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The map label for this gene is murA [H]

Identifier: 148360507

GI number: 148360507

Start: 1028211

End: 1029479

Strand: Direct

Name: murA [H]

Synonym: LPC_2448

Alternate gene names: 148360507

Gene position: 1028211-1029479 (Clockwise)

Preceding gene: 148360508

Following gene: 148360506

Centisome position: 28.75

GC content: 42.87

Gene sequence:

>1269_bases
ATGGATAAATTATTGATTAATGGTGGTAAAGCATTACATGGTGAAGTGGTCATTTCGGGAGCAAAAAACGCTGCTCTTCC
AATCATGGCTGCCAGTCTATTAGCCAGTGATCACGTCACAATATCTAATGTACCTCATCTTAAAGACATCACTACCATGA
TGGAACTGTTAGGGCAATTGGGAGCTCATTTAATTGTTGATGAAAAGATGAATGTTCAAGTTGACTCCAGTCAAGTCAAT
GAGTTTGTTGCTCCTTACGATCTGGTCAAAACAATGCGTGCCTCCATTTTGGTATTAGGCCCAATGCTGGCGCGCTTCGG
TAAGGCAGATGTTTCTTTGCCCGGTGGATGCGCCATTGGAACAAGACCAGTTGACCTGCATTTAAAAGCATTAAGAGCCA
TGGGGGCAGACATTACGGTTAAAAATGGCTACATCAATGCTCGTTGCAAAAAGGGACGTCTGCAAGGTAAACGCTTGATG
TTTGACACAGTTACTGTCACAGGAACCGAAAATGTGTTAATGGCTGCTGTGTTGGCAGAAGGCATTACTACGATTAAAAA
TGCTGCGCGTGAACCAGAAGTAGTGGACTTGGCTAACTTTCTGATTCAAATGGGAGCGAAAATTCGAGGCGCGGGTACTT
CAACTATTGAAGTAGAGGGTGTGGAGTCACTAAACGGGGGGACTTATTCAGTCATGTCCGATAGAATAGAAGCGGGCACT
TATTTGGCAGCTGGAGCGCTTACTCGTGGTCAAGTGACTGTTAAGAAAGTACGTCCTGATACTTTATTATCTCAATTATG
TAAATTCGAAGAGGCAGGCGCGGAATTAACCATTGGTGAGGATTGGGTTAGTTTAAATATGCATAACAAACGTCCTGAAG
CAGTGAATATTTCTACCGCTCCTTACCCTGCATTTGCAACGGATATGCAAGCTCAATTTATGGCAATGAATTCTGTAGCA
GAAGGTTCATCAACTATTGTAGAAACTATTTTTGAAAACCGATTCATGCACGTTCAAGAGTTACAGAGAATGGGAGCTAA
TATTCAACTCAATGGAAATACAGCCATCGTTCATGGTGTTGAAAAATTAACTGGCGCACCGGTAATGGCTACTGATTTAA
GGGCATCAGCCAGTTTAATTCTCGCGGGCCTGGTTGCTGAAGGGGAAACAGTAGTCGAGCGGATTTATCATGTTGATAGA
GGTTATGAGCGAATAGAAGAAAAGTTATCTCTATTGGGAGCGGACATTAAGAGAGTTTCTGACAGGTGA

Upstream 100 bases:

>100_bases
CAGCAATGGGTTTATGCTCAGCTTAAAGACTTTATTACCACCGGAAGGCTTCATGCTATCAGTATGAAGACATGGACAAA
AGAAGAATGGGGGAAGCAAC

Downstream 100 bases:

>100_bases
TTACAAGAGATGAATTAAGCCTTTTTTTACTGGATTTCTTGAATTGCTCTCAATACCAGGATTATGCGCCTAATGGAATT
CAAGTTGAAGGCAAAGACAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQLGAHLIVDEKMNVQVDSSQVN
EFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIGTRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLM
FDTVTVTGTENVLMAAVLAEGITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGT
YLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPEAVNISTAPYPAFATDMQAQFMAMNSVA
EGSSTIVETIFENRFMHVQELQRMGANIQLNGNTAIVHGVEKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDR
GYERIEEKLSLLGADIKRVSDR

Sequences:

>Translated_422_residues
MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQLGAHLIVDEKMNVQVDSSQVN
EFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIGTRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLM
FDTVTVTGTENVLMAAVLAEGITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGT
YLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPEAVNISTAPYPAFATDMQAQFMAMNSVA
EGSSTIVETIFENRFMHVQELQRMGANIQLNGNTAIVHGVEKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDR
GYERIEEKLSLLGADIKRVSDR
>Mature_422_residues
MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQLGAHLIVDEKMNVQVDSSQVN
EFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIGTRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLM
FDTVTVTGTENVLMAAVLAEGITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGT
YLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPEAVNISTAPYPAFATDMQAQFMAMNSVA
EGSSTIVETIFENRFMHVQELQRMGANIQLNGNTAIVHGVEKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDR
GYERIEEKLSLLGADIKRVSDR

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=60.8591885441527, Blast_Score=525, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45225; Mature: 45225

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQL
CCCEEECCCCEEECEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHC
GAHLIVDEKMNVQVDSSQVNEFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIG
CCEEEEECCCCEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLMFDTVTVTGTENVLMAAVLAE
CCCHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCCCEEEEEEEEEECCHHHHHHHHHHH
GITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGT
HHHHHHHHCCCCCHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCEEHHHHHHHHCCC
YLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPEAVNISTA
EEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCEEEECCC
PYPAFATDMQAQFMAMNSVAEGSSTIVETIFENRFMHVQELQRMGANIQLNGNTAIVHGV
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCEEEEECH
EKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDRGYERIEEKLSLLGADIKRVS
HHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DR
CC
>Mature Secondary Structure
MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQL
CCCEEECCCCEEECEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHC
GAHLIVDEKMNVQVDSSQVNEFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIG
CCEEEEECCCCEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLMFDTVTVTGTENVLMAAVLAE
CCCHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCCCEEEEEEEEEECCHHHHHHHHHHH
GITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGT
HHHHHHHHCCCCCHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCEEHHHHHHHHCCC
YLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPEAVNISTA
EEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCEEEECCC
PYPAFATDMQAQFMAMNSVAEGSSTIVETIFENRFMHVQELQRMGANIQLNGNTAIVHGV
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCEEEEECH
EKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDRGYERIEEKLSLLGADIKRVS
HHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA