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The map label for this gene is murG [H]

Identifier: 148360545

GI number: 148360545

Start: 993524

End: 994615

Strand: Direct

Name: murG [H]

Synonym: LPC_2487

Alternate gene names: 148360545

Gene position: 993524-994615 (Clockwise)

Preceding gene: 148360546

Following gene: 148360544

Centisome position: 27.78

GC content: 39.56

Gene sequence:

>1092_bases
ATGAGCCCAAGTATTGTTTTTACCGGGGGAGGCACTGCCGGACATGTAACGCCTAATATCGCTTTGATTAAGGAATTTCG
AAAAGAAGGCTGGAATGTAGAATATATCGGCTCTGTTTCCGGAATTGAAAAGGAGATGATTGAGCCGATGGACATTCCTT
TTCATGGAGTCAGTAGCGGTAAATTGCGCAGGTATTTTAGTTTGAAGAACTTGCTTGATCCTTTCAAAATTGTTCTGGGA
ATTATTCAATCTTCTTTGCTATTTTATAAAATCAAACCCGATGTGGTTTTTTCAAAAGGTGGCTTTGTAGCCTTTCCTGT
GGTTGTAGGCGCCTGGTTAAATCGAATTCCTGTTGTCGCTCATGAGTCTGATATGAGTCCAGGACTTGCGAATCGCCTAT
CCTTTCCTTTCGTCAATAAAATATGCCTTACTTTTGATGCTGGCAAAAAATACTTTAAGCGTCAGGATAAAATAGAAGTG
ACGGGTACTCAAATTTCGTCACAGCTATTAACTGGAAATCCGATGAAAGGATTGGAAGTATGCCGATTTATTTCCTCCAA
AACTTGCCTGCTTGTAATGGGAGGAAGCTTAGGGGCTGGTTCAATTAACAGTTGTATTCGAAGCGCATTGAAACAATTGA
CATCAGAATTTCAAGTCATTCATCTTTGTGGCAAGGGAAAACTTGATTCTTCATTGGTTGGTGTGGAGGGATATTGCCAA
TTTGAATACGCCAATGAAGAGTTGGCTGATCTGTTCGCTGCTTCTTCTGTGGTGATTTCTCGAGCAGGAGCTAATTCTTT
GTATGAAATATTAGCATTAGGAAAACCACATATCTTAATTCCAATCTCTTCACAAGTAAGCAGAGGAGATCAAATTCAGA
ATGCAAGGTACTTCCAGGGATTGGGAATAAGCGTTGTGATTCAGGACGAGTTATTGAAAGCTGATGTTCTATTACAGGCA
GTACAGGACGTAATGCGAAAAAAAGATGAAATAGATAATAAAATCAAAGCATTAAAAATTGAGTCTGCCACTGATAAGAT
TGTGGCAATTATCAAGGAGCAAGCACATGTTCAAACCCCAAGGATTGTATGA

Upstream 100 bases:

>100_bases
TTGCAGACATTGCTCAAACCGGAGTGGATTTTATTTCAGTTGGATCCATCACCAAATCAATTCAAGCAATTGATTTGAGC
TTATTGATTAGGGAAACATT

Downstream 100 bases:

>100_bases
TTACATATGCCAACAGTGGCAAGAAGAGATATTGCCAAGTTTATGTGACTATATAAAAATCCCTAATAAATCTCCTCACT
TTGATGCAAAATGGGAAGAA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPMDIPFHGVSSGKLRRYFSLKNLLDPFKIVLG
IIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEV
TGTQISSQLLTGNPMKGLEVCRFISSKTCLLVMGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQA
VQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV

Sequences:

>Translated_363_residues
MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPMDIPFHGVSSGKLRRYFSLKNLLDPFKIVLG
IIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEV
TGTQISSQLLTGNPMKGLEVCRFISSKTCLLVMGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQA
VQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV
>Mature_362_residues
SPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPMDIPFHGVSSGKLRRYFSLKNLLDPFKIVLGI
IQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVT
GTQISSQLLTGNPMKGLEVCRFISSKTCLLVMGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQF
EYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQAV
QDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=356, Percent_Identity=25.561797752809, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39653; Mature: 39522

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPMDIPFHGVSSG
CCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCC
KLRRYFSLKNLLDPFKIVLGIIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVA
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCEEEECCCCEEHHHHHHHHHHCCCEEE
HESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVTGTQISSQLLTGNPMKGLEV
ECCCCCCCHHHHCCCCCHHHEEEEEHHHHHHHHCCCCEEEECHHHHHHHHCCCCCHHHHH
CRFISSKTCLLVMGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
HHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEECCCCEEE
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQG
EEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECHHCCCCCHHCCCHHHCC
LGISVVIQDELLKADVLLQAVQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTP
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCC
RIV
CCC
>Mature Secondary Structure 
SPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPMDIPFHGVSSG
CCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCC
KLRRYFSLKNLLDPFKIVLGIIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVA
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCEEEECCCCEEHHHHHHHHHHCCCEEE
HESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVTGTQISSQLLTGNPMKGLEV
ECCCCCCCHHHHCCCCCHHHEEEEEHHHHHHHHCCCCEEEECHHHHHHHHCCCCCHHHHH
CRFISSKTCLLVMGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
HHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEECCCCEEE
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQG
EEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECHHCCCCCHHCCCHHHCC
LGISVVIQDELLKADVLLQAVQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTP
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCC
RIV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA