTLISMMIPLLHHGMILLGVPYTEPALTSTQSGGTPYGVTHVAGGDNENPLSQDEI
CCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHH
SLAKALGERLGRVAMGLKV
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNPYILVLYYSRTRSTAQLAQYIARGVESVSGLEARLRTVPPVSTTCEAVDKPVPDAGA
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCE
IYVSLDDLRHCHGLALGSPTRFGNMAAPMKYFWDGTTSLWLGGDLVNKPACVFSSSASMH
EEEEHHHHHHHHCCCCCCCCCCCCCCCCHHEEECCCCEEEECCCCCCCCCEEEECCCCCC
GGQETTLISMMIPLLHHGMILLGVPYTEPALTSTQSGGTPYGVTHVAGGDNENPLSQDEI
CCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHH
SLAKALGERLGRVAMGLKV
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA