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The map label for this gene is yciR [C]

Identifier: 148360463

GI number: 148360463

Start: 1070842

End: 1073157

Strand: Direct

Name: yciR [C]

Synonym: LPC_2402

Alternate gene names: 148360463

Gene position: 1070842-1073157 (Clockwise)

Preceding gene: 148360468

Following gene: 148360462

Centisome position: 29.94

GC content: 36.87

Gene sequence:

>2316_bases
ATGCGTAGGCAAGAAATCAATTATGAAAAAGTTGCCAAGGCCGCAGAAAAAATAAAAAAAAGAGGCATAGAGCCGTCTGT
TAATGAAATCCGTGACGAACTTGGTTTAGTTGGGAACCATCCGCAATTATCAATTTTGCTGGAAGAGTGGTATCACAATC
AACCAGAATTTAAAAGAAAAAGTCACACACCTTTGACTGAGAATATTAATTTAAATACCGATGAAATTCGCGAAAAAAAT
GTAGAGCTTGAAAAATCAATTTCACTGCTACGGGCAACACTCGAATCCACCGCAGATGGTATTATGATGGTTAATGGACA
TGGAGCCGTTGTCGATTGGAATCAAAAGTTTGTAGAAATGTGGCGAATTCCTTCTTATATGATGGAGTCGGGAAAAGAAA
GTATCAGTTTTGAATACATACTTGAACAACTTATTGATCCGCAATCTTTGATTGCTGATGTGCAATATCTTTATCAAAAT
CCAGAGTGGCAAGGTGAATTACCTGAGCTTCATTTCAAAGACGGTCGGATTTATGAGCGTTTTTCACAGCCTCAGCGTGT
GGGCTCACAAATAGTGGGGCGAGTATATAGTTTCCGTGATGTTACTCAAAAGAGGATGGCTCTCGATGAGTTGAGAATAC
GTGAACGTGCTATTGAAGCCAGTACACATGGTGTGGTGATTATTGACGTAACAAAAAATGAAAACAAAGTCATTTATGTC
AATCGAGCTTTCGAAAGAATCACGGGATATGGGGAGCAACATGCTTTAGGGAAAGGTTTGCTTACTTTGCTGGGTTCAAA
TTTGGAGGAGGTAAACCATAAACGTATTGAACTGGCAATTAGGGAAAGCAAAGAAGAAACAATTGAAATGGAAAGCATAA
AACGAAATGGAGAATTCTATTGGTGTGAAATCAGCGTTGCTCCTGTTAAAGATTCTTTTGGCTATGTAAAACATTATATT
TGCATTTTAAATGATGTGACTCAACGACGTGATATGGAAGATCAACTGTTGCTGCAAGCAACTTATGATTCCCTGACTAA
TTTACCGAACCGTGTCTTACTGATGGATAGAGTGGAGCAGGCCATTCTACAAGCAAGAAAGAACAAGGCAATTTTGGCTT
TTTTATTTTTGGATTTAGATCGGTTTAAACTGACTAATGATACTTTGGGACACGGTATGGGGGATAAATTATTACAAGCT
ATTGCCAATCGATTACTCATTGTTACAGAGGATTTTGATACTGTTGCCAGATTGGGGGGCGATGAGTTTGTGATATTACT
TACAGACATAGATAATATGCTGGAAGCCGAAACAATTGCACAAAATATTTTAAAAATTATAGAAAAACCTATTCAAATAG
ATCAACATAGTTTGAAAATTACAGGTAGTTTGGGAATCAGCTTTTATCCCCGAGATGGTGATGATTACGAATCTTTGATG
AAAAGTGCTGATTTGTCTATGTATCATGCGAAAGATACTGGAAGAAACAACTATCGTGTCTACGAACCTGAAATGAATAG
GCGAGTCATTAATCATATGCAATTAGACAATGCGTTAAGGGATGCTTTAAAAAATGATGAATTATTTCTGGTTTATCAAC
CATTGATTGACTTAAAGCAATCCAGAGTAGTCGGATTCGAGGCTTTAATGAGATGGCATAGCAAAATATTGGGACTGGTT
AGTCCGGCAGATTTTATACCCATGGCAGAAGAAAATGGCATGATTTTGGAAATGGGTGAATGGGCAATGAAGCAAGCTTG
CATACAAGTAAAAGAATGGCATAAAGCTGGCTTTAAAAACTTAAGTATTGCGGTGAATCTTTCTGGACGGCAGTTTCGAC
AAAAAAACTTGCCGGAGGTTGTATCGCGAGTATTAAAAAGCTCTGGTTTGCAATCGAGATTTTTGGAACTCGAATTAACT
GAAAGCTTGTTGATAGAAGATATTGATCACGTTGTAGATACTATGTATGCATTGAAAGACATGGGAACCAAGTTAGTTAT
TGATGATTTTGGTACAGGTTACTCAAGCTTGTCTTATTTAAAACAATTTCCCGTAGATAAACTGAAAATTGATCGTTCGT
TTATCACTGAAATGGTAAGCAATCAGAATGATGCGGCTATTGCTAAAGCGATTATTAACCTGGGCCACAGTTTAAATCTT
CAGGTTCTTGCGGAGGGCGTTGAAAATGAATTTCAAAGAGACTTTATAACATCTCATGGATGTGACTATGCTCAAGGATA
TTTTTTTAAGGCTCCTGATACTCCAGAAAATATATTAGAATTTTTAAAAAGTTTATCTGAATCGAAAATAAAATAA

Upstream 100 bases:

>100_bases
ATCAGAGTATTGATTAAAAAATATACTTTCGGTGCTTTTTTTGCTAAAGTTCATAGTATAAATGCCGATATTTTTATAGA
GTCATTCTAGAGAGGGATGC

Downstream 100 bases:

>100_bases
TAACTAATTCATTAAGTTGAGAATTCCTGATTTCAATAAAAACTCAAATCCCATCATAAATCTCTCCAGATCGGTATGTT
TTTTGCAAGCAAAGGTTAAA

Product: GGDEF/EAL domain-containing sensory box protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 771; Mature: 771

Protein sequence:

>771_residues
MRRQEINYEKVAKAAEKIKKRGIEPSVNEIRDELGLVGNHPQLSILLEEWYHNQPEFKRKSHTPLTENINLNTDEIREKN
VELEKSISLLRATLESTADGIMMVNGHGAVVDWNQKFVEMWRIPSYMMESGKESISFEYILEQLIDPQSLIADVQYLYQN
PEWQGELPELHFKDGRIYERFSQPQRVGSQIVGRVYSFRDVTQKRMALDELRIRERAIEASTHGVVIIDVTKNENKVIYV
NRAFERITGYGEQHALGKGLLTLLGSNLEEVNHKRIELAIRESKEETIEMESIKRNGEFYWCEISVAPVKDSFGYVKHYI
CILNDVTQRRDMEDQLLLQATYDSLTNLPNRVLLMDRVEQAILQARKNKAILAFLFLDLDRFKLTNDTLGHGMGDKLLQA
IANRLLIVTEDFDTVARLGGDEFVILLTDIDNMLEAETIAQNILKIIEKPIQIDQHSLKITGSLGISFYPRDGDDYESLM
KSADLSMYHAKDTGRNNYRVYEPEMNRRVINHMQLDNALRDALKNDELFLVYQPLIDLKQSRVVGFEALMRWHSKILGLV
SPADFIPMAEENGMILEMGEWAMKQACIQVKEWHKAGFKNLSIAVNLSGRQFRQKNLPEVVSRVLKSSGLQSRFLELELT
ESLLIEDIDHVVDTMYALKDMGTKLVIDDFGTGYSSLSYLKQFPVDKLKIDRSFITEMVSNQNDAAIAKAIINLGHSLNL
QVLAEGVENEFQRDFITSHGCDYAQGYFFKAPDTPENILEFLKSLSESKIK

Sequences:

>Translated_771_residues
MRRQEINYEKVAKAAEKIKKRGIEPSVNEIRDELGLVGNHPQLSILLEEWYHNQPEFKRKSHTPLTENINLNTDEIREKN
VELEKSISLLRATLESTADGIMMVNGHGAVVDWNQKFVEMWRIPSYMMESGKESISFEYILEQLIDPQSLIADVQYLYQN
PEWQGELPELHFKDGRIYERFSQPQRVGSQIVGRVYSFRDVTQKRMALDELRIRERAIEASTHGVVIIDVTKNENKVIYV
NRAFERITGYGEQHALGKGLLTLLGSNLEEVNHKRIELAIRESKEETIEMESIKRNGEFYWCEISVAPVKDSFGYVKHYI
CILNDVTQRRDMEDQLLLQATYDSLTNLPNRVLLMDRVEQAILQARKNKAILAFLFLDLDRFKLTNDTLGHGMGDKLLQA
IANRLLIVTEDFDTVARLGGDEFVILLTDIDNMLEAETIAQNILKIIEKPIQIDQHSLKITGSLGISFYPRDGDDYESLM
KSADLSMYHAKDTGRNNYRVYEPEMNRRVINHMQLDNALRDALKNDELFLVYQPLIDLKQSRVVGFEALMRWHSKILGLV
SPADFIPMAEENGMILEMGEWAMKQACIQVKEWHKAGFKNLSIAVNLSGRQFRQKNLPEVVSRVLKSSGLQSRFLELELT
ESLLIEDIDHVVDTMYALKDMGTKLVIDDFGTGYSSLSYLKQFPVDKLKIDRSFITEMVSNQNDAAIAKAIINLGHSLNL
QVLAEGVENEFQRDFITSHGCDYAQGYFFKAPDTPENILEFLKSLSESKIK
>Mature_771_residues
MRRQEINYEKVAKAAEKIKKRGIEPSVNEIRDELGLVGNHPQLSILLEEWYHNQPEFKRKSHTPLTENINLNTDEIREKN
VELEKSISLLRATLESTADGIMMVNGHGAVVDWNQKFVEMWRIPSYMMESGKESISFEYILEQLIDPQSLIADVQYLYQN
PEWQGELPELHFKDGRIYERFSQPQRVGSQIVGRVYSFRDVTQKRMALDELRIRERAIEASTHGVVIIDVTKNENKVIYV
NRAFERITGYGEQHALGKGLLTLLGSNLEEVNHKRIELAIRESKEETIEMESIKRNGEFYWCEISVAPVKDSFGYVKHYI
CILNDVTQRRDMEDQLLLQATYDSLTNLPNRVLLMDRVEQAILQARKNKAILAFLFLDLDRFKLTNDTLGHGMGDKLLQA
IANRLLIVTEDFDTVARLGGDEFVILLTDIDNMLEAETIAQNILKIIEKPIQIDQHSLKITGSLGISFYPRDGDDYESLM
KSADLSMYHAKDTGRNNYRVYEPEMNRRVINHMQLDNALRDALKNDELFLVYQPLIDLKQSRVVGFEALMRWHSKILGLV
SPADFIPMAEENGMILEMGEWAMKQACIQVKEWHKAGFKNLSIAVNLSGRQFRQKNLPEVVSRVLKSSGLQSRFLELELT
ESLLIEDIDHVVDTMYALKDMGTKLVIDDFGTGYSSLSYLKQFPVDKLKIDRSFITEMVSNQNDAAIAKAIINLGHSLNL
QVLAEGVENEFQRDFITSHGCDYAQGYFFKAPDTPENILEFLKSLSESKIK

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=556, Percent_Identity=33.6330935251799, Blast_Score=315, Evalue=5e-87,
Organism=Escherichia coli, GI87081921, Length=432, Percent_Identity=34.9537037037037, Blast_Score=262, Evalue=7e-71,
Organism=Escherichia coli, GI226510982, Length=441, Percent_Identity=28.7981859410431, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1790496, Length=255, Percent_Identity=32.9411764705882, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1788381, Length=554, Percent_Identity=25.812274368231, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1787055, Length=445, Percent_Identity=24.4943820224719, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1788849, Length=462, Percent_Identity=25.7575757575758, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI87081845, Length=253, Percent_Identity=30.4347826086957, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI87081743, Length=243, Percent_Identity=30.0411522633745, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788502, Length=242, Percent_Identity=28.5123966942149, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1786507, Length=265, Percent_Identity=30.5660377358491, Blast_Score=126, Evalue=7e-30,
Organism=Escherichia coli, GI87081980, Length=241, Percent_Identity=31.1203319502075, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87082096, Length=427, Percent_Identity=24.824355971897, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87081881, Length=180, Percent_Identity=33.8888888888889, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=33.9285714285714, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081977, Length=207, Percent_Identity=29.4685990338164, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI145693134, Length=198, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1787802, Length=198, Percent_Identity=29.7979797979798, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=34.3558282208589, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786584, Length=194, Percent_Identity=29.3814432989691, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788956, Length=160, Percent_Identity=36.25, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787410, Length=239, Percent_Identity=27.1966527196653, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=33.125, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=146, Percent_Identity=31.5068493150685, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789650, Length=416, Percent_Identity=20.1923076923077, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 88588; Mature: 88588

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRQEINYEKVAKAAEKIKKRGIEPSVNEIRDELGLVGNHPQLSILLEEWYHNQPEFKRK
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHC
SHTPLTENINLNTDEIREKNVELEKSISLLRATLESTADGIMMVNGHGAVVDWNQKFVEM
CCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEECHHHHHHH
WRIPSYMMESGKESISFEYILEQLIDPQSLIADVQYLYQNPEWQGELPELHFKDGRIYER
HCCHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHH
FSQPQRVGSQIVGRVYSFRDVTQKRMALDELRIRERAIEASTHGVVIIDVTKNENKVIYV
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEE
NRAFERITGYGEQHALGKGLLTLLGSNLEEVNHKRIELAIRESKEETIEMESIKRNGEFY
EHHHHHHHCCCCHHHHHHHHHHHHCCCHHHCCHHHEEEHHHHCHHHHHHHHHHHCCCCEE
WCEISVAPVKDSFGYVKHYICILNDVTQRRDMEDQLLLQATYDSLTNLPNRVLLMDRVEQ
EEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AILQARKNKAILAFLFLDLDRFKLTNDTLGHGMGDKLLQAIANRLLIVTEDFDTVARLGG
HHHHHHCCCCEEEHEEHHHHHHEECCCHHCCCCHHHHHHHHHCCEEEEECCHHHHHHCCC
DEFVILLTDIDNMLEAETIAQNILKIIEKPIQIDQHSLKITGSLGISFYPRDGDDYESLM
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCHHHHHH
KSADLSMYHAKDTGRNNYRVYEPEMNRRVINHMQLDNALRDALKNDELFLVYQPLIDLKQ
HHCCCEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
SRVVGFEALMRWHSKILGLVSPADFIPMAEENGMILEMGEWAMKQACIQVKEWHKAGFKN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCC
LSIAVNLSGRQFRQKNLPEVVSRVLKSSGLQSRFLELELTESLLIEDIDHVVDTMYALKD
EEEEEECCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGTKLVIDDFGTGYSSLSYLKQFPVDKLKIDRSFITEMVSNQNDAAIAKAIINLGHSLNL
CCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCH
QVLAEGVENEFQRDFITSHGCDYAQGYFFKAPDTPENILEFLKSLSESKIK
HHHHHHHHHHHHHHHHHHCCCCHHCCEEEECCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRQEINYEKVAKAAEKIKKRGIEPSVNEIRDELGLVGNHPQLSILLEEWYHNQPEFKRK
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHC
SHTPLTENINLNTDEIREKNVELEKSISLLRATLESTADGIMMVNGHGAVVDWNQKFVEM
CCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEECHHHHHHH
WRIPSYMMESGKESISFEYILEQLIDPQSLIADVQYLYQNPEWQGELPELHFKDGRIYER
HCCHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHH
FSQPQRVGSQIVGRVYSFRDVTQKRMALDELRIRERAIEASTHGVVIIDVTKNENKVIYV
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEE
NRAFERITGYGEQHALGKGLLTLLGSNLEEVNHKRIELAIRESKEETIEMESIKRNGEFY
EHHHHHHHCCCCHHHHHHHHHHHHCCCHHHCCHHHEEEHHHHCHHHHHHHHHHHCCCCEE
WCEISVAPVKDSFGYVKHYICILNDVTQRRDMEDQLLLQATYDSLTNLPNRVLLMDRVEQ
EEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AILQARKNKAILAFLFLDLDRFKLTNDTLGHGMGDKLLQAIANRLLIVTEDFDTVARLGG
HHHHHHCCCCEEEHEEHHHHHHEECCCHHCCCCHHHHHHHHHCCEEEEECCHHHHHHCCC
DEFVILLTDIDNMLEAETIAQNILKIIEKPIQIDQHSLKITGSLGISFYPRDGDDYESLM
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCHHHHHH
KSADLSMYHAKDTGRNNYRVYEPEMNRRVINHMQLDNALRDALKNDELFLVYQPLIDLKQ
HHCCCEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
SRVVGFEALMRWHSKILGLVSPADFIPMAEENGMILEMGEWAMKQACIQVKEWHKAGFKN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCC
LSIAVNLSGRQFRQKNLPEVVSRVLKSSGLQSRFLELELTESLLIEDIDHVVDTMYALKD
EEEEEECCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGTKLVIDDFGTGYSSLSYLKQFPVDKLKIDRSFITEMVSNQNDAAIAKAIINLGHSLNL
CCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCH
QVLAEGVENEFQRDFITSHGCDYAQGYFFKAPDTPENILEFLKSLSESKIK
HHHHHHHHHHHHHHHHHHCCCCHHCCEEEECCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]